Characterization of Pc Promoter Variants of Class 1 Integrons inEscherichia coliIsolates from Poultry Meat

2013 ◽  
Vol 10 (12) ◽  
pp. 1075-1077 ◽  
Author(s):  
Leila Soufi ◽  
Yolanda Sáenz ◽  
Laura Vinué ◽  
Mohamed Salah Abbassi ◽  
Salah Hammami ◽  
...  
Keyword(s):  
Poultry Meat ◽  
Class 1 Integrons ◽  
Class 1

scholarly journals Occurrence and characterization of class 1 integrons in Escherichia coli from healthy individuals and those with urinary infection

2017 ◽  
Vol 66 (5) ◽  
pp. 577-583 ◽  
Author(s):  
Clarisse Oliveira-Pinto ◽  
Cristiane Diamantino ◽  
Patrícia L Oliveira ◽  
Mariana P Reis ◽  
Patrícia S Costa ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Infection ◽  
Healthy Individuals ◽  
Class 1 Integrons ◽  
Class 1

Prevalence and molecular characterization of class 1 integrons among clinical isolates of Pseudomonas aeruginosa in Northwest of Iran

2017 ◽  
Vol 32 (2) ◽  
pp. 109-115 ◽  
Author(s):  
Hamid Reza Goli ◽  
Mohammad Reza Nahaei ◽  
Mohammad Ahangarzadeh Rezaee ◽  
Alka Hasani ◽  
Hossein Samadi Kafil ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Molecular Characterization ◽  
Clinical Isolates ◽  
Class 1 Integrons ◽  
Class 1 ◽  
Northwest Of Iran

scholarly journals Identification and characterization of two novel ISCR1-associated genes dfrA42 and dfrA43 encoding trimethoprim resistant dihydrofolate reductases

2021 ◽  
Author(s):  
Ling Li ◽  
Mengge Zhang ◽  
Wenjia Wang ◽  
Ruirui Xia ◽  
Yanan Ma ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Complex Class ◽  
Class 1 Integrons ◽  
Class 1 ◽  
Dihydrofolate Reductases ◽  
High Level ◽  
Identification And Characterization

Two novel ISCR1-associated dfr genes, dfrA42 and dfrA43, were identified from trimethoprim (TMP)-resistant Proteus strains and were shown to confer high level TMP resistance (MIC ≥ 1024 mg/L) when cloned into Escherichia coli. These genes were hosted by complex class 1 integrons suggesting their potentials for dissemination. Analysis of enzymatic parameters and TMP affinity were performed, suggesting that the mechanism of TMP resistance for these novel DHFRs is the reduction of binding with TMP.

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