Characterization of Monoclonal Antihuman Small Bowel and Colon Specific Mucin Antibodies

1990 ◽  
Vol 93 (5) ◽  
pp. 621-630
Author(s):  
Thomas P. Prindiville ◽  
Mary Cantrell ◽  
M. E. Gershwin ◽  
Boris H. Ruebner
Keyword(s):  
2008 ◽  
Vol 43 (8) ◽  
pp. 589-596 ◽  
Author(s):  
Mayumi Kodama ◽  
Hirofumi Uto ◽  
Masatsugu Numata ◽  
Takeshi Hori ◽  
Takanobu Murayama ◽  
...  

2018 ◽  
Vol 4 (4) ◽  
Author(s):  
Waqas Ahmad ◽  
Iram Zaheer ◽  
Imran Khalid Niazi ◽  
Khurram Aftab Mufti

Small bowel is not easily accessed by endoscope and diagnosis of its pathology relies on clinical assessment and imaging. Traditional contrast studies have the disadvantage of not including the mural and extramural details. This is best seen with magnetic resonance enterography (MRE) which is rapidly replacing computed tomography enterography due to better soft tissue resolution and lack of ionizing radiation. Comprehensive MRE requires axial and coronal T1- and T2-WI, high-resolution diffusion-weighted images, fat-suppressed three-dimensional T1-W breath-hold gradient-echo images of the abdomen, and pelvis before and after intravenous gadolinium-based contrast material administration. MRE is the preferred imaging technique for small bowel pathology due to its ability to show mural and extramural details which allow differentiation in acute, active, and chronicity of changes. Being radiation free, there is no age limitation for its use.


2018 ◽  
Vol 25 (5) ◽  
pp. 222-229 ◽  
Author(s):  
Joana Ribeiro da Silva ◽  
Rolando Pinho ◽  
Adélia Rodrigues ◽  
Ana Ponte ◽  
Jaime Rodrigues ◽  
...  

2015 ◽  
Vol 185 (2) ◽  
pp. 550-562 ◽  
Author(s):  
Hirobumi Suzuki ◽  
Yoshihiro Hirata ◽  
Nobumi Suzuki ◽  
Sozaburo Ihara ◽  
Kosuke Sakitani ◽  
...  

Endoscopy ◽  
2007 ◽  
Vol 39 (12) ◽  
pp. 1059-1063 ◽  
Author(s):  
M. Bellutti ◽  
K. Mönkemüller ◽  
L. Fry ◽  
F. Dombrowski ◽  
P. Malfertheiner

2021 ◽  
Vol 09 (04) ◽  
pp. E507-E512
Author(s):  
Alvaro Martinez-Alcalá ◽  
Lucía C. Fry ◽  
Thomas Kröner ◽  
Shajan Peter ◽  
Carlo Contreras ◽  
...  

Abstract Background and study aims Information about the endoscopic characterization of small bowel gastrointestinal tumors (GISTs) is limited. The aim of this case study was to describe the endoscopic spectrum of small bowel GISTs and to present a practical classification. Patients and methods Observational, retrospective, consecutive case series of patients with small bowel GIST. Results A total of 10 small bowel GISTs were found in patients (6 male, 4 female, mean age 52 years, range 28 to 68).). All patients presented with obscure gastrointestinal bleeding (overt, n = 8, occult, n = 2). Most GISTs were present in the proximal or middle small bowel (n = 7). The endoscopic tumor characteristics could be categorized as follows: submucosal round (n = 4), submucosal sessile (n = 2), and invasive/penetrating) (n = 4). The mucosa overlying the tumor was normal (n = 4), grooved (n = 3) or frankly ulcerated (n = 3). Tumor size ranged from 8 mm to 50 mm. Biopsy was negative in all patients with normal mucosa but showed tumor in all patients with ulcerations. Regardless of biopsy results, all patients were sent for surgery. Nine resections were carried out. One patient refused surgery. There were no complications of endoscopy in this cohort. Conclusion Our series shows that GISTs have a wider spectrum of endoscopic characteristics than previously described. The round type with normal overlying mucosa was equally prevalent as the grooved or ulcerated variant. Endoscopists should be aware of this wide spectrum of presentation of small bowel GIST.


1998 ◽  
Vol 275 (1) ◽  
pp. G114-G124 ◽  
Author(s):  
Alka Goyal ◽  
Renu Singh ◽  
Elzbieta A. Swietlicki ◽  
Marc S. Levin ◽  
Deborah C. Rubin

The rodent intestinal mucosa undergoes a remarkable morphogenesis as the crypt-villus axis is formed. Endoderm-mesenchymal interactions play a critical role in this process. Epimorphin is a mesenchymal protein postulated to play a role in lung and skin morphogenesis. The rat homologue, syntaxin 2, belongs to a family of integral membrane proteins that function in vesicle docking and fusion. To clarify its role in fetal gut morphogenesis, epimorphin expression was examined during ontogeny, in an isograft model of ischemic injury and mucosal repair, and during intestinal adaptation after small bowel resection. Epimorphin/syntaxin 2 mRNA levels were increased in fetal gut during lumen formation and villus morphogenesis. mRNA levels remained elevated in the first 2 wk after birth and then declined at weaning. In situ hybridization showed epimorphin/syntaxin 2 mRNA in gestational day 14( G14) and G15 intestinal mesenchymal cells and in the mucosal lamina propria during villus formation. Epimorphin/syntaxin 2 mRNA expression increased during villus repair in the isograft. In contrast, in the early stages of intestinal adaptation after small bowel resection, epimorphin/syntaxin 2 mRNA expression was suppressed in the adapting gut. We conclude the cell-specific and temporal patterns of epimorphin expression in the models used in this study suggest a role in the morphogenesis of the crypt-villus axis.


Sign in / Sign up

Export Citation Format

Share Document