Association of Inflammatory Cytokines and Endothelial Adhesion Molecules with Immunological, Virological, and Cardiometabolic Disease in HIV-Infected Individuals

2014 ◽  
Vol 34 (5) ◽  
pp. 385-393 ◽  
Author(s):  
Heloísa Ramos Lacerda ◽  
Maria da Conceição Correia Falcão ◽  
Valéria Maria Gonçalves de Albuquerque ◽  
Josefina Claudia Zírpoli ◽  
Demócrito de Barros Miranda-Filho ◽  
...  
Keyword(s):  
Adhesion Molecules ◽  
Inflammatory Cytokines ◽  
Cardiometabolic Disease ◽  
Endothelial Adhesion Molecules

Changes of Vascular Endothelium Adhesive Properties in Patients with Chronic Generalized Slight Periodontitis During the Treatment

2015 ◽  
Vol 22 (4) ◽  
pp. 79-82
Author(s):  
Жданова ◽  
O. Zhdanova ◽  
Широков ◽  
V. Shirokov ◽  
Говорунова ◽  
...  
Keyword(s):  
Serum Concentration ◽  
Adhesion Molecules ◽  
Inflammatory Cytokines ◽  
Interleukin 1 ◽  
Intercellular Adhesion Molecule ◽  
Immunoglobulin Superfamily ◽  
Control Group ◽  
Adhesive Properties ◽  
Endothelial Adhesion Molecules ◽  
Pro Inflammatory Cytokines

The article presents the description of the changes in the concentrations of pro‐inflammatory cytokines and soluble forms of selectins and immunoglobulin superfamily adhesion molecules in patients with chronic generalized slight periodontitis. Serum concentrations of interleukin‐1‐β, tumor necrosis factor‐ α, soluble forms of P‐ and E‐selectins, intercellular adhesion molecule (ICAM‐1), vascular adhesion molecules (VCAM‐1) and platelet‐endothelial adhesion molecules (PECAM‐1) in healthy subjects and patients with slight periodontitis before and after treatment were assessed. It was found that the serum concentration of sICAM‐1, sVCAM‐1, sP‐, sE‐ selektins and pro‐inflammatory cytokines are increased in patients with chronic generalized periodontitis. The increase of serum concentration of soluble forms of selectins is expressed more significantly than sICAM‐1 and sVCAM‐1. There are no statistically significant changes of serum sPECAM‐1 in the examined group of patients in comparison with control. Complex therapy, including etiological and pathogenetic treatment, is completely normalized the concentration of pro‐inflammatory cytokines, and soluble forms of studied endothelial adhesion molecules in patients with chronic generalized slight periodontitis. All the studied parameters in patients with chronic generalized slight periodontitis after treatment are in the range of the control group variability.

Organotypic Endothelial Adhesion Molecules are Key For  Trypanosoma Brucei Tropism and Virulence

2021 ◽  
Author(s):  
Mariana De Niz ◽  
Daniela Bras ◽  
Mafalda Pedro ◽  
Ana Margarida Nascimento ◽  
Claudio Franco ◽  
...  
Keyword(s):  
Adhesion Molecules ◽  
Trypanosoma Brucei ◽  
Endothelial Adhesion Molecules

scholarly journals Expression of endothelial adhesion molecules and recruitment of neutrophils after traumatic brain injury in rats

1997 ◽  
Vol 61 (3) ◽  
pp. 279-285 ◽  
Author(s):  
T. M. Carlos ◽  
R. S. B. Clark ◽  
D. Franicola-Higgins ◽  
J. K. Schiding ◽  
P. M. Kochanek
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Adhesion Molecules ◽  
Endothelial Adhesion Molecules

VARIATION IN EXPRESSION OF ENDOTHELIAL ADHESION MOLECULES IN PRETRANSPLANT AND TRANSPLANTED KIDNEYS-CORRELATION WITH INTRAGRAFT EVENTS

1993 ◽  
Vol 55 (1) ◽  
pp. 117-123 ◽  
Author(s):  
SUSAN V. FUGGLE ◽  
JEREMY B. SANDERSON ◽  
DEREK W. R. GRAY ◽  
ARTHUR RICHARDSON ◽  
PETER J. MORRIS
Keyword(s):  
Adhesion Molecules ◽  
Endothelial Adhesion Molecules ◽  
Transplanted Kidneys

The Expression of Leukocyte-Endothelial Adhesion Molecules Is Increased in Perennial Allergic Rhinitis

1992 ◽  
Vol 7 (4) ◽  
pp. 393-398 ◽  
Author(s):  
S. Montefort ◽  
I. H. Feather ◽  
S. J. Wilson ◽  
D. O. Haskard ◽  
T. H. Lee ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Adhesion Molecules ◽  
Perennial Allergic Rhinitis ◽  
Endothelial Adhesion Molecules

Various adhesion molecules impair microvascular leukocyte kinetics in ventilator-induced lung injury

2006 ◽  
Vol 290 (6) ◽  
pp. L1059-L1068 ◽  
Author(s):  
Naoki Miyao ◽  
Yukio Suzuki ◽  
Kei Takeshita ◽  
Hiroyasu Kudo ◽  
Makoto Ishii ◽  
...  
Keyword(s):  
Lung Injury ◽  
Fluorescence Microscopy ◽  
Adhesion Molecules ◽  
Mononuclear Cells ◽  
Tissue Injury ◽  
Laser Fluorescence ◽  
Confocal Laser ◽  
Polymorphonuclear Cells ◽  
Ventilator Induced Lung Injury ◽  
Endothelial Adhesion Molecules

Although the endothelial expression of various adhesion molecules substantially differs between pulmonary microvessels, their importance for neutrophil and lymphocyte sequestration in ventilator-induced lung injury (VILI) has not been systematically analyzed. We investigated the kinetics of polymorphonuclear cells (PMN) and mononuclear cells (MN) in the acinar microcirculation of the isolated rat lung with VILI by real-time confocal laser fluorescence microscopy, with or without inhibition of ICAM-1, VCAM-1, or P-selectin by monoclonal antibodies (MAb). Adhesion molecules in each microvessel were estimated by intravital fluorescence microscopy or immunohistochemical staining. In high tidal volume-ventilated lungs, 1) ICAM-1, VCAM-1, and P-selectin were differently upregulated in venules, arterioles, and capillaries; 2) venular PMN rolling was improved by inhibition of ICAM-1, VCAM-1, or P-selectin, whereas arteriolar PMN rolling was improved by ICAM-1 or VCAM-1 inhibition; 3) capillary PMN entrapment was ameliorated only by anti-ICAM-1 MAb; and 4) MN rolling in venules and arterioles and MN entrapment in capillaries were improved by ICAM-1 and VCAM-1 inhibition. In conclusion, the contribution of endothelial adhesion molecules to abnormal leukocyte behavior in VILI-injured microcirculation is microvessel and leukocyte specific. ICAM-1- and VCAM-1-dependent, but P-selectin-independent, arteriolar PMN rolling, which is expected to reflect the initial stage of tissue injury, should be taken as a phenomenon unique to ventilator-associated lung injury.

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