Continuous Intravenous Insulin: An Evaluation in Bariatric Patients Outside of the Intensive Care Unit

2012 ◽  
Vol 7 (4) ◽  
pp. 172-182
Author(s):  
Melanie E. Mabrey ◽  
Allison Vorderstrasse ◽  
Mary Champagne ◽  
Lisa Clark Pickett

2005 ◽  
Vol 33 ◽  
pp. A75
Author(s):  
andre bonnici ◽  
Robert Salasidis ◽  
Judith Marin ◽  
Patrick Bouchard ◽  
Marcin Zakrzewski ◽  
...  


2020 ◽  
Vol 26 (1) ◽  
pp. 43-50
Author(s):  
Eli E. Miller ◽  
Mumtu Lalla ◽  
Alyssa Zaidi ◽  
May Elgash ◽  
Huaqing Zhao ◽  
...  

Objective: Consensus guidelines recommend that intensive care unit (ICU) patients with blood glucose (BG) levels >180 mg/dL receive continuous intravenous insulin (CII). The effectiveness of CII at controlling BG levels among patients who are eating relative to those who are eating nothing by mouth (nil per os; NPO) has not been described. Methods: We conducted a retrospective cohort study of 260 adult patients (156 eating, 104 NPO) admitted to an ICU between January 1, 2014, and December 31, 2014, who received CII. Patients were excluded for a diagnosis of diabetic ketoacidosis or hyperglycemic hyperosmolar nonketotic syndrome, admission to an obstetrics service, or receiving continuous enteral or parenteral nutrition. Results: Among 22 baseline characteristics, the proportion of patients receiving glucocorticoid treatment (GCTx) (17.3% eating, 37.5% NPO; P<.001) and APACHE II score (15.0 ± 7.5 eating, 17.9 ± 7.9 NPO; P = .004) were significantly different between eating and NPO patients. There was no significant difference in the primary outcome of patient-day weighted mean BG overall (153 ± 8 mg/dL eating, 156 ± 7 mg/dL NPO; P = .73), or day-by-day BG ( P = .37) adjusted for GCTx and APACHE score. Surprisingly, there was a significant difference in the distribution of BG values, with eating patients having a higher percentage of BG readings in the recommended range of 140 to 180 mg/dL. However, eating patients showed greater glucose variability (coefficient of variation 23.1 ± 1.0 eating, 21.2 ± 1.0 NPO; P = .034). Conclusion: Eating may not adversely affect BG levels of ICU patients receiving CII. Whether or not prandial insulin improves glycemic control in this setting should be studied. Abbreviations: BG = blood glucose; CII = continuous insulin infusion; CV = coefficient of variation; HbA1c = hemoglobin A1c; ICU = intensive care unit; NPO = nil per os; PDWMBG = patient day weighted mean blood glucose





2007 ◽  
Vol 64 (4) ◽  
pp. 385-395 ◽  
Author(s):  
Rhonda S. Rea ◽  
Amy Calabrese Donihi ◽  
MaryBeth Bobeck ◽  
Peter Herout ◽  
Teresa P. McKaveney ◽  
...  


2011 ◽  
Vol 31 (6) ◽  
pp. 27-35 ◽  
Author(s):  
Rabia Khalaila ◽  
Eugene Libersky ◽  
Dina Catz ◽  
Elina Pomerantsev ◽  
Abed Bayya ◽  
...  

BackgroundRecent evidence has linked tight glucose control to worsened clinical outcomes among adults in intensive care units.ObjectiveTo evaluate the effectiveness and safety of a nurse-led intravenous insulin protocol designed to achieve conservative blood glucose control in patients in a medical intensive care unit.MethodsA nurse-led intravenous insulin protocol was developed, targeting blood glucose levels at 110 to 149 mg/dL. Hypoglycemia was defined as a blood glucose level less than 70 mg/dL. Patients admitted to the medical intensive care unit who required an insulin infusion were enrolled in the study. Blood glucose levels in those patients were compared with levels in 153 historical control patients admitted to the unit in the 12 months before the protocol was implemented who required an insulin infusion.ResultsNinety-six patients were enrolled and treated with the protocol. The protocol and control groups had similar characteristics at baseline. More measurements in the protocol group than in the control group (46.3% vs 36.1%, P&lt;.001) were within the target glucose range (110–149 mg/dL). Hyperglycemia (blood glucose ≥200 mg/dL) occurred less often in the protocol group than in the control group (14.8% vs 20.1%, P=.003). Hypoglycemic events (blood glucose &lt;70 mg/dL) also occurred less often in the protocol group (0.07% vs 0.83%, P&lt;.001).ConclusionsImplementation of a nurse-led, conservative intravenous insulin protocol in the medical intensive care unit is effective and safe and markedly reduces the rate of hypoglycemia.



2007 ◽  
Vol 9 (3) ◽  
pp. 232-240 ◽  
Author(s):  
Rattan Juneja ◽  
Corbin Roudebush ◽  
Nilay Kumar ◽  
Angela Macy ◽  
Adam Golas ◽  
...  


2021 ◽  
pp. 175114372110433
Author(s):  
Jessica Moncrieff ◽  
Vijay Jayagopal ◽  
David Yates

Good glycaemic control confers an outcome benefit in both diabetic and non-diabetic critically unwell patients. Critically unwell patients receiving intravenous insulin in the intensive care unit (ICU) require hourly glucose monitoring. This brief communication highlights the impact of the introduction of the FreeStyle Libre glucose monitor, a form of continuous glucose monitoring, on the frequency of glucose recordings in patients receiving intravenous insulin in the ICU at York Teaching Hospital NHS Foundation Trust.



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