Radiographic Characterization of Small Bowel Segments Proximal to the Ileocolonic Anastomosis in Crohnʼs disease (CD): Correlation of Anastomotic Type with Bowel Diameter and Quality of Life

2013 ◽  
Vol 108 ◽  
pp. S536-S537 ◽  
Author(s):  
Hassan Siddiki ◽  
Claudia Ramos Rivers ◽  
Miguel Regueiro ◽  
Michael Dunn ◽  
Andrew Watson ◽  
...  
Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1596
Author(s):  
Marta Diaz-delCastillo ◽  
Rebecca E. Andrews ◽  
Aritri Mandal ◽  
Thomas L. Andersen ◽  
Andrew D. Chantry ◽  
...  

Multiple myeloma (MM) is a bone marrow neoplasia that causes bone pain in 70% patients. While preclinical models of MM have suggested that both nerve sprouting and nerve injury may be causative for the pain, there is a lack of clinical data. Thus, the primary aims of this clinical study are: (1) to provide a deep characterization of the subjective experience of pain and quality of life in MM patients; (2) to investigate disturbances in the bone innervation of MM patients. Secondary aims include exploring correlations between pain and serum inflammatory and bone turnover biomarkers. In a prospective, observational study (clinicaltrials.gov: NCT04273425), patients with suspected MM requiring a diagnostic iliac crest biopsy at Sheffield Teaching Hospital (UK) are invited to participate. Consenting patients answer seven standardized questionnaires assessing pain, quality of life and catastrophizing. Bone turnover biomarkers and inflammatory cytokines are measured in fasting serum samples, and bone innervation is evaluated in diagnostic biopsies. MM patients are invited to a follow-up upon completion of first line treatment. This will be the first deep characterization of pain in MM patients and its correlation with disturbances in bone innervation. Understanding how bone turnover and inflammation correlate to pain in MM is crucial to identify novel analgesic targets for this condition.


2017 ◽  
Vol 101 ◽  
pp. S88
Author(s):  
Lindsay Hogg ◽  
Sarah Pugh ◽  
Girish Gupte ◽  
Jane Hartley ◽  
Rob Jobe ◽  
...  

2011 ◽  
Vol 41 (4) ◽  
pp. 673-683 ◽  
Author(s):  
Tristin Dawne Brisbois ◽  
Ingrid Heila de Kock ◽  
Sharon Mariko Watanabe ◽  
Vickie Elaine Baracos ◽  
Wendy Victoria Wismer

Neurology ◽  
2012 ◽  
Vol 78 (Meeting Abstracts 1) ◽  
pp. S12.005-S12.005
Author(s):  
T. Graves ◽  
Y.-H. Cha ◽  
A. Hahn ◽  
R. Barohn ◽  
A. Amato ◽  
...  

2015 ◽  
Vol 148 (4) ◽  
pp. S-843
Author(s):  
Hillel Vardi ◽  
Michael Friger ◽  
Orly Sarid ◽  
Dan Greenberg ◽  
Doron Schwartz ◽  
...  

Gut ◽  
2016 ◽  
Vol 65 (Suppl 1) ◽  
pp. A106.1-A106
Author(s):  
V Blackwell ◽  
L Holdaway ◽  
S Travis ◽  
S Reddy ◽  
G Vrakas ◽  
...  

2007 ◽  
Vol 9 (1) ◽  
pp. 83-91 ◽  
Author(s):  
Eldrin F. Lewis ◽  
Gervasio A. Lamas ◽  
Eileen O'Meara ◽  
Christopher B. Granger ◽  
Mark E. Dunlap ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document