Sex-selective hippocampal alterations after adolescent nicotine administration: Effects on neurospecific proteins

2003 ◽  
Vol 5 (6) ◽  
pp. 955-960 ◽  
Author(s):  
Zengjun Xu ◽  
Frederic Seidler ◽  
Charlotte Tate ◽  
Stephanie Garcia ◽  
William Slikker ◽  
...  
Keyword(s):  
Neurospecific Proteins ◽  
Nicotine Administration ◽  
Hippocampal Alterations

Enriched Environments for Rodents and their Interaction with Nicotine Administration

2014 ◽  
Vol 6 (3) ◽  
pp. 191-200 ◽  
Author(s):  
Patricia Mesa-Gresa ◽  
Marta Ramos-Campos ◽  
Rosa Redolat
Keyword(s):  
Nicotine Administration ◽  
Enriched Environments

scholarly journals Methionine Diet Evoked Hyperhomocysteinemia Causes Hippocampal Alterations, Metabolomics Plasma Changes and Behavioral Pattern in Wild Type Rats

2021 ◽  
Vol 22 (9) ◽  
pp. 4961
Author(s):  
Maria Kovalska ◽  
Eva Baranovicova ◽  
Dagmar Kalenska ◽  
Anna Tomascova ◽  
Marian Adamkov ◽  
...  
Keyword(s):  
Morphological Changes ◽  
Brain Area ◽  
Critical Role ◽  
Cerebrovascular Diseases ◽  
Behavioral Pattern ◽  
Cell Physiology ◽  
Male Wistar Rats ◽  
High Level ◽  
Hippocampal Alterations ◽  
The Impact

L-methionine, an essential amino acid, plays a critical role in cell physiology. High intake and/or dysregulation in methionine (Met) metabolism results in accumulation of its intermediate(s) or breakdown products in plasma, including homocysteine (Hcy). High level of Hcy in plasma, hyperhomocysteinemia (hHcy), is considered to be an independent risk factor for cerebrovascular diseases, stroke and dementias. To evoke a mild hHcy in adult male Wistar rats we used an enriched Met diet at a dose of 2 g/kg of animal weight/day in duration of 4 weeks. The study contributes to the exploration of the impact of Met enriched diet inducing mild hHcy on nervous tissue by detecting the histo-morphological, metabolomic and behavioural alterations. We found an altered plasma metabolomic profile, modified spatial and learning memory acquisition as well as remarkable histo-morphological changes such as a decrease in neurons’ vitality, alterations in the morphology of neurons in the selective vulnerable hippocampal CA 1 area of animals treated with Met enriched diet. Results of these approaches suggest that the mild hHcy alters plasma metabolome and behavioural and histo-morphological patterns in rats, likely due to the potential Met induced changes in “methylation index” of hippocampal brain area, which eventually aggravates the noxious effect of high methionine intake.

Nicotine administration to rats: Methodological considerations

Life Sciences ◽  
1987 ◽  
Vol 40 (17) ◽  
pp. 1699-1708 ◽  
Author(s):  
L.Charles Murrin ◽  
James R. Ferrer ◽  
Zeng Wanyun ◽  
Nancy J. Haley
Keyword(s):  
Nicotine Administration ◽  
Methodological Considerations

Melatonin reverses urinary system and aorta damage in the rat due to chronic nicotine administration

2004 ◽  
Vol 56 (3) ◽  
pp. 359-366 ◽  
Author(s):  
Göksel Sener ◽  
Caner Kapucu ◽  
Kübra Paskaloglu ◽  
Gül Ayanoglu-Dülger ◽  
Serap Arbak ◽  
...  
Keyword(s):  
Urinary System ◽  
Chronic Nicotine ◽  
Nicotine Administration

Effects of acute abstinence and nicotine administration on taste perception in cigarette smokers

2009 ◽  
Vol 24 (11) ◽  
pp. 1709-1715 ◽  
Author(s):  
EL Mullings ◽  
LF Donaldson ◽  
JK Melichar ◽  
MR Munafò
Keyword(s):  
Taste Perception ◽  
Cigarette Smokers ◽  
Nicotine Administration

Nicotine administration enhances NPY expression in the rat hypothalamus

2000 ◽  
Vol 867 (1-2) ◽  
pp. 157-164 ◽  
Author(s):  
Ming D Li ◽  
Justin K Kane ◽  
Steven L Parker ◽  
Kathy McAllen ◽  
Shannon G Matta ◽  
...  
Keyword(s):  
Rat Hypothalamus ◽  
Nicotine Administration

Chronic nicotine administration does not alter cognitive or mood associated behavioural parameters

2015 ◽  
Vol 22 (1) ◽  
pp. 57-63 ◽  
Author(s):  
Omamuyovwi Meashack Ijomone ◽  
Olayemi Kafilat Olaibi ◽  
Christian Mba ◽  
Ifechukwude Joachim Biose ◽  
Samuel Anthony Tete ◽  
...  
Keyword(s):  
Chronic Nicotine ◽  
Nicotine Administration

Effect of Chronic Nicotine Administration on Monoamine and Monoamine Metabolite Concentrations in Rat Brain

1987 ◽  
Vol 10 (4) ◽  
pp. 376-383 ◽  
Author(s):  
Darrell G. Kirch ◽  
Greg A. Gerhardt ◽  
Richard C. Shelton ◽  
Robert Freedman ◽  
Richard J. Wyatt
Keyword(s):  
Rat Brain ◽  
Chronic Nicotine ◽  
Nicotine Administration ◽  
Metabolite Concentrations ◽  
Monoamine Metabolite
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