Identification of a Novel HIV-1 Second-Generation Recombinant Form (CRF01_AE/07_BC) in Men Who Have Sex with Men in Beijing, China

2019 ◽  
Vol 35 (5) ◽  
pp. 500-504 ◽  
Author(s):  
Mingqiang Hao ◽  
Juan Wang ◽  
Shufang He ◽  
Yinxiao Hao ◽  
Jingrong Ye ◽  
...  
2017 ◽  
Vol 33 (11) ◽  
pp. 1175-1179 ◽  
Author(s):  
Chen Wang ◽  
Yan Wang ◽  
Desheng Kong ◽  
Ruolei Xin ◽  
Weisi Xu ◽  
...  

2017 ◽  
Vol 33 (10) ◽  
pp. 1070-1076 ◽  
Author(s):  
Xue Li ◽  
Mingqiang Hao ◽  
Yinxiao Hao ◽  
Jingrong Ye ◽  
Ruolei Xin ◽  
...  

2015 ◽  
Vol 31 (3) ◽  
pp. 342-346 ◽  
Author(s):  
Zheng Li ◽  
Huamian Wei ◽  
Yi Feng ◽  
Jia Li ◽  
Marcia L. Kalish ◽  
...  

2019 ◽  
Vol 79 (6) ◽  
pp. 612-625 ◽  
Author(s):  
Xi Li ◽  
Jianjun Wu ◽  
Yu Zhang ◽  
Yuelan Shen ◽  
Hanping Li ◽  
...  

2020 ◽  
Vol 18 ◽  
Author(s):  
Yin Yueqi ◽  
Zhou Ying ◽  
Lu Jing ◽  
Guo Hongxiong ◽  
Chen Jianshuang ◽  
...  

Background: CRF01_AE and CRF07_BC are the two major HIV-1 virus strains circulating in China. The proportion of dominant subtypes (CRF01_AE and CRF07_BC) among MSM in Jiangsu province was over 80%. A large number of URFs have been found in China in recently years. Objective: This study aimed to report on novel HIV-1 recombinants. Method: We constructed Phylogenetic trees using the maximum likelihood (ML) method with 1000 bootstrap replicates in IQ-TREE 1.6.8 software and determined recombination break points using SimPlot 3.5.1. Results: We identified a novel, second-generation HIV-1 recombinant (JS020202) between CRF01_AE and CRF07_BC. The analysis of near full-length genome (NFLG) showed there were at least 8 breakpoints inner virus, which differed from any previously identified CRF and URF around the world. Conclusion: Novel diverse CRF01_AE/07_BC suggested the complexity trends of HIV-1 genetics. The emergency situation of diverse recombinant strains should be monitored continuously.


2015 ◽  
Vol 31 (7) ◽  
pp. 745-748 ◽  
Author(s):  
Jing Yan ◽  
Ruolei Xin ◽  
Zheng Li ◽  
Yi Feng ◽  
Hongyan Lu ◽  
...  

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