A recovery-informed critical interpretive synthesis of substance craving measures used in quantitative studies in the Journal of Substance Use, 2001-2020

2021 ◽  
pp. 1-8
Author(s):  
Michael J. Silverman
2020 ◽  
Author(s):  
John Martyn Ratcliffe ◽  
Paul Galdas ◽  
Mona Kanaan

Abstract BackgroundLoneliness has received considerable attention in recent years, but has seldom been investigated through a gendered lens. This review aims to critically summarise research substantively related to men and loneliness.MethodA critical interpretive synthesis, incorporating a pre-defined search strategy, was employed to analyse a broad variety of data. The searches were conducted in July 2019, across seven databases: MEDLINE; PsycINFO; Scopus, ASSIA, SSCI; Sociological Abstracts; and Social Policy and Practice. Included studies were written in English, conducted in high income nations in Western Europe, North America, and Australasia, with no date limitations. Qualitative studies required a substantive focus on sex/men or gender/masculinities and loneliness, and quantitative studies either an explicit focus on sex differences in loneliness, or data substantially relevant to loneliness and men. Seventy-nine studies met the inclusion criteria.ResultsSeven ‘synthetic constructs’ were built: i) men’s loneliness appears more associated with their social network; ii) men may be less emotionally forthright, thus both less inclined to discuss loneliness and less likely to form meaningful relationships; iii) romantic relationships may be more important for preventing loneliness in men; iv) different measurements of loneliness do not show the same sex differences in the prevalence of loneliness; v) lonely men may be more likely to engage in risky/unhealthy behaviour; vi) feeling/being ‘insufficiently masculine’ can result in loneliness; and vii) intersections of identity facilitate different gendered results.ConclusionThese constructs offer a framework that can help inform interventions aimed at preventing/alleviating loneliness in men, and a foundation for future research. Overcoming men’s emotional reticence, and facilitating better quality social networks, appeared critical goals for interventions. Men’s emotional reticence may constitute both a barrier to discussing loneliness, and to forming loneliness preventing relationships. It also appeared to be characterised either by the construction of a masculine persona, or a fear of the repercussions for initiating intimate conversation. When attempting to ascertain whether a man is lonely, acknowledging gendered variation in survey responses is required. However, it is unclear how generalisable these ‘synthetic constructs’ are, and their potential inter-relatedness requires further research.


Author(s):  
Chester J. Calbick ◽  
Richard E. Hartman

Quantitative studies of the phenomenon associated with reactions induced by the electron beam between specimens and gases present in the electron microscope require precise knowledge and control of the local environment experienced by the portion of the specimen in the electron beam. Because of outgassing phenomena, the environment at the irradiated portion of the specimen is very different from that in any place where gas pressures and compositions can be measured. We have found that differential pumping of the specimen chamber by a 4" Orb-Ion pump, following roughing by a zeolite sorption pump, can produce a specimen-chamber pressure 100- to 1000-fold less than that in the region below the objective lens.


Author(s):  
D. R. Abrahamson ◽  
P. L. St.John ◽  
E. W. Perry

Antibodies coupled to tracers for electron microscopy have been instrumental in the ultrastructural localization of antigens within cells and tissues. Among the most popular tracers are horseradish peroxidase (HRP), an enzyme that yields an osmiophilic reaction product, and colloidal gold, an electron dense suspension of particles. Some advantages of IgG-HRP conjugates are that they are readily synthesized, relatively small, and the immunolabeling obtained in a given experiment can be evaluated in the light microscope. In contrast, colloidal gold conjugates are available in different size ranges and multiple labeling as well as quantitative studies can therefore be undertaken through particle counting. On the other hand, gold conjugates are generally larger than those of HRP but usually can not be visualized with light microscopy. Concern has been raised, however, that HRP reaction product, which is exquisitely sensitive when generated properly, may in some cases distribute to sites distant from the original binding of the conjugate and therefore result in spurious antigen localization.


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