Electron density measurement with dual-energy x-ray CT using synchrotron radiation

2003 ◽  
Vol 48 (5) ◽  
pp. 673-685 ◽  
Author(s):  
Masami Torikoshi ◽  
Takanori Tsunoo ◽  
Makoto Sasaki ◽  
Masahiro Endo ◽  
Yutaka Noda ◽  
...  
2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Kuo Men ◽  
Jian-Rong Dai ◽  
Ming-Hui Li ◽  
Xin-Yuan Chen ◽  
Ke Zhang ◽  
...  

Purpose. To develop a dual energy imaging method to improve the accuracy of electron density measurement with a cone-beam CT (CBCT) device.Materials and Methods. The imaging system is the XVI CBCT system on Elekta Synergy linac. Projection data were acquired with the high and low energy X-ray, respectively, to set up a basis material decomposition model. Virtual phantom simulation and phantoms experiments were carried out for quantitative evaluation of the method. Phantoms were also scanned twice with the high and low energy X-ray, respectively. The data were decomposed into projections of the two basis material coefficients according to the model set up earlier. The two sets of decomposed projections were used to reconstruct CBCT images of the basis material coefficients. Then, the images of electron densities were calculated with these CBCT images.Results. The difference between the calculated and theoretical values was within 2% and the correlation coefficient of them was about 1.0. The dual energy imaging method obtained more accurate electron density values and reduced the beam hardening artifacts obviously.Conclusion. A novel dual energy CBCT imaging method to calculate the electron densities was developed. It can acquire more accurate values and provide a platform potentially for dose calculation.


2003 ◽  
Vol 50 (5) ◽  
pp. 1678-1682 ◽  
Author(s):  
T. Tsunoo ◽  
M. Torikoshi ◽  
M. Sasaki ◽  
M. Endo ◽  
N. Yagi ◽  
...  
Keyword(s):  

2010 ◽  
Author(s):  
Yukino Imura ◽  
Hisashi Morii ◽  
Akifumi Koike ◽  
Takaharu Okunoyama ◽  
Yoichiro Neo ◽  
...  

Author(s):  
Stefan Mebs ◽  
Anja Lüth ◽  
Wolfgang Löwe ◽  
Carsten Paulmann ◽  
Peter Luger

AbstractThe electron density (ED) of a substituted 4-(indol-3-yl)-quinazoline, a newly developed anti-cancer drug, was determined from a high resolution X-ray data set measured at 100 K using synchrotron radiation. Because the structure contains a chlorine atom, which has a diffuse outer electron shell and is therefore beyond standard modeling, the influence of the model on the bond topological and atomic properties was studied following Bader's approach of ‘Atoms In Molecules’ (AIM). The expansion/contraction parameters


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