Effect of tau on the vinblastine-induced aggregation of tubulin.
1981 ◽
Vol 89
(3)
◽
pp. 680-683
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Keyword(s):
Two microtubule-associated proteins, tau and the high molecular weight microtubule-associated protein 2 (MAP 2), were purified from rat brain microtubules. Addition of either protein to pure tubulin caused microtubule assembly. In the presence of tau and 10 microM vinblastine, tubulin aggregated into spiral structures. If tau was absent, or replaced by MAP 2, little aggregation occurred in the presence of vinblastine. Thus, vinblastine may be a useful probe in elucidating the individual roles of tau and MAP 2 in microtubule assembly.
1994 ◽
Vol 131
(2)
◽
pp. 105-113
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1982 ◽
Vol 95
(3)
◽
pp. 982-986
◽
1982 ◽
Vol 92
(2)
◽
pp. 589-593
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1975 ◽
Vol 65
(1)
◽
pp. 237-241
◽
1990 ◽
Vol 48
(3)
◽
pp. 1-1
1983 ◽
Vol 96
(5)
◽
pp. 1298-1305
◽
1982 ◽
Vol 93
(1)
◽
pp. 164-174
◽
1977 ◽
Vol 72
(3)
◽
pp. 642-654
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