The effects of delays in radiotherapy treatment on tumour control

2002 ◽  
Vol 48 (2) ◽  
pp. 139-155 ◽  
Author(s):  
R M Wyatt ◽  
A H Beddoe ◽  
R G Dale
Keyword(s):  
Tumour Control ◽  
Radiotherapy Treatment

Nuklearmedizin trifft Strahlentherapie

2010 ◽  
Vol 49 (S 01) ◽  
pp. S11-S15
Author(s):  
C. Schütze ◽  
M. Krause ◽  
A. Yaromina ◽  
D. Zips ◽  
M. Baumann
Keyword(s):  
Nuclear Medicine ◽  
Radiation Oncology ◽  
External Beam Radiotherapy ◽  
Biological Knowledge ◽  
Important Research ◽  
Tumour Control ◽  
Research Areas ◽  
Normal Tissue Damage ◽  
Local Tumour Control ◽  
Local Tumour

SummaryRadiobiological and cell biological knowledge is increasingly used to further improve local tumour control or to reduce normal tissue damage after radiotherapy. Important research areas are evolving which need to be addressed jointly by nuclear medicine and radiation oncology. For this differences of the biological distribution of diagnostic and therapeutic nuclides compared with the more homogenous dose-distribution of external beam radiotherapy have to be taken into consideration. Examples for interdisciplinary biology-based cancer research in radiation oncology and nuclear medicine include bioimaging of radiobiological parameters characterizing radioresistance, bioimage-guided adaptive radiotherapy, and the combination of radiotherapy with molecular targeted drugs.

scholarly journals Sequential targeting of PI3Kδ and LAG3 as an effective anti-cancer approach

2021 ◽  
Author(s):  
Sarah N. Lauder ◽  
Bart Vanhaesebroeck ◽  
Awen Gallimore
Keyword(s):  
Immune Checkpoint ◽  
Immune Checkpoint Blockade ◽  
Solid Tumours ◽  
Checkpoint Blockade ◽  
Tumour Control ◽  
Anti Cancer ◽  
Clinical Models

SummaryEmerging studies have demonstrated the potential of PI3Kδ blockade as an immunotherapy for solid tumours. In pre-clinical models, we recently demonstrated that anti-LAG3 immune checkpoint blockade vastly potentiated PI3Kδ-based immunotherapy, enabling successful tumour control in all treated mice.

scholarly journals A comparison of two methodologies for radiotherapy treatment plan optimization and QA for clinical trials

2021 ◽  
Vol 22 (10) ◽  
pp. 329-337
Author(s):  
Huaizhi Geng ◽  
Tawfik Giaddui ◽  
Chingyun Cheng ◽  
Haoyu Zhong ◽  
Samuel Ryu ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Treatment Plan ◽  
Plan Optimization ◽  
Treatment Plan Optimization ◽  
Radiotherapy Treatment
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