Porous Poly(DL-lactic-co-glycolic acid)/Calcium Phosphate Cement Composite for Reconstruction of Bone Defects

2006 ◽  
Vol 12 (4) ◽  
pp. 789-800 ◽  
Author(s):  
P. Quinten Ruhé ◽  
Elizabeth L. Hedberg-Dirk ◽  
Nestor Torio Padron ◽  
Paul H.M. Spauwen ◽  
John A. Jansen ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Glycolic Acid ◽  
Cement Composite ◽  
Bone Defects ◽  
Reconstruction Of Bone Defects ◽  
Porous Poly

Non-decay type fast-setting calcium phosphate cement: composite with sodium alginate

Biomaterials ◽  
1995 ◽  
Vol 16 (7) ◽  
pp. 527-532 ◽  
Author(s):  
Kunio Ishikawa ◽  
Youji Miyamoto ◽  
Masayuki Kon ◽  
Masaru Nagayama ◽  
Kenzo Asaoka
Keyword(s):  
Calcium Phosphate ◽  
Sodium Alginate ◽  
Calcium Phosphate Cement ◽  
Cement Composite

scholarly journals FABRICATION OF POLY(LACTIC-CO-GLYCOLIC ACID)/CALCIUM PHOSPHATE BONE CEMENT COMPOSITE: SYNTHESIZATION OF CALCIUM PHOSPHATE FROM CRAB SHELLS

2018 ◽  
Vol 80 (4) ◽  
Author(s):  
Mohammad Redzuan Abdul Hanan ◽  
Ahmad Kafrawi Nasution ◽  
Rafaqat Hussain ◽  
Syafiqah Saidin
Keyword(s):  
Calcium Phosphate ◽  
Bone Cement ◽  
Glycolic Acid ◽  
Waste Product ◽  
Cement Composite ◽  
Chemical Route ◽  
Calcium Phosphate Bone Cement ◽  
Calcium Compound ◽  
Dsc Analyses

Crab shells are waste product, rich with calcium compound. Calcium element is often used as a material for bone scaffold due to its bioactive and biodegradation properties. In this study, calcium phosphate (CaP) nanoparticles were synthesized from crab shells through a wet chemical route. The CaP nanoparticles were then sintered and mixed with poly(lactic-co-glycolic acid) (PLGA) to form a bone cement composite. The mixture was casted in a cylinder shape and it was characterized through ATR-FTIR, XRD, FESEM, contact angle and DSC analyses. The CaP pellet and the CaP/PLGA bone cement composite were then subjected to in vitro simulated body fluid (SBF) bioactivity test. The CaP/PLGA bone cement composite was found to have a composition of crystal CaP and PLGA with a tolerable glass transition state, suitable to be used in a physiological environment. The CaP nanoparticles were agglomerated on the 3D interconnected surface of PLGA. The hydrophobicity of the CaP was increased (66.94%) with the addition of PLGA as a binder matrix where this composite has induced the formation of apatite layer. This bioactive property is crucial in fabricating a bone substitute material as it can promotes cell penetration, attachment and proliferation..

Preparation and characterization of calcium phosphate/pectin scaffolds for bone tissue engineering

RSC Advances ◽  
2016 ◽  
Vol 6 (67) ◽  
pp. 62071-62082 ◽  
Author(s):  
Lisheng Zhao ◽  
Junjie Li ◽  
Liang Zhang ◽  
Yu Wang ◽  
Jiexin Wang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Compressive Strength ◽  
Calcium Phosphate ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Clinical Application ◽  
Calcium Phosphate Cement ◽  
Bone Defects

A calcium phosphate cement (CPC) scaffold has been used to repair bone defects, but its low compressive strength and poor osteogenesis greatly hinder its clinical application.

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