scholarly journals Teaching convex Lens materials with a PIMCA model

2021 ◽  
Vol 1968 (1) ◽  
pp. 012037
Author(s):  
R Koming ◽  
C Poluakan ◽  
P M Silangen ◽  
A H Mondolang ◽  
J Rende
Keyword(s):  
Convex Lens

scholarly journals Single-cell analysis for drug development using convex lens-induced confinement imaging

BioTechniques ◽  
2019 ◽  
Vol 67 (5) ◽  
pp. 210-217 ◽  
Author(s):  
Ndeye Khady Thiombane ◽  
Nicolas Coutin ◽  
Daniel Berard ◽  
Radin Tahvildari ◽  
Sabrina Leslie ◽  
...  
Keyword(s):  
Single Cell ◽  
Drug Response ◽  
Drug Exposure ◽  
Cellular Proliferation ◽  
New Technologies ◽  
Detection Sensitivity ◽  
Yeast Cells ◽  
Sample Population ◽  
Phenotypic Analysis ◽  
Convex Lens

New technologies have powered rapid advances in cellular imaging, genomics and phenotypic analysis in life sciences. However, most of these methods operate at sample population levels and provide statistical averages of aggregated data that fail to capture single-cell heterogeneity, complicating drug discovery and development. Here we demonstrate a new single-cell approach based on convex lens-induced confinement (CLiC) microscopy. We validated CLiC on yeast cells, demonstrating subcellular localization with an enhanced signal-to-noise and fluorescent signal detection sensitivity compared with traditional imaging. In the live-cell CLiC assay, cellular proliferation times were consistent with flask culture. Using methotrexate, we provide drug response data showing a fivefold cell size increase following drug exposure. Taken together, CLiC enables high-quality imaging of single-cell drug response and proliferation for extended observation periods.

Fabrication of convex lens-shaped polymer particles by tuning the interfacial interaction

2017 ◽  
Vol 1 (3) ◽  
pp. 507-511 ◽  
Author(s):  
Jiangping Xu ◽  
Yi Yang ◽  
Ke Wang ◽  
Yuqing Wu ◽  
Jintao Zhu
Keyword(s):  
Block Copolymers ◽  
Small Molecules ◽  
Interfacial Interaction ◽  
Polymer Particles ◽  
Emulsion Droplets ◽  
Convex Lens ◽  
Cylindrical Domains

With the addition of small molecules to emulsion droplets containing block copolymers, anisotropic convex lens-like particles with hexagonally stacked cylindrical domains can be readily achieved by using a single surfactant to create a neutral interface for both blocks.

A Novel High Concentration Fresnel Lens as a Solar Concentrator

2021 ◽  
pp. 1-29
Author(s):  
Kuldeep Awasthi ◽  
Desireddy Shashidhar Reddy ◽  
Mohd. Kaleem Khan
Keyword(s):  
Optical Axis ◽  
Spherical Aberration ◽  
Spherical Surface ◽  
Fresnel Lens ◽  
High Concentration ◽  
Aperture Diameter ◽  
Convex Lens ◽  
Flat Base ◽  
Fresnel Lenses ◽  
Outer Vertex

Abstract This paper describes the design methodology for a novel Fresnel lens. The original Fresnel lens is obtained from a plano-convex lens, whose spherical surface is split into a number of divisions (called facets), collapsed onto the flat base. Thus, all the facets of the original Fresnel lens have the same radius as that of the plano-convex lens. The proposed design aims to achieve better ray concentration and reduced spherical aberration than the original Fresnel lens by constructing spherical facets with unequal radii. The centers and radii of facets are constrained so that the ray refracted from the bottom vertex of each facet on one side of the optical axis and the ray refracted from the outer vertex of the corresponding facet on the other side of the optical axis must intersect at the focal plane. The proposed lens design has resulted in a 275% gain in the concentration ratio and a 72.5% reduction in the spherical aberration compared to the original lens of the same aperture diameter and number of facets. The performance of both novel and original Fresnel lenses when used as solar concentrators with a conical coil receiver is evaluated. The novel Fresnel lens led to increased heat gain and resulted in a compact solar collector design.

Development of a platform for single cell genomics using convex lens-induced confinement

Lab on a Chip ◽  
2015 ◽  
Vol 15 (14) ◽  
pp. 3013-3020 ◽  
Author(s):  
Sara Mahshid ◽  
Mohammed Jalal Ahamed ◽  
Daniel Berard ◽  
Susan Amin ◽  
Robert Sladek ◽  
...  
Keyword(s):  
Single Cell ◽  
Base Pair ◽  
Single Cell Analysis ◽  
Lab On A Chip ◽  
Cell Analysis ◽  
Next Generation ◽  
Single Cell Genomics ◽  
Convex Lens ◽  
Genomic Dnas

We present a lab-on-a-chip for the next generation of single-cell genomics, performing full-cycle single-cell analysis by demonstrating mega-base pair genomic DNAs in nanochannels extracted in situ.

Diffusive dynamics of charged nanoparticles in convex lens-induced confinement

Soft Matter ◽  
2022 ◽  
Author(s):  
Emmanuel Hitimana ◽  
Brittany K. Roopnarine ◽  
Svetlana Morozova
Keyword(s):  
Confined Geometries ◽  
Convex Lens ◽  
Diffusive Dynamics ◽  
Charged Nanoparticles ◽  
Hydrodynamic Effects

Hydrodynamic effects influence the dynamics of nanoparticles in confined geometries.

Curved Projection Integral Imaging Using an Additional Large-Aperture Convex Lens for Viewing Angle Improvement

ETRI Journal ◽  
2009 ◽  
Vol 31 (2) ◽  
pp. 105-110 ◽  
Author(s):  
Joobong Hyun ◽  
Dong-Choon Hwang ◽  
Dong-Hak Shin ◽  
Byung-Gook Lee ◽  
Eun-Soo Kim
Keyword(s):  
Viewing Angle ◽  
Integral Imaging ◽  
Large Aperture ◽  
Convex Lens
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