Educational Planning in a Decentralised System: The Papua New Guinean Experience. Mark Bray

1985 ◽  
Vol 29 (4) ◽  
pp. 568-570
Author(s):  
Philip Foster
Keyword(s):  
Educational Planning ◽  
Papua New Guinean ◽  
Decentralised System

Educational Planning in a Decentralised System.

1985 ◽  
Vol 58 (4) ◽  
pp. 748
Author(s):  
Edward R. Beauchamp ◽  
Mark Bray
Keyword(s):  
Educational Planning ◽  
Decentralised System

An Assessment of the Distribution of Public-Sector Educational Investment in Pakistan: 1970-71 - 1982-83 (Review Article, Note, Comment)

1986 ◽  
Vol 25 (2) ◽  
pp. 175-192
Author(s):  
Shahrukh Rafi Khan ◽  
Naushin Mahmood ◽  
Rehana Siddiqui
Keyword(s):  
Public Sector ◽  
Primary Education ◽  
Resource Constraints ◽  
Educational Planning ◽  
Review Article ◽  
Planning Theory ◽  
Limited Resources ◽  
Educational Investment ◽  
User Charges ◽  
Partial Success

Planning documents for the Seventies emphasized the importance of primary education and the curtailment of the mushrooming growth at the higher level. Our review suggests that this policy has had only partial success in implementation. Viewed in the context of educational planning theory and the evidence available for Pakistan, the policy is found to be sound. While the benefits of a correct distribution of investment within the educational sector are self-evident, resource constraints have been leading to an overall underinvestment in the educational sector. We show that Pakistan's public sector education is highly subsidized and so to supplement the limited resources devoted to it, we recommend, as a possible solution, a selective application of user charges.

scholarly journals Sequence analysis of Plasmodium vivax Duffy binding proteins reveals the presence of unique haplotypes and diversifying selection in Ethiopian isolates

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Lemu Golassa ◽  
Alebachew Messele ◽  
Eniyou Cheryll Oriero ◽  
Alfred Amambua-Ngwa
Keyword(s):  
Vaccine Development ◽  
Haplotype Diversity ◽  
Sri Lankan ◽  
Duffy Binding Protein ◽  
Synonymous Mutations ◽  
South Korean ◽  
Blood Stage Infection ◽  
Vaccine Approach ◽  
Papua New Guinean ◽  
Reference Haplotype

Abstract Background Red blood cell invasion by the Plasmodium vivax merozoite requires interaction between the Duffy antigen receptor for chemokines (DARC) and the P. vivax Duffy-binding protein II (PvDBPII). Given that the disruption of this interaction prevents P. vivax blood-stage infection, a PvDBP-based vaccine development has been well recognized. However, the polymorphic nature of PvDBPII prevents a strain transcending immune response and complicates attempts to design a vaccine. Methods Twenty-three P. vivax clinical isolates collected from three areas of Ethiopia were sequenced at the pvdbpII locus. A total of 392 global pvdbpII sequences from seven P. vivax endemic countries were also retrieved from the NCBI archive for comparative analysis of genetic diversity, departure from neutrality, linkage disequilibrium, genetic differentiation, PvDBP polymorphisms, recombination and population structure of the parasite population. To establish a haplotype relationship a network was constructed using the median joining algorithm. Results A total of 110 variable sites were found, of which 44 were parsimony informative. For Ethiopian isolates there were 12 variable sites of which 10 were parsimony informative. These parsimony informative variants resulted in 10 nonsynonymous mutations. The overall haplotype diversity for global isolates was 0.9596; however, the haplotype diversity was 0.874 for Ethiopia. Fst values for genetic revealed Ethiopian isolates were closest to Indian isolates as well as to Sri Lankan and Sudanese isolates but further away from Mexican, Papua New Guinean and South Korean isolates. There was a total of 136 haplotypes from the 415 global isolates included for this study. Haplotype prevalence ranged from 36.76% to 0.7%, from this 74.2% were represented by single parasite isolates. None of the Ethiopian isolates grouped with the Sal I reference haplotype. From the total observed nonsynonymous mutations 13 mapped to experimentally verified epitope sequences. Including 10 non-synonymous mutations from Ethiopia. However, all the polymorphic regions in Ethiopian isolates were located away from DARC, responsible for junction formation. Conclusion The results of this study are concurrent with the multivalent vaccine approach to design an effective treatment. However, the presence of novel haplotypes in Ethiopian isolates that were not shared by other global sequences warrant further investigation.

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