Pharmacogenomics Variation in Drug Metabolizing Enzymes and Transporters in Relation to Docetaxel Toxicity in Lebanese Breast Cancer Patients: Paving the Way for OMICs in Low and Middle Income Countries

2013 ◽  
Vol 17 (7) ◽  
pp. 353-367 ◽  
Author(s):  
Zainab Awada ◽  
Syed Haider ◽  
Arafat Tfayli ◽  
Ali Bazarbachi ◽  
Nagi S. El-Saghir ◽  
...  
2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Grace Kusi ◽  
Adwoa Bemah Boamah Mensah ◽  
Kofi Boamah Mensah ◽  
Veronica Millicent Dzomeku ◽  
Felix Apiribu ◽  
...  

2020 ◽  
Vol 16 (31) ◽  
pp. 2551-2567 ◽  
Author(s):  
Hagar Elghazawy ◽  
Joaira Bakkach ◽  
Mohamed S Zaghloul ◽  
Atlal Abusanad ◽  
Mariam Mohamed Hussein ◽  
...  

Breast cancer is the most common malignancy among women worldwide. The current COVID-19 pandemic represents an unprecedented challenge leading to care disruption, which is more severe in low- and middle-income countries (LMIC) due to existing economic obstacles. This review presents the global perspective and preparedness plans for breast cancer continuum of care amid the COVID-19 outbreak and discusses challenges faced by LMIC in implementing these strategies. Prioritization and triage of breast cancer patients in a multidisciplinary team setting are of paramount importance. Deescalation of systemic and radiation therapy can be utilized safely in selected clinical scenarios. The presence of a framework and resource-adapted recommendations exploiting available evidence-based data with judicious personalized use of current resources is essential for breast cancer care in LMIC during the COVID-19 pandemic.


2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Arafat Tfayli ◽  
Sally Temraz ◽  
Rachel Abou Mrad ◽  
Ali Shamseddine

Breast cancer is a major health care problem that affects more than one million women yearly. While it is traditionally thought of as a disease of the industrialized world, around 45% of breast cancer cases and 55% of breast cancer deaths occur in low and middle income countries. Managing breast cancer in low income countries poses a different set of challenges including access to screening, stage at presentation, adequacy of management and availability of therapeutic interventions. In this paper, we will review the challenges faced in the management of breast cancer in low and middle income countries.


2018 ◽  
Vol 38 (1) ◽  
pp. 161-173 ◽  
Author(s):  
Yehoda M. Martei ◽  
Lydia E. Pace ◽  
Jane E. Brock ◽  
Lawrence N. Shulman

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