scholarly journals Migraine and Arterial Stiffness in the Brazilian Longitudinal Study of Adult Health: ELSA-Brasil

2020 ◽  
Vol 33 (5) ◽  
pp. 458-464 ◽  
Author(s):  
Patricia Noemi Apelbaum ◽  
Alessandra Carvalho Goulart ◽  
Itamar de Souza Santos ◽  
Paulo Andrade Lotufo ◽  
Cristina Pellegrino Baena ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Mean Arterial Pressure ◽  
Arterial Stiffness ◽  
Arterial Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Sex Education ◽  
Pulse Wave ◽  
International Headache Society ◽  
Adult Health

Abstract Background The mechanisms that underlie the link between migraine and cardiovascular diseases are not clear and arterial stiffness could play a role in that association. We analyzed the association between migraine and vascular stiffness measured by carotid-to-femoral pulse wave velocity (PWV-cf). Methods In a cross-sectional analysis of a well-defined population from the Longitudinal Study of Adult Health (ELSA-Brasil) with complete and validated information about migraine and aura according to the International Headache Society criteria, the association between arterial stiffness measured by PWV-cf was tested with multiple linear regression models [β (95% CI)] comparing migraine without aura (MO) and migraine with aura (MA) to the reference group no-migraine (NM). Subsequent adjustments were made for mean arterial pressure, age, sex, education level, physical activity, alcohol use, diabetes mellitus, smoking, antihypertensive medication, body mass index, waist circumference, triglycerides, and LDL-c level to test the independence of the association between migraine status and pulse wave velocity. Results We studied 4,649 participants, 2,521 women (25.7% MO and 15% MA) and 2,128 men (11% MO and 4.3% MA). In NM, MO, and MA standard PWV-cf were 8.67 (±1.71) 8.11 (±1.31) and 8.01 (±1.47) m/s, respectively. Unadjusted PWV-cf differed between NM, MA, and MO (P < 0.001). After adjustment for mean arterial pressure PWV-cf in NM did not differ anymore from MA (P = 0.525) and MO (P = 0.121), respectively. Fully adjusted models also yielded nonsignificant coefficients β (95% CI) −0.079 (−0.280; 0.122) and −0.162 (−0.391; 0.067) for MO and MA, respectively. Conclusion In this large cohort of middle-aged adults, aortic PWV was not associated with migraine.

scholarly journals Arterial stiffness as a risk factor for hypotension during induction of general anesthesia

2021 ◽  
Author(s):  
Ianis Siriopol ◽  
Ioana Grigoras ◽  
Dimitrie Siriopol ◽  
Adi Ciumanghel ◽  
Daniel Rusu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Mean Arterial Pressure ◽  
Arterial Stiffness ◽  
Arterial Pressure ◽  
Pulse Wave Velocity ◽  
General Anaesthesia ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Systolic Arterial Pressure ◽  
Post Induction

IntroductionHypotension after induction of general anaesthesia is identified as an independent factor in predicting adverse clinical outcomes. Preoperative evaluation of arterial stiffness could identify patients with an impaired vascular function and an altered haemodynamic response to induction of general anaesthesia. The purpose of this study is to investigate the relationship between arterial stiffness and blood pressure variation during induction of general anaesthesia.Material and methodsThis was an observational study that included patients who underwent surgical procedures under general anaesthesia. We used several systolic arterial pressure and mean arterial pressure thresholds for defining hypotension. Both absolute thresholds and thresholds relative to a baseline blood pressure were chosen based on the most frequently used definitions. Patient carotid-femoral pulse wave velocity determination, preoperative preparation, and induction of general anaesthesia were standardized.ResultsOur study included 115 patients. Both univariate and multivariate analysis showed that carotid-femoral pulse wave velocity was significantly associated with post-induction hypotension when defined as a systolic arterial pressure decrease of > 30% or > 40% from baseline or as a mean arterial pressure decrease of > 40% from baseline. Also, carotid-femoral pulse wave velocity was positively associated with duration of post-induction hypotension.ConclusionsPreoperative assessment of arterial stiffness identifies patients at risk of a pronounced decrease in blood pressure during induction of general anaesthesia.

Two Methods to Assess Aortic Compliance Using Blood Pressure and Pulse-Wave Velocity

2020 ◽  
Author(s):  
Noah Manring ◽  
Mouayed Al-Toki
Keyword(s):  
Blood Pressure ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Rubber Tube ◽  
Aortic Compliance ◽  
Cardiovascular Morbidity And Mortality

Abstract Aortic compliance has been well established as an independent predictor of cardiovascular morbidity and mortality. The current "gold standard" for assessing aortic compliance is to use the carotid-femoral pulse-wave velocity (PWV) as a surrogate; however, PWV alone has been discussed in the literature as being inadequate for assessing compliance, especially for elderly patients and others who have a stiff aorta. In this paper an equation for the aortic compliance is developed using two approaches: 1) lumped-parameter modeling based on blood-pressure data and 2) distributed modeling based on the PWV. In-vitro experiments are conducted using a silicone-rubber tube which simulates the aorta, and an actual aorta harvested from a 1-year old, Holstein heifer. For both the rubber aorta and the Holstein aorta, a comparison is made between the blood-pressure model and the PWV model. In conclusion it is shown that good agreement exists between the two models, suggesting that either model may be used depending upon the available data. Furthermore, due to differences in material properties, it is shown that the compliance of the rubber aorta increases with mean arterial-pressure, while the compliance of the Holstein aorta decreases with mean arterial-pressure. Clinical implications of this research are also discussed.

scholarly journals Serum Uric Acid and Pulse Wave Velocity Among Healthy Adults: Baseline Data From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): Table 1.

2015 ◽  
Vol 28 (8) ◽  
pp. 966-970 ◽  
Author(s):  
Cristina Pellegrino Baena ◽  
Paulo Andrade Lotufo ◽  
José Geraldo Mill ◽  
Roberto de Sa Cunha ◽  
Isabela J Benseñor
Keyword(s):  
Uric Acid ◽  
Longitudinal Study ◽  
Pulse Wave Velocity ◽  
Serum Uric Acid ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Healthy Adults ◽  
Baseline Data ◽  
Adult Health

Arterial stiffness following repeated Valsalva maneuvers and resistance exercise in young men

2007 ◽  
Vol 32 (2) ◽  
pp. 257-264 ◽  
Author(s):  
Kevin S. Heffernan ◽  
Sae Young Jae ◽  
David G. Edwards ◽  
Erin E. Kelly ◽  
Bo Fernhall
Keyword(s):  
Blood Pressure ◽  
Mean Arterial Pressure ◽  
Arterial Stiffness ◽  
Arterial Pressure ◽  
Pulse Wave Velocity ◽  
Resistance Exercise ◽  
Pulse Wave ◽  
Lower Body ◽  
Peripheral Arterial ◽  
Finger Plethysmography

The purpose of this study was to compare arterial stiffness after a bout of resistance exercise (RE) and an experimental condition consisting of repeated Valsalva maneuvers (VMs). Fourteen male participants randomly completed a lower-body, unilateral RE bout and a VM bout designed to alter blood pressure (BP) in a similar pulsatile fashion. Pulse-wave velocity (PWV, measured in metres per second (m·s–1)) was used to measure central and peripheral arterial stiffness and was assessed before and 20 min after each perturbation. Beat-to-beat blood pressure (BP) was assessed during bouts using finger plethysmography. Change in systolic BP, diastolic BP, mean arterial pressure, and pulse pressure were similar during both bouts. Central PWV increased after repeated VMs (7.1 ± 0.3 m/s to 7.8 ± 0.3 m/s), but not after RE (7.2 ± 0.3 m/s to 7.2 ± 0.3 m/s) (interaction, p = 0.032). There was no change in peripheral PWV after VM (8.9 ± 0.3 m/s to 9.3 ± 0.3 m/s) or RE (8.5 ± 0.2 m/s to 8.4 ± 0.2 m/s). Arterial stiffness increased after repeated VM. Even though presented with a similar BP load, arterial stiffness did not increase after acute RE. These findings suggest a role for VM in acutely altering arterial properties.

OS 14-07 PULSE WAVE VELOCITY COMPARED WITH MEAN ARTERIAL PRESSURE AND PULSE PRESSURE PROGNOSTIC IN THE POPULATION OF GAOYOU COUNTY, CHINA

2016 ◽  
Vol 34 (Supplement 1) ◽  
pp. e213-e214
Author(s):  
Yichao Lu ◽  
Haifeng Zhang ◽  
Fang Zhou ◽  
Shan-Shan Li ◽  
Fang-Fei Wei ◽  
...  
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Pressure ◽  
Pulse Wave

Abstract 184: Aortic Pulse Wave Velocity Does Not Correlate with Flow Wave Velocity or Mean Arterial Pressure in Robust, in Vitro Cardiovascular Hemodynamic Simulation

2012 ◽  
Vol 32 (suppl_1) ◽  
Author(s):  
Jeffrey Lillie ◽  
Doran Mix ◽  
Karl Schwarz ◽  
Ankur Chandra ◽  
Steven Day ◽  
...  
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Systolic Hypertension ◽  
Pulse Wave ◽  
Isolated Systolic Hypertension ◽  
Pulsed Wave Doppler ◽  
Ventricular Ejection Time ◽  
The Relationship

Introduction: Arterial compliance is a marker for cardiac burden in atherosclerotic disease, with the pressure Pulse Wave Velocity (PWV) correlated to compliance. Current clinical practice employs pulsed wave Doppler to measure Flow Wave Velocity (FWV) as a surrogate of PWV. We hypothesized that PWV and FWV are not directly related and are affected by left ventricular ejection time (LVET). Furthermore, we proposed that aortic PWV is independent of mean arterial pressure (MAP) in the setting of isolated systolic hypertension. Methods: Using a physiologically accurate electromechanical cardiovascular simulator, two solid state manometer-tipped pressure transducers and two transit time flow sensors were located at the aortic root and at the aortic bifurcation. PWV and FWV were directly measured while individually varying contractility and thus LVET. The experiments were repeated at various systemic vascular resistances (SVR) and vascular compliances. Automated signal processing and data extraction techniques were used to calculate the key parameters. Results: As LVET increased, FWV decreased but PWV increased while MAP remained constant for a fixed SVR and compliance. (Figure 1) This trend held consistent at different SVR’s and compliances. The relationship of PWV and FWV with LVET appeared to be exponential and linear respectively. For a constant MAP, the associated PWV varied by up to 50m/s and FWV by up to 10m/s for a change in LVET of 225ms. Conclusions: In conclusion, our data shows that PWV and FWV appear to be inversely related. Our data also suggest that PWV and FWV are independent of MAP in the setting of isolated systolic hypertension. These findings suggest that FWV measured by pulsed wave Doppler may not be a simple surrogate for true PWV. Future work is needed to elucidate the hemodynamic principals governing the relationship between PWV and FWV.

P6.14 WHICH ESTIMATE OF MEAN ARTERIAL PRESSURE IS TO BE USED FOR ADJUSTMENT FOR PULSE WAVE VELOCITY?

2011 ◽  
Vol 5 (4) ◽  
pp. 175
Author(s):  
T.K. Soender ◽  
L.M. Van Bortel ◽  
J. Lambrechtsen ◽  
J. Hangaard ◽  
J. Moeller ◽  
...  
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave

STRUCTURAL AND FUNCTIONAL VASCULAR CHANGES IN HIGH NORMAL ARTERIAL PRESSURE

2020 ◽  
Vol 23 (1) ◽  
pp. 7-11
Author(s):  
P. Nikolov
Keyword(s):  
Arterial Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Pressure ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Aortic Pressure ◽  
Large Arteries ◽  
Central Aortic Pressure ◽  
Significant Difference

The PURPUSE of the present study is changes in function and structure of large arteries in individuals with High Normal Arterial Pressure (HNAP) to be established. MATERIAL and METHODS: Structural and functional changes in the large arteries were investigated in 80 individuals with HNAP and in 45 with optimal arterial pressure (OAP). In terms of arterial stiffness, pulse wave velocity (PWV), augmentation index (AI), central aortic pressure (CAP), pulse pressure (PP) were followed up in HNAP group. Intima media thickness (IMT), flow-induced vasodilatation (FMD), ankle-brachial index (ABI) were also studied. RESULTS: Significantly increased values of pulse wave velocity, augmentation index, central aortic pressure, pulse pressure are reported in the HNAP group. In terms of IMT and ABI, being in the reference interval, there is no significant difference between HNAP and OAP groups. The calculated cardiovascular risk (CVR) in both groups is low. CONCLUSION: Significantly higher values of pulse wave velocity, augmentation index, central aortic pressure and pulse pressure in the HNAP group are reported.

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