scholarly journals ERYTHROSIS, OR FALSE CYANOSIS

1919 ◽  
Vol 30 (3) ◽  
pp. 295-298 ◽  
Author(s):  
Christen Lundsgaard

1. In the venous blood of a patient with Vaquez' disease normal values were found for the oxygen unsaturation (reduced hemoglobin), although the total hemoglobin and oxygen capacity were abnormally high. The carbon dioxide content was normal. 2. The color of the skin and mucous membranes of this patient was more reddish than blue. 3. It is proposed to call the color of the skin in polycythemic patients erythrosis in order to distinguish the condition from cyanosis.

1919 ◽  
Vol 30 (3) ◽  
pp. 241-257 ◽  
Author(s):  
George A. Harrop

1. The oxygen content of venous and of arterial blood from fifteen essentially normal individuals at rest in bed has been determined. 2. The percentage saturation of the arterial blood has varied between 100 and 94.3. The average is 95.5 per cent. 3. The oxygen consumption has varied between 2.6 and 8.3 volumes per cent. 4. The oxygen content and the percentage saturation of arterial blood taken at close intervals from three different peripheral arteries of a normal individual have shown values agreeing within the limits of error. Analyses of the blood gases of a normal individual, at rest and after exercise, have shown a lowering of the percentage oxygen saturation of the arterial blood and a diminished carbon dioxide content after exercise. 5. In three persons with severe anemia the saturation of the arterial blood has not differed from the normal. Very low absolute values were found for the oxygen content of the venous blood, but the normal oxygen consumption has been maintained. 6. The carbon dioxide content of the arterial blood from ten normal individuals has varied between 54.7 and 44.6 volumes per cent. That of the venous blood has varied between 60.4 and 48.3 volumes per cent. 7. No deviations from the normal values for oxygen and carbon dioxide were found in venous and arterial blood from cardiac patients without arrhytiunias, well compensated, and at rest in bed. 8. A series of determinations has been made upon nine cardiac patients with varying degrees of decompensation. The percentage oxygen saturation of the arterial blood on admission was abnormally low in seven of these cases. With the return to compensation and with the clearing up of pulmonary symptoms, the percentage saturation of the arterial blood returned to normal in four of them. 9. In a case of long standing mitral endocarditis with auricular fibrillation it remained low over a period of I month of observation. 10. In a case of chronic myocarditis secondary to emphysema and chronic bronchitis, it remained low over the period of observation. 11. Normal values for the percentage saturation of the arterial blood were found in two individuals with decompensated aortic disease but without physical signs of extensive pulmonary involvement. 12. The oxygen consumption tended to be high in individuals with cardiac disease during the periods of marked decompensation and to be lower as compensation was regained. 13. The data presented indicate that at least in many circulatory diseases during decompensation, particularly when there are physical signs of pulmonary congestion, there is a disturbance of the pulmonary exchange, as indicated by the lowering of the percentage saturation of the arterial blood with oxygen.


1929 ◽  
Vol 6 (4) ◽  
pp. 340-349 ◽  
Author(s):  
ALFRED C. REDFIELD ◽  
ROBERT GOODKIND

1. The oxygen and carbon-dioxide content of the arterial and venous blood of the squid, Loligo pealei, have been measured. 2. Using a nomographic method of analysis it is shown that the reciprocal effects of oxygen and carbon dioxide upon the respiratory properties of squid haemocyanin account for one-third of the respiratory exchange. 3. The venous blood is estimated to be 0.13 pH unit more acid than the arterial blood. 4. Death from asphyxiation occurs when the oxygen and carbon-dioxide pressures are such that the arterial blood can combine with only 0.5 to 1.5 volumes per cent, oxygen. Carbon dioxide exerts no toxic effect except through its influence on the oxygenation of the blood. 5. The haemocyanin of the blood is of vital necessity to the squid, because the amount of oxygen which can be physically dissolved in blood is less than the amount which is necessary for the maintenance of life.


Renal Failure ◽  
2013 ◽  
Vol 36 (1) ◽  
pp. 145-146
Author(s):  
Fatih Bulucu ◽  
Mustafa Çakar ◽  
Ömer Kurt ◽  
Fatih Yeşildal ◽  
Hakan Şarlak

1913 ◽  
Vol 18 (1) ◽  
pp. 7-17 ◽  
Author(s):  
Francis W. Peabody

In most cases of uncomplicated lobar pneumonia the decrease of respiratory surface is completely compensated for, and the oxygen content of the blood is within normal limits. Occasional cases of uncomplicated pneumonia have an oxygen content of the venous blood which is below normal. In the two cases reported here, this was associated with a carbon dioxide content of the blood which was higher than normally, and the condition was apparently due to an interference with the respiratory exchange of gases. In the terminal stage of the fatal cases of pneumonia in which death does not occur with great suddenness, there is often a progressive diminution in the oxygen content of the blood. Synchronous with this is a progressive decrease in the oxygen-combining capacity of the blood. These changes are usually seen in patients in whom an intense bacteremia has developed and are analogous to those found in the arterial blood of infected rabbits, and to those resulting from the growth of the pneumococcus in blood in vitro. In all three conditions there is probably a change of oxyhemoglobin to methemoglobin. This change of the hemoglobin molecule, so that it no longer takes up and gives off oxygen readily, is probably a factor in the immediate cause of death in many cases of pneumonia.


1981 ◽  
Vol 50 (1) ◽  
pp. 45-54 ◽  
Author(s):  
E. A. Phillipson ◽  
J. Duffin ◽  
J. D. Cooper

We examined the dependence of respiratory rhythm generation on the rate of CO2 production (VCO2) in six awake sheep using a venous-to-venous extracorporeal perfusion circuit that included two carbon dioxide membrane lungs (CDML) designed to facilitate the removal of CO2 from blood. As progressively greater proportions of the resting VCO2, of the sheep were removed from the venous blood by the CDML, there were proportional reductions in pulmonary CO2 excretion and in minute volume of ventilation (VE); when CO2 was removed by the CDML at a rate equal to its metabolic production by the sheep, VE fell to zero, with normal values of arterial PCO2, pH, and PO2. The results indicate that effective respiratory rhythm generation is critically dependent on stimuli related to VCO2.


1966 ◽  
Vol 23 (6) ◽  
pp. 783-795 ◽  
Author(s):  
Edgar C. Black ◽  
Glenville T. Manning ◽  
Koichiro Hayashi

The effects of severe muscular exercise were studied in [Formula: see text]-year-old rainbow trout (Salmo gairdneri). Changes in the oxygen and carbon dioxide content of blood taken from the heart together with alterations in blood levels of pyruvate and lactate were followed in 14 separate conditions. Observations were also made on fish swimming steadily in a rotating annulus.


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