Noise generated by control valves in power generation, chemical and petrochemical plants must be predictable so that proper design measures can be taken to conform to OSHA’s noise regulation. Currently available noise prediction methods are empirically based and not sufficiently accurate. The method proposed is based on jet noise theory for both subcritical and choked conditions, duct acoustics theory in terms of higher order mode generation and propagation, and the theory of acoustics-structure interaction in the development of the transmission loss values for the pipe. One third octave values are calculated over the audio spectrum by incorporating spectral aspects of noise generation, propagation, transmission, and radiation. The predicted values of noise for several size cage globe valves over wide pressure ranges compare well with measured results by two prominent valve manufacturers. The method, at present, is restricted to conventional valve styles, as opposed to the special low noise valve types with their very complicated orificial elements.