Optimization of tumour control probability for heterogeneous tumours in fractionated radiotherapy treatment protocols

2004 ◽  
Vol 49 (3) ◽  
pp. 407-424 ◽  
Author(s):  
D Levin-Plotnik ◽  
R J Hamilton
Keyword(s):  
Treatment Protocols ◽  
Fractionated Radiotherapy ◽  
Tumour Control ◽  
Tumour Control Probability ◽  
Radiotherapy Treatment

2046 Interruptions in fractionated radiotherapy: incidence, causes and impact in tumour control probability

2009 ◽  
Vol 7 (2) ◽  
pp. 164-165
Author(s):  
M.B. Rios Pozo ◽  
R.E. Pacios ◽  
D. Guirado ◽  
I. Castillo ◽  
M.T. Delgado ◽  
...  
Keyword(s):  
Fractionated Radiotherapy ◽  
Tumour Control ◽  
Tumour Control Probability

scholarly journals Tumour control probability after Ruthenium-106 brachytherapy for choroidal melanomas

2020 ◽  
Vol 59 (8) ◽  
pp. 918-925 ◽  
Author(s):  
Charlotte A. Espensen ◽  
Ane L. Appelt ◽  
Lotte S. Fog ◽  
Juliette Thariat ◽  
Anita B. Gothelf ◽  
...  
Keyword(s):  
Tumour Control ◽  
Tumour Control Probability ◽  
Ruthenium 106 Brachytherapy ◽  
Choroidal Melanomas

Tumour control probability of a UK cohort of lung SABR patients

2020 ◽  
pp. 1-3
Author(s):  
J. E. Marsden
Keyword(s):  
The Other ◽  
Stereotactic Ablative Radiotherapy ◽  
Linear Quadratic ◽  
Planning Techniques ◽  
Tumour Control ◽  
Tumour Control Probability ◽  
The Uk

Abstract Aims: The aim of this work is to report on the tumour control probability (TCP) of a UK cohort of lung stereotactic ablative radiotherapy patients (n = 198) for a range of dose and fractionations common in the UK. Materials and methods: TCP values for 3 (54 Gy), 5 (55 and 60 Gy) and 8 (50 Gy) fraction (#) schemes were calculated with the linear-quadratic Marsden TCP model using the Biosuite software. Results: TCP values of 100% were computed for the 3 # and for 5 # (α/β = 10 Gy) cohorts; reduced to 99% (range 97–100) for the 5 # cohort only when an α/β of 20 Gy was used. The average TCP value for the 50 Gy in 8 # regime was 97% (range 92–99, α/β = 10 Gy) and 64% (range 48–79, α/β = 20 Gy). Statistical significant differences were observed between the α/β of 10 Gy versus 20 Gy groups and between all data grouped by fraction. Conclusion: TCPs achievable with current planning techniques in the UK have been presented. The ultra-conservative 50 Gy in 8 # scheme returns a significantly lower TCP than the other regimes.

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