scholarly journals Vaccination of Dogs againstEchinococcus granulosus,the Cause of Cystic Hydatid Disease in Humans

2006 ◽  
Vol 194 (7) ◽  
pp. 966-974 ◽  
Author(s):  
Wenbao Zhang ◽  
Zhuangzhi Zhang ◽  
Baoxin Shi ◽  
Jun Li ◽  
Hong You ◽  
...  
Keyword(s):  
Hydatid Disease ◽  
Cystic Hydatid Disease ◽  
Cystic Hydatid

Cystic hydatid disease (Echinococcus granulosus)

2020 ◽  
pp. 1529-1533
Author(s):  
Pedro L. Moro ◽  
Hector H. Garcia ◽  
Armando E. Gonzalez
Keyword(s):  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Imaging Techniques ◽  
Clinical Manifestations ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Cystic Hydatid Disease ◽  
Control Programmes ◽  
Domestic Livestock ◽  
Cystic Hydatid

Cystic hydatid disease, caused by Echinococcus granulosus, is a zoonotic disease principally transmitted between dogs and domestic livestock, particularly sheep. Humans are infected when they ingest tapeworm eggs, with disease occurring in most parts of the world where sheep are raised and dogs are used to herd livestock. The most common clinical manifestations are cysts in the liver (typically presenting with hepatomegaly) and/or lung (presenting with cough, haemoptysis, and dyspnoea). Diagnosis is usually made on the basis of serological tests in combination with imaging techniques. Treatment options include surgery, chemotherapy with anthelminthic agents, or—for liver cysts—PAIR (puncture–aspiration–injection–reaspiration). Echinococcosis is a major public health problem in several countries. Control programmes have been aimed at educating dog owners to prevent their animals from having access to infected offal. Vaccines against sheep hydatidosis and the dog tapeworm stage are promising alternatives.

scholarly journals Oxfendazole Treatment for Cystic Hydatid Disease in Naturally Infected Animals

1998 ◽  
Vol 42 (3) ◽  
pp. 601-605 ◽  
Author(s):  
Ronald E. Blanton ◽  
Timothy M. Wachira ◽  
Eberhard E. Zeyhle ◽  
Ernest M. Njoroge ◽  
Japheth K. Magambo ◽  
...  
Keyword(s):  
Hydatid Disease ◽  
Cyst Wall ◽  
Inflammatory Cells ◽  
Chemotherapeutic Agents ◽  
Postmortem Examination ◽  
Cystic Hydatid Disease ◽  
Adventitial Layer ◽  
Cystic Hydatid

ABSTRACT Few chemotherapeutic agents are available for the medical management of hydatid disease caused by the parasite Echinococcus granulosus. In order to test the potential of oxfendazole for the treatment of infection with this parasite, nine infected goats and four sheep were given oxfendazole twice weekly at a dose of 30 mg/kg of body weight for 4 weeks and monitored by ultrasound for an additional 4 weeks. Efficacy was finally evaluated by postmortem examination, including determination of protoscolex viability and cyst wall histology. In treated animals, protoscolices were dead or absent in 97% of cysts from oxfendazole-treated animals compared to 28% of cysts from untreated control animals. On postmortem examination, 53% of cysts from treated animals were found to be grossly degenerate. A sample of those cysts that appeared potentially viable all demonstrated evidence of severe damage to the cyst wall. By light microscopy, cysts showed severe disorganization of the adventitial layer with invasion of inflammatory cells and in some cases frank necrosis with no apparent adventitial layer. The follow-up period for assessment of the drug’s ability to cause complete degeneration and resorption of cysts was relatively short. This study, however, indicates that oxfendazole is at least as effective as and is easier to administer than albendazole for the treatment of hydatid disease.

Cystic Hydatid Disease: Current Trends in Diagnosis and Management

Surgery Today ◽  
2004 ◽  
Vol 34 (12) ◽  
pp. 987-996 ◽  
Author(s):  
Iskender Sayek ◽  
M. Bulent Tirnaksiz ◽  
Riza Dogan
Keyword(s):  
Hydatid Disease ◽  
Cystic Hydatid Disease ◽  
Diagnosis And Management ◽  
Current Trends ◽  
Cystic Hydatid

Differential immunodiagnosis between cystic hydatid disease and other cross-reactive pathologies.

1999 ◽  
Vol 60 (2) ◽  
pp. 193-198 ◽  
Author(s):  
D Poretti ◽  
C Zuercher ◽  
B Gottstein ◽  
F Grimm ◽  
M Pfister ◽  
...  
Keyword(s):  
Hydatid Disease ◽  
Cystic Hydatid Disease ◽  
Cystic Hydatid

Cystic hydatid disease of the gallbladder

2012 ◽  
Vol 23 (6) ◽  
pp. 825-826 ◽  
Author(s):  
Metin ERTEM ◽  
Erman AYTAC ◽  
Zekeriya KARADUMAN
Keyword(s):  
Hydatid Disease ◽  
Cystic Hydatid Disease ◽  
Cystic Hydatid

Cestode vaccines: origins, current status and future prospects

Parasitology ◽  
2006 ◽  
Vol 133 (S2) ◽  
pp. S27-S42 ◽  
Author(s):  
M. W. LIGHTOWLERS
Keyword(s):  
Hydatid Disease ◽  
Taenia Solium ◽  
Economic Value ◽  
Scale Up ◽  
Current Status ◽  
Scale Production ◽  
Cystic Hydatid Disease ◽  
Commercial Scale ◽  
Zoonotic Parasites ◽  
Cystic Hydatid

Recombinant vaccines have been developed which are highly effective in preventing infection with Taenia ovis in sheep, Taenia saginata in cattle, Taenia solium in pigs and Echinococcus granulosus in livestock animals. T. ovis and T. saginata are economically significant parasites and the commercial success or otherwise of vaccines against them will rely on their economic value. E. granulosus and T. solium are zoonotic parasites that cause cystic hydatid disease and neurocysticercosis, respectively, in humans. Vaccines against these parasites have been developed to assist with the control of transmission of the human diseases rather than for prevention of infections in livestock per se. Regions of high prevalence for cystic hydatid disease and neurocysticercosis occur primarily in the developing world. As a consequence, vaccines against them are of little or no commercially interest – they are Orphan Vaccines. Lack of commercial interest in these vaccines has made public sector support for their development necessary well beyond the research phase trough into completion of commercial scale-up and other more commercially-related assessments. Practical use of the vaccines will require commercial-scale production according to international manufacturing standards. Identifying partners and support in this endeavour is now of prime importance in efforts to achieve the potential of these vaccines as new tools for the control of cystic hydatid disease and neurocysticercosis.

A high prevalence of cystic hydatid disease in North Africa

1997 ◽  
Vol 91 (8) ◽  
pp. 957-959 ◽  
Author(s):  
M. K. Shambesh ◽  
P. S. Craig ◽  
M. M. Ibrahem ◽  
A. M. Gusbi ◽  
E. F. Echtuish
Keyword(s):  
Hydatid Disease ◽  
North Africa ◽  
Cystic Hydatid Disease ◽  
High Prevalence ◽  
Cystic Hydatid
Sign in / Sign up

Export Citation Format

Share Document