scholarly journals Antioxidant and Antibacterial Activities of Several Fractions from Crescentia cujete L. Stem Bark Extract

Author(s):  
Syaefudin ◽  
D Nitami ◽  
M D M Utari ◽  
M Rafi ◽  
U Hasanah
2014 ◽  
Vol 9 (18) ◽  
pp. 826-833 ◽  
Author(s):  
B. A. Akinpelu ◽  
O. A. Igbeneghu ◽  
A. I. Awotunde ◽  
E. O. Iwalewa ◽  
O. O. Oyedapo

Author(s):  
S. Salihu ◽  
C. A. Otitolaiye ◽  
M. U. Hizbullah

Aim: This research investigated the anti-malarial and antibacterial activities of stem bark methanol extract of Frankincense tree and Kenaf leaves extract on Plasmodium falciparum parasite and against five clinically significant bacteria. Study Design: Laboratory-experimental design was used for this study. Place and Duration of Study: This study was carried out between September 2019 and November 2019 at Biochemistry and Microbiology laboratories, Sokoto State University, Sokoto, Nigeria. Methodology: The in vitro antimalarial activity test was conducted by determining the parasitemia for each sample concentration by manual counting on thin Giemsa smears after a 24-hour incubation with the extracts in order to determine the IC50 values. The antibacterial study was done using a modified agar well diffusion technique. Results: The testing revealed that methanol stem bark extract of Frankincense tree and Kenaf leaves exhibited good and potent (very good) antimalarial activities against P. falciparum respectively with IC50 values of 1.25 μg/mL and 0.16 μg/mL respectively. They also show good inhibitory activities against E.coli but slight inhibitory activities against the other pathogens tested. Conclusion: The current study indicates that extracts of these plants exhibit anti-malarial and antibacterial activities and may serve as useful sources of drugs for treatment of malaria caused by P. falciparum parasite as well as bacterial infections caused by the tested bacteria.


2020 ◽  
Vol 36 (2) ◽  
pp. 52-61
Author(s):  
D.O. Ekhuemelo ◽  
C. Ekhuemelo ◽  
E.T. Tembe

This study assessed the antibacterial properties of sawdust and stem bark of Erythrophleum suaveolens extracts on selected wood bacteria. Erythrophleum suaveolens samples were collected, dried and macerated by dissolving 1 Kg and 0.60 Kg of stem bark and sawdust respectively into 1 L of n-hexane, ethyl acetate and methanol. Sporfloxacin ciprofloxacin and cefuroxine antibiotics were used as control. The mixture was left for 24 hours then filtered and the filtrates evaporated to dryness. Qualitative phytochemical screening, zone of inhibition, minimum inhibitory and Bactericidal Concentrations (MIC/MBC) were determined according to standard methods. Tannins, steroids, saponins, glycosides, flavonoids, carbohydrates anthraquinones and alkaloids phytochemicals were present in E. suaveolens extracts. Zone of inhibition (32 – 37 mm) of antibiotics on test bacteria compared favourably with 17 – 24 mm of E. suaveolens extracts. Erythrophleum suaveolens ethyl acetate and methanol E. suaveolens extracts inhibited Staphylolococus aureus, Ralstonia solanacearum, Proteus mirabilis, Enterococcus faecium and Acidobacterium capsulatum growth at MIC of 10 mg/mL and n-hexane extracts at 20 mg/mL. At MBC of 20 mg/mL methanol stem bark extract completely killed most test bacteria. Methanol extracts were the most active extracts. The study has shown that E. suaveolens extracts can be explored in the control of plant diseases caused by test bacteria in the study. Key words: Antibacterial, E. suaveolens, extract, phytochemicals, zone of inhibition


Author(s):  
James F. Amaku ◽  
Segun A. Ogundare ◽  
Kovo G. Akpomie ◽  
Comfort M. Ngwu ◽  
Jeanet Conradie

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Camila Gabriel Kato-Schwartz ◽  
Anacharis Babeto de Sá-Nakanishi ◽  
Ana Carolina Guidi ◽  
Geferson de Almeida Gonçalves ◽  
Fernanda Giacomini Bueno ◽  
...  

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