scholarly journals Genomewide Search for Type 2 Diabetes–Susceptibility Genes in French Whites: Evidence for a Novel Susceptibility Locus for Early-Onset Diabetes on Chromosome 3q27-qter and Independent Replication of a Type 2–Diabetes Locus on Chromosome 1q21–q24

2000 ◽  
Vol 67 (6) ◽  
pp. 1470-1480 ◽  
Author(s):  
Nathalie Vionnet ◽  
El Habib Hani ◽  
Sophie Dupont ◽  
Sophie Gallina ◽  
Stephan Francke ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Early Onset ◽  
Susceptibility Genes ◽  
Susceptibility Locus ◽  
Diabetes Susceptibility ◽  
Onset Diabetes ◽  
Independent Replication ◽  
Chromosome 1Q21

scholarly journals Linkage and Association Mapping of a Chromosome 1q21-q24 Type 2 Diabetes Susceptibility Locus in Northern European Caucasians

Diabetes ◽  
2004 ◽  
Vol 53 (2) ◽  
pp. 492-499 ◽  
Author(s):  
S. K. Das ◽  
S. J. Hasstedt ◽  
Z. Zhang ◽  
S. C. Elbein
Keyword(s):  
Type 2 Diabetes ◽  
Association Mapping ◽  
Susceptibility Locus ◽  
Diabetes Susceptibility ◽  
Northern European ◽  
Chromosome 1Q21

Type 2 Diabetes Susceptibility Genes on Chromosome 1q21–24

2008 ◽  
Vol 72 (2) ◽  
pp. 163-169 ◽  
Author(s):  
S. J. Hasstedt ◽  
W. S. Chu ◽  
S. K. Das ◽  
H. Wang ◽  
S. C. Elbein
Keyword(s):  
Type 2 Diabetes ◽  
Susceptibility Genes ◽  
Diabetes Susceptibility ◽  
Chromosome 1Q21

scholarly journals A Genome-Wide Scan in Type 2 Diabetes Mellitus Provides Independent Replication of a Susceptibility Locus on 18p11 and Suggests the Existence of Novel Loci on 2q12 and 19q13

2003 ◽  
Vol 88 (5) ◽  
pp. 2223-2230 ◽  
Author(s):  
J. H. O. van Tilburg ◽  
L. A. Sandkuijl ◽  
E. Strengman ◽  
H. van Someren ◽  
C. A. E. Rigters-Aris ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Susceptibility Locus ◽  
Genome Wide ◽  
A Genome ◽  
Independent Replication ◽  
Genome Wide Scan

scholarly journals Genomewide Search for Type 2 Diabetes Susceptibility Genes in Four American Populations

2000 ◽  
Vol 66 (6) ◽  
pp. 1871-1881 ◽  
Author(s):  
Margaret Gelder Ehm ◽  
Maha C. Karnoub ◽  
Hakan Sakul ◽  
Kirby Gottschalk ◽  
Donald C. Holt ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Susceptibility Genes ◽  
Diabetes Susceptibility

scholarly journals Search for type 2 diabetes susceptibility genes on chromosomes 1q, 3q and 12q

2008 ◽  
Vol 53 (4) ◽  
pp. 314-324 ◽  
Author(s):  
F. Takeuchi ◽  
Y. Ochiai ◽  
M. Serizawa ◽  
K. Yanai ◽  
N. Kuzuya ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Susceptibility Genes ◽  
Diabetes Susceptibility

Molecular and phenotypic characteristics of maturity-onset diabetes of the young compared with early onset type 2 diabetes in China

2015 ◽  
Vol 7 (6) ◽  
pp. 858-863 ◽  
Author(s):  
Manna Zhang ◽  
Jiao Jiao Zhou ◽  
Wenjie Cui ◽  
Yan Li ◽  
Peng Yang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Early Onset ◽  
Maturity Onset Diabetes ◽  
Phenotypic Characteristics ◽  
Onset Type ◽  
Onset Diabetes

scholarly journals Migration and DNA methylation: a comparison of methylation patterns in type 2 diabetes susceptibility genes between indians and europeans

2013 ◽  
Vol 2 (1) ◽  
pp. 6 ◽  
Author(s):  
Hannah R Elliott ◽  
Gagandeep K Walia ◽  
Aparna Duggirala ◽  
Alix Groom ◽  
S. Umakar Reddy ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Dna Methylation ◽  
Susceptibility Genes ◽  
Diabetes Susceptibility ◽  
Methylation Patterns

scholarly journals Expression profiling of putative type 2 diabetes susceptibility genes in human islets and in rat beta cell lines

2013 ◽  
Vol 03 (01) ◽  
pp. 27-32
Author(s):  
Faer Morrison ◽  
Jonathan Locke ◽  
Anna Murray ◽  
Lorna W. Harries
Keyword(s):  
Type 2 Diabetes ◽  
Beta Cell ◽  
Cell Lines ◽  
Expression Profiling ◽  
Susceptibility Genes ◽  
Human Islets ◽  
Diabetes Susceptibility

Early-Onset Subgroup of Type 2 Diabetes and Risk of Dementia, Alzheimer’s disease and Stroke: A Cohort Study

2021 ◽  
pp. 1-6
Author(s):  
K. Wang ◽  
H. Liu
Keyword(s):  
Type 2 Diabetes ◽  
Early Onset ◽  
Glycemic Status ◽  
Community Based ◽  
Diabetes Onset ◽  
Onset Diabetes ◽  
Heart Study ◽  
Increased Risk ◽  
Onset Of Diabetes

BACKGROUND: This study aimed to assess the relation of early-onset type 2 diabetes (age<55years) versus later in life to the risk of dementia, Alzheimer Disease (AD) dementia and stroke. Methods: This study was based on the Framingham Heart Study Offspring cohort (FHS-OS) which is a community-based prospective cohort. Glycemic status was ascertained at serial examinations over six decades among participants who initially did not have diabetes. Surveillance for incident events including dementia and stroke has been continued for approximately 30 years. Results: At baseline, there were 142 (5%) subjects with onset of diabetes prior to age 55 years, 172 (6%) subjects with 55-64 years, 349 (11%) subjects over 65 years and 2389 (78%) subjects without diabetes. The risk of dementia, AD and stroke increased with decreasing age of diabetes onset (P<0.05, for trend). Compared with never developing diabetes, early-onset diabetes conferred a higher risk of all dementia, AD dementia and stroke [HR 2.86(1.16-5.51) for dementia; HR 2.42(1.63-4.33) for AD; HR 2.85(1.37-3.98) for stroke]. Whereas later-onset diabetes was only associated with greater risk for stroke, neither dementia nor AD. Conclusion: Early-onset diabetes was stronger associated with an increased risk of all dementia, AD dementia and stroke than later-onset.

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