In Vitro Antimicrobial Activity of “Last-Resort” Antibiotics Against Unusual Nonfermenting Gram-Negative Bacilli Clinical Isolates

2012 ◽  
Vol 18 (4) ◽  
pp. 396-401 ◽  
Author(s):  
Herve Jacquier ◽  
Alban Le Monnier ◽  
Etienne Carbonnelle ◽  
Stephane Corvec ◽  
Marina Illiaquer ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Clinical Isolates ◽  
Gram Negative ◽  
In Vitro Antimicrobial Activity

scholarly journals In vitro antimicrobial activity of five essential oils on multi-drug resistant Gram-negative clinical isolates

2016 ◽  
Vol 5 (3) ◽  
pp. 212 ◽  
Author(s):  
Hercules Sakkas ◽  
Panagiota Gousia ◽  
Vangelis Economou ◽  
Vassilios Sakkas ◽  
Stefanos Petsios ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Essential Oils ◽  
Clinical Isolates ◽  
Drug Resistant ◽  
Gram Negative ◽  
In Vitro Antimicrobial Activity

In vitro Antimicrobial Activity of Gatifloxacin Compared with Other Quinolones against Clinical Isolates from Cancer Patients

Chemotherapy ◽  
2004 ◽  
Vol 50 (5) ◽  
pp. 214-220 ◽  
Author(s):  
Kenneth V.I. Rolston ◽  
Irfan Vaziri ◽  
Susan Frisbee-Hume ◽  
Harriet Streeter ◽  
Barbara LeBlanc
Keyword(s):  
Antimicrobial Activity ◽  
Cancer Patients ◽  
Clinical Isolates ◽  
In Vitro Antimicrobial Activity

Chemical Composition And In-Vitro Antimicrobial Activity Of The Essential Oils Of Three Greek Achillea Species

2002 ◽  
Vol 57 (3-4) ◽  
pp. 287-290 ◽  
Author(s):  
Prokopios Magiatis ◽  
Alexios-Leandros Skaltsounis ◽  
Ioanna Chinou ◽  
Serkos A. Haroutounian
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Pathogenic Fungi ◽  
The Other ◽  
Gram Negative ◽  
In Vitro Antimicrobial Activity ◽  
Ms Analysis

The chemical composition of the essential oils of Achillea holosericea, Achillea taygetea, Achillea fraasii was determined by GC/MS analysis. Among the ninety-five assayed constituents, camphor, borneol and 1,8-cineol were found to be the major components. The in-vitro antimicrobial activity of these essential oils was evaluated against six bacteria indicating that the first is totally inactive, while the other two possess moderate to strong activities mainly against the Gram negative strains. The essential oil of A. fraasii was also active against the tested pathogenic fungi

scholarly journals Antimicrobial Activity of Ceftriaxone Compared with Cefotaxime in the Presence of Serum Albumin

1995 ◽  
Vol 6 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Swapan K Nath ◽  
Gary A Foster ◽  
Lionel A Mandell ◽  
Coleman Rotstein
Keyword(s):  
Antimicrobial Activity ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Significant Interaction ◽  
Gram Negative ◽  
In Vitro Antimicrobial Activity ◽  
Bactericidal Activities ◽  
Time Kill

The effect of serum albumin on the antimicrobial activity of ceftriaxone, cefotaxime, and a 1:1 ratio of cefotaxime and its desacetyl metabolite against nonpseudomonal Gram-negative bacilli was determined. Antimicrobial activity of drugs was evaluated by measuring minimum inhibitory (mic) and bactericidal (mbc) concentrations in broth with and without human serum albumin. The analysis of logarithmically transformed meanmics andmbcs showed that there was a highly significant interaction between drug and serum albumin (P<0.0001). The inhibitory and bactericidal activities were greatest for cefotaxime followed by cefotaxime/desacetylcefotaxime and ceftriaxone (P<0.01). Time-kill kinetics demonstrated that ceftriaxone was less bactericidal than cefotaxime in broth with albumin. On the basis of these results it was concluded that the in vitro antimicrobial activity of ceftriaxone compared with that of cefotaxime was significantly diminished in the presence of serum albumin.

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