Correlation between Wall Motion Score Index (WMSI) and Anatomical M-mode (AAM) Systolic Thickening with Functional Capacity in Heart Failure among Post-myocardial Infarction Patients

Background: There are few data on the prognostic significance of the wall motion score index compared with left ventricle ejection fraction after an acute myocardial infarction. Our objective was to compare them after the hyperacute phase. Methods: Transthoracic echocardiograms were performed in 352 consecutive patients with myocardial infarction, after the first 48 hours of admission and before hospital discharge (median 56.3 hours (48.2–83.1)). We evaluated the ability of the wall motion score index and left ventricular ejection fraction to predict the combined endpoint (mortality and rehospitalization for heart failure) as a primary objective and the independent events of the combined endpoint as a secondary objective. Results: In 80.7% of patients, the wall motion score index was high despite having an ejection fraction >40%. No patient had an ejection fraction <55% with a normal index. After a follow-up of 30.5 months (24.2–49.5), both variables were predictors of the composite endpoint and all-cause mortality ( p<0.0001), although only the wall motion score index was a predictor of readmission for heart failure ( p=0.007). By multivariate analysis, a wall motion score index >1.8 proved to be the most powerful predictor of the composite endpoint (hazard ratio: 8.5; 95% confidence interval 3.7–18.8; p<0.0001). The superiority of the wall motion score index over ejection fraction was especially significant in patients with less myocardial damage (non-ST elevation myocardial infarction, or left ventricle ejection fraction >40%). Conclusions: Both variables provide important prognostic information after a myocardial infarction. Beyond the hyperacute phase, wall motion score index is a more powerful prognostic predictor, especially in subgroups with less myocardial damage.

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Strain Echocardiography and Wall Motion Score Index Predicts Final Infarct Size in Patients With Non–ST-Segment–Elevation Myocardial Infarction

Circulation Cardiovascular Imaging ◽

10.1161/circimaging.109.910521 ◽

2010 ◽

Vol 3 (2) ◽

pp. 187-194 ◽

Cited By ~ 54

Author(s):

Christian Eek ◽

Bj�rnar Grenne ◽

Harald Brunvand ◽

Svend Aakhus ◽

Knut Endresen ◽

...

Keyword(s):

Myocardial Infarction ◽

Infarct Size ◽

Wall Motion ◽

Wall Motion Score Index ◽

St Segment Elevation ◽

Segment Elevation Myocardial Infarction ◽

St Segment ◽

Final Infarct Size ◽

Score Index ◽

Strain Echocardiography

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Wall motion score index and ejection fraction for risk stratification after acute myocardial infarction

American Heart Journal ◽

10.1016/j.ahj.2005.03.042 ◽

2006 ◽

Vol 151 (2) ◽

pp. 419-425 ◽

Cited By ~ 138

Author(s):

Jacob E. Møller ◽

Graham S. Hillis ◽

Jae K. Oh ◽

Guy S. Reeder ◽

Bernard J. Gersh ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Ejection Fraction ◽

Risk Stratification ◽

Wall Motion ◽

Wall Motion Score Index ◽

Score Index

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Abstract 16032: Determinants of Exercise Capacity Assessed Using Combined Stress Echocardiography and Cardiopulmonary Exercise Testing in Patients Treated for Acute Myocardial Infarction

Circulation ◽

10.1161/circ.142.suppl_3.16032 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Krzysztof Smarz ◽

Tomasz Jaxa-Chamiec ◽

Beata Zaborska ◽

Maciej Tysarowski ◽

Andrzej Budaj

Keyword(s):

Myocardial Infarction ◽

Stress Echocardiography ◽

Wall Motion ◽

Cardiopulmonary Exercise Testing ◽

Left Ventricular ◽

Combined Stress ◽

Wall Motion Score Index ◽

Cardiopulmonary Exercise ◽

Oxygen Difference ◽

Score Index

Introduction: Exercise capacity (EC) after acute myocardial infarction (AMI) influences prognosis, but the causes of its reduction are complex and not sufficiently studied. Methods: We prospectively enrolled consecutive patients who underwent percutaneous coronary intervention for their first AMI without residual coronary stenosis and with left ventricular ejection fraction (LVEF) > 40% more than 4 weeks after the AMI. We performed combined stress echocardiography and cardiopulmonary exercise testing (CPET-SE) using a semi-supine cycle ergometer to determine predictors of EC (peak oxygen uptake [VO 2 ]). Results: Among 81 patients (70% male, mean age 58 ± 11 years), 40% suffered AMI with ST-segment elevation (STEMI), and 60% non-STEMI, LVEF was 57 ± 7%; wall motion score index, 1.18 (IQR 1.06 - 1.31); peak VO 2 , 19.5 ± 5.4 mL/kg/min. Multivariate analysis ( Table ) revealed that parameters at peak exercise: heart rate (β = 0.17, p < 0.001), stroke volume (β = 0.09, p < 0.001), and arteriovenous oxygen difference (β = 93.51, p < 0.001) were independently positively correlated with peak VO 2 , with arteriovenous oxygen difference being its strongest contributor. At rest, left ventricular systolic and diastolic function parameters and the extent of myocardial scarring (wall motion score index) did not predict EC (p > 0.05). Conclusions: In patients treated for AMI with normal/mildly reduced LVEF, EC is associated with peak peripheral oxygen extraction as well as peak heart rate and peak stroke volume. CPET-SE is a useful tool to evaluate decreased fitness in this group.

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Correlation between Serum Galectin-3 Level with Wall Motion Score Index in Patients with ST-Segment Elevation Myocardial Infarction

IOP Conference Series Earth and Environmental Science ◽

10.1088/1755-1315/441/1/012188 ◽

2020 ◽

Vol 441 ◽

pp. 012188

Author(s):

K Halid ◽

M Aminuddin ◽

I P Dewi

Keyword(s):

Myocardial Infarction ◽

Wall Motion ◽

Wall Motion Score Index ◽

St Segment Elevation ◽

Segment Elevation Myocardial Infarction ◽

St Segment ◽

Galectin 3 ◽

Score Index

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Short early filling deceleration time on day 1 after acute myocardial infarction is associated with short and long term left ventricular remodelling

Heart ◽

10.1136/hrt.85.5.527 ◽

2001 ◽

Vol 85 (5) ◽

pp. 527-532

Author(s):

P Otašević ◽

A N Nešković ◽

Z Popović ◽

A Vlahović ◽

D Bojić ◽

...

Keyword(s):

Myocardial Infarction ◽

Ejection Fraction ◽

Wall Motion ◽

Left Ventricular ◽

Cardiac Mortality ◽

Ventricular Remodelling ◽

Wall Motion Score Index ◽

Left Ventricular Remodelling ◽

Score Index ◽

Deceleration Time

OBJECTIVETo assess the relations between early filling deceleration time, left ventricular remodelling, and cardiac mortality in an unselected group of postinfarction patients.DESIGN AND PATIENTSProspective evaluation of 131 consecutive patients with first acute myocardial infarction. Echocardiography was performed on day 1, day 2, day 3, day 7, at three and six weeks, and at three, six, and 12 months after infarction. According to deceleration time on day 1, patients were divided into groups with short (< 150 ms) and normal deceleration time (⩾ 150 ms).SETTINGTertiary care centre.RESULTSPatients with a short deceleration time had higher end systolic and end diastolic volume indices and a higher wall motion score index, but a lower ejection fraction, in the year after infarction. These patients also showed a significant increase in end diastolic (p < 0.001) and end systolic volume indices (p = 0.007) during the follow up period, while ejection fraction and wall motion score index remained unchanged. In the group with normal deceleration time, end diastolic volume index increased (p < 0.001) but end systolic volume index did not change; in addition, the ejection fraction increased (p = 0.002) and the wall motion score index decreased (p < 0.001). One year and five year survival analysis showed greater cardiac mortality in patients with a short deceleration time (p = 0.04 and p = 0.02, respectively). In a Cox model, which included initial ejection fraction, infarct location, and infarct size, deceleration time on day 1 was the only significant predictor of five year mortality.CONCLUSIONSA short deceleration time on day 1 after acute myocardial infarction can identify patients who are likely to undergo left ventricular remodelling in the following year. These patients have a higher one year and five year cardiac mortality.

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Prevalence and prognostic significance of silent myocardial ischemia in patients after myocardial infarction

Vojnosanitetski pregled ◽

10.2298/vsp0708519d ◽

2007 ◽

Vol 64 (8) ◽

pp. 519-523 ◽

Cited By ~ 2

Author(s):

Marina Deljanin-Ilic ◽

Stevan Ilic

Keyword(s):

Myocardial Infarction ◽

Coronary Angiography ◽

Exercise Test ◽

Stress Echocardiography ◽

Wall Motion ◽

Prognostic Significance ◽

Silent Myocardial Ischemia ◽

Wall Motion Score Index ◽

St Segment ◽

Score Index

Background/Aim. Silent myocardial ischemia (MI) can be detected in subjects with any symptoms, in patients after myocardial infarction and in coronary patients who have episodes of symptomatic, as well as of silent MI. This study was carried out to evaluate the frequency, characteristics and prognostic significance of silent MI detected in stress echocardiography test in patients after myocardial infarction. Methods. In 210 patients within three months after myocardial infarction exercise test was performed. In those patients with ischemic ST depression on exercise electrocardiogram, in order to confirm MI stress echocardiography was additionally performed. To assess the incidence of major cariovascular events, all the patients were followed at least five years after the first myocardial infraction. Results. Out of 210 patients 88 (42%) had ischemic response during stress echocardiography test. Out of 88 patients with MI 54 (61%) had anginal pain (patients with symptomatic MI), while 34 (39%) were free of symptoms (patients with silent MI). Level of exercise test, heart rate, time to the onset of ST segment depression, and the magnitude of ST segment depression were similar in both subgroups of the patients with MI. Duration of exercise test was longer in patients with silent MI (p < 0.05). Wall motion score index during stress echocardiography was higher in patients with symptomatic MI (p < 0.05). Coronary angiography findings were similar in patients with silent and those with symptomatic MI. During a five- yearsfollow- up period the occurrence of major cardic events (cardiac mortality and recurrent myocardial infarction) was similar in both subgroups of the patients with MI. Conclusion. In more than one third of patients after myocardial infarction silent MI during stress echocardiography was detected. The patients with silent ischemia had longer duration of exercise test and smaller wall motion score index on stress echocardiography. There was no difference in coronary angiography finding between patients with silent and those with symptomatic MI. The incidence of major cardiac events during a five- years- follow-up was similar in the patients with silent and those with symptomatic MI. .

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