Effects of aerobic exercise and dietary carbohydrate on energy expenditure and body composition during weight reduction in obese women

1995 ◽  
Vol 61 (3) ◽  
pp. 486-494 ◽  
Author(s):  
S B Racette ◽  
D A Schoeller ◽  
R F Kushner ◽  
K M Neil ◽  
K Herling-Iaffaldano
1978 ◽  
Vol 31 (5) ◽  
pp. 750-763 ◽  
Author(s):  
I Warnold ◽  
G Carlgren ◽  
M Krotkiewski

2020 ◽  
Vol 105 (4) ◽  
pp. e1741-e1748 ◽  
Author(s):  
Emanuele Muraca ◽  
Stefano Ciardullo ◽  
Alice Oltolini ◽  
Francesca Zerbini ◽  
Eleonora Bianconi ◽  
...  

Abstract Context Growing evidence suggests that appropriate levothyroxine (LT4) replacement therapy may not correct the full set of metabolic defects afflicting individuals with hypothyroidism. Objective To assess whether obese subjects with primary hypothyroidism are characterized by alterations of the resting energy expenditure (REE). Design Retrospective analysis of a set of data about obese women attending the outpatients service of a single obesity center from January 2013 to July 2019. Patients A total of 649 nondiabetic women with body mass index (BMI) > 30 kg/m2 and thyrotropin (TSH) level 0.4–4.0 mU/L were segregated into 2 groups: patients with primary hypothyroidism taking LT4 therapy (n = 85) and patients with normal thyroid function (n = 564). Main outcomes REE and body composition assessed using indirect calorimetry and bioimpedance. Results REE was reduced in women with hypothyroidism in LT4 therapy when compared with controls (28.59 ± 3.26 vs 29.91 ± 3.59 kcal/kg fat-free mass (FFM)/day), including when adjusted for age, BMI, body composition, and level of physical activity (P = 0.008). This metabolic difference was attenuated only when adjustment for homeostatic model assessment of insulin resistance (HOMA-IR) was performed. Conclusions This study demonstrated that obese hypothyroid women in LT4 therapy, with normal serum TSH level compared with euthyroid controls, are characterized by reduced REE, in line with the hypothesis that standard LT4 replacement therapy may not fully correct metabolic alterations related to hypothyroidism. We are not able to exclude that this feature may be influenced by the modulation of insulin sensitivity at the liver site, induced by LT4 oral administration.


2000 ◽  
Vol 24 (12) ◽  
pp. 1567-1572 ◽  
Author(s):  
L Karhunen ◽  
A Franssila-Kallunki ◽  
P Rissanen ◽  
R Valve ◽  
M Kolehmainen ◽  
...  

Metabolism ◽  
1992 ◽  
Vol 41 (7) ◽  
pp. 686-688 ◽  
Author(s):  
Arne Astrup ◽  
Benjamin Buemann ◽  
Niels Juel Christensen ◽  
Søren Toubro ◽  
Grete Thorbek ◽  
...  

Appetite ◽  
2007 ◽  
Vol 49 (3) ◽  
pp. 635-643 ◽  
Author(s):  
Eliane Lopes Rosado ◽  
Josefina Bressan ◽  
Marta F. Martins ◽  
Paulo R. Cecon ◽  
Jose Alfredo Martínez

1995 ◽  
Vol 25 (1) ◽  
pp. 195-198 ◽  
Author(s):  
G. F. Adami ◽  
P. Gandolfo ◽  
A. Campostano ◽  
F. Cocchi ◽  
B. Bauer ◽  
...  

SynopsisThe study was carried out in two groups of massively obese women with BMI values who were to undergo bariatric surgery. The patients were evaluated for weight variability and for the presence and the frequency of binge eating. Body composition, resting energy expenditure (REE) and metabolic parameters were also measured. When non-bingeing individuals were compared with patients who met Binge Eating Disorder criteria, no differences in body composition, fat distribution, REE values and concentrations of serum lipids, insulin and thyroid hormones were found. On the other hand, weight variability due to reduced diet in the subjects' lifetime was significantly higher. This study does not support the hypothesis that in massively obese women binge eating is somehow induced by a reduced energy expenditure.


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