Bioelectrical Impedance Analysis as a Means of Quantifying Upper and Lower Limb Asymmetry in Youth Elite Tennis Players: An Explorative Study

Magnetic resonance imaging (MRI) was used to evaluate and compare with anthropometry a fundamental bioelectrical impedance analysis (BIA) method for predicting muscle and adipose tissue composition in the lower limb. Healthy volunteers (eight men and eight women), aged 41 to 62 years, with mean (S.D.) body mass indices of 28.6 (5.4) kg/m2 and 25.1 (5.4) kg/m2 respectively, were subjected to MRI leg scans, from which 20-cm sections of thigh and 10-cm sections of lower leg (calf) were analysed for muscle and adipose tissue content, using specifically developed software. Muscle and adipose tissue were also predicted from anthropometric measurements of circumferences and skinfold thicknesses, and by use of fundamental BIA equations involving section impedance at 50 kHz and tissue-specific resistivities. Anthropometric assessments of circumferences, cross-sectional areas and volumes for total constituent tissues matched closely MRI estimates. Muscle volume was substantially overestimated (bias: thigh, -40%; calf, -18%) and adipose tissue underestimated (bias: thigh, 43%; calf, 8%) by anthropometry, in contrast to generally better predictions by the fundamental BIA approach for muscle (bias: thigh, -12%; calf, 5%) and adipose tissue (bias: thigh, 17%; calf, -28%). However, both methods demonstrated considerable individual variability (95% limits of agreement 20–77%). In general, there was similar reproducibility for anthropometric and fundamental BIA methods in the thigh (inter-observer residual coefficient of variation for muscle 3.5% versus 3.8%), but the latter was better in the calf (inter-observer residual coefficient of variation for muscle 8.2% versus 4.5%). This study suggests that the fundamental BIA method has advantages over anthropometry for measuring lower limb tissue composition in healthy individuals.

Download Full-text

A Prospective Study in Detection of Lower-Limb Lymphedema and Evaluation of Quality of Life After Vulvar Cancer Surgery

International Journal of Gynecological Cancer ◽

10.1097/igc.0b013e31825866d0 ◽

2012 ◽

Vol 22 (6) ◽

pp. 1081-1088 ◽

Cited By ~ 25

Author(s):

Marta Novackova ◽

Michael J. Halaska ◽

Helena Robova ◽

Ivana Mala ◽

Marek Pluta ◽

...

Keyword(s):

Quality Of Life ◽

Lower Limb ◽

Bioelectrical Impedance Analysis ◽

Vulvar Cancer ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

Cancer Surgery ◽

Control Group ◽

Inguinofemoral Lymphadenectomy

BackgroundLower-limb lymphedema is one of the most disabling adverse effects of vulvar cancer surgery. Multifrequency Bioelectrical Impedance Analysis (MFBIA) is a modern noninvasive method to detect lymphedema. The first aim of this study was to prospectively determine the prevalence of secondary lower-limb lymphedema after surgical treatment for vulvar cancer using objective methods, circumference measurements and MFBIA technique. The second aim was to compare quality of life (QoL) before and 6 months after vulvar surgery.MethodsTwenty-nine patients underwent vulvar cancer surgery in our study: 17 underwent inguinofemoral lymphadenectomy (RAD), and 12 underwent sentinel lymph node biopsy (CONS). Patients were examined before and 6 months after vulvar surgery by measuring the circumference of the lower limbs and with MFBIA. A control group of 27 healthy women was also measured. To evaluate QoL, the European Organisation for Research and Treatment of Cancer (EORTC) QoL questionnaires (QLQ-C30 and QLQ-CX24) were administered to patients before and 6 months after surgery.ResultsUsing circumference measurement, 9 lymphedemas (31%) were diagnosed: 3 (25%) in the CONS and 6 (37.5%) in the RAD group (P= 0.69). After vulvar surgery, patients in the RAD group reported more fatigue and worsening of physical and role functioning. When comparing both groups, the RAD group had significantly worse parameters in social functioning, fatigue, and dyspnea.ConclusionsLower radicality in inguinofemoral lymphadenectomy shows a trend toward lower morbidity and significantly improves QoL. Multifrequency Bioelectrical Impedance Analysis was tested in these patients as a noninvasive, objective method for lymphedema detection. Detection of lymphedema based on subjective evaluations proved to have an unsatisfactory sensitivity. Less radical surgery showed objectively better results in QoL.

Download Full-text

Bioelectrical Impedance Analysis of Water Reduction in Lower-Limb Lymphedema by Lymphaticovenular Anastomosis

Journal of Reconstructive Microsurgery ◽

10.1055/s-0038-1675368 ◽

2018 ◽

Vol 35 (04) ◽

pp. 306-314 ◽

Cited By ~ 3

Author(s):

Yoshichika Yasunaga ◽

Daisuke Yanagisawa ◽

Erika Ohata ◽

Kiyoshi Matsuo ◽

Shunsuke Yuzuriha

Keyword(s):

Lower Limb ◽

Bioelectrical Impedance Analysis ◽

Linear Regression Analysis ◽

Reduction Rate ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

Body Water ◽

Volume Reduction ◽

Water Volume ◽

The Mean

Background Although lymphedema is fundamentally abnormal accumulation of excess water in the extracellular space, previous studies have evaluated the efficacy of physiological bypass surgery (lymphaticovenular anastomosis [LVA]) for lymphedema without measuring water volume. This study clarified the water reductive effect of LVA using bioelectrical impedance analysis (BIA). Methods The efficacy of LVA for unilateral lower-limb lymphedema was evaluated using BIA in a retrospective cohort. The water volume of affected and unaffected legs was measured using multifrequency BIA before and after LVA. Preoperative measurements were undertaken after compression therapy for at least 3 months. The follow-up period after LVA was a minimum of 6 months. Results Thirty consecutive patients with unilateral lower-limb lymphedema were enrolled. The mean water volume reduction of the affected leg by LVA (ΔLBW) was 0.86 L (standard deviation [SD]: 0.86, median: 0.65) with a mean number of 3.3 anastomoses (SD: 1.7). The mean reduction rate of edema was 45.1% (SD: 36.3). Multiple linear regression analysis revealed water volume difference between the affected and unaffected legs before LVA (excess LBW) as the strongest predictor of ΔLBW (R 2 = 0.759, p < 0.01; β = 0.500, p < 0.01). Conclusion The LVA reduces the volume of accumulated body water in lower-limb lymphedema. As excess LBW most strongly predicted the amount of water volume reduction by LVA, body water volume measurement by BIA before LVA might identify patients with low excess LBW not expected to benefit from LVA, regardless of apparent differences in limb circumference.

Download Full-text

Modeling upper and lower limb muscle volume by bioelectrical impedance analysis

Journal of Applied Physiology ◽

10.1152/japplphysiol.01163.2006 ◽

2007 ◽

Vol 103 (4) ◽

pp. 1428-1435 ◽

Cited By ~ 19

Author(s):

Alexander Stahn ◽

Elmarie Terblanche ◽

Günther Strobel

Keyword(s):

Lower Limb ◽

Bioelectrical Impedance Analysis ◽

Total Error ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

Muscle Volume ◽

Lower Limb Muscle ◽

Limb Muscle ◽

Low Frequencies ◽

Appendicular Skeletal Muscle

Most studies employing bioelectrical impedance analysis (BIA) for estimating appendicular skeletal muscle mass using descriptive BIA models rely on statistical rather than biophysical principles. The aim of the present study was to evaluate the feasibility of estimating arm and leg muscle volume (MV) based on multiple bioimpedance measurements and using a recently proposed mathematical model and to compare this technique to conventional segmental BIA at high and low frequencies. MV of the arm and leg, respectively, was determined in 15 young, healthy, active men [age 22 ± 2 (SD) yr, total body fat 15.6 ± 5.1%] by magnetic resonance imaging (MRI) and BIA using a conventional and new bioimpedance model. MRI-determined MV for leg and arm was 6,268 ± 1,099 and 1,173 ± 172 cm3, respectively. Estimated MV by the new BIA model [leg: 6,294 ± 1,155 cm3 (50 kHz), 6,278 ± 1,103 cm3 (500 kHz); arm: 1,216 ± 172 cm3 (50 kHz), 1,155 ± 157 cm3 (500 kHz)] was not statistically different from MRI-determined MV (leg: P= 0.958; arm: P= 0.188). The new BIA model was superior to conventional BIA and performed best at 500 kHz for estimating leg MV as indicated by the lower relative total error [new: 3.6% (500 kHz), 5.2% (50 kHz); conventional: 7.6% (500 kHz) and 8.3% (50 kHz)]. In contrast, the new BIA model, both at 50 and 500 kHz, did not improve the accuracy for estimating arm MV [new: 10.8% (500 kHz), 10.6% (50 kHz); conventional: 11.8% (500 kHz), 11.4% (50 kHz)]. It was concluded that modeling of multiple BIA measurements has advantages for the determination of lower limb muscle volume in healthy, active adult men.

Download Full-text

Segmental bioelectrical impedance analysis of lower limb muscle mass in patients with COPD

10.1183/13993003.congress-2015.pa2214 ◽

2015 ◽

Author(s):

Deniz Dilaver ◽

Jane L. Canavan ◽

Djeya P. Kaliaraju ◽

Claire M. Nolan ◽

Sarah E. Jones ◽

...

Keyword(s):

Muscle Mass ◽

Lower Limb ◽

Bioelectrical Impedance Analysis ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

Lower Limb Muscle ◽

Limb Muscle ◽

Segmental Bioelectrical Impedance

Download Full-text

Water Reductive Effect of Lymphaticovenular Anastomosis on Upper-Limb Lymphedema: Bioelectrical Impedance Analysis and Comparison with Lower-Limb Lymphedema

Journal of Reconstructive Microsurgery ◽

10.1055/s-0040-1713670 ◽

2020 ◽

Vol 36 (09) ◽

pp. 660-666 ◽

Cited By ~ 1

Author(s):

Yoshichika Yasunaga ◽

Daisuke Yanagisawa ◽

Yuta Nakajima ◽

Shinei Mimura ◽

Miharu Kobayashi ◽

...

Keyword(s):

Upper Limb ◽

Lower Limb ◽

Bioelectrical Impedance Analysis ◽

Reduction Rate ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

Volume Reduction ◽

Water Volume ◽

Arm Lymphedema ◽

The Mean

Abstract Background We previously examined the water reductive effect of lymphaticovenular anastomosis (LVA) using bioelectrical impedance analysis (BIA) measurement on lower-limb lymphedema and revealed mean water volume reduction and edema reduction rate by leg LVA to be 0.86 L and 45.1%, respectively. This study aimed to clarify the water reductive effect of LVA on arm lymphedema and compare its results with those for leg lymphedema. Patients and Methods The efficacy of LVA for unilateral arm lymphedema was evaluated using BIA in a retrospective cohort. Limb circumference and arm body water volume (ABW) of the affected and unaffected arms were measured before and after LVA. Mean water volume reduction (ΔABW) and edema reduction rate by arm LVA were compared with values for leg LVA cited from our previous report as a historical control. Results Nineteen consecutive patients were enrolled. The mean ΔABW and edema reduction rate by BIA were 0.267 L and 46.0%, respectively. The decreasing rate of ABW by BIA was significantly larger than those of the upper extremity lymphedema index and sum of 5 circumferences measurement methods. ΔABW could be predicted by a regression line based on the preoperative water volume difference between affected and unaffected limbs. The mean edema reduction rates for arm and leg LVA were comparable. Conclusion The water reductive effect of LVA on upper-limb lymphedema was demonstrated by BIA assessment. BIA can reflect the effect of LVA more sensitively than conventional objective measurements and may facilitate the interpretation of LVA results. Although water volume reduction by arm LVA was less than that by leg LVA, the edema reduction rates were comparable.

Download Full-text