Microbial Growth Patterns in Intravenous Fat Emulsions

1983 ◽  
Vol 40 (10) ◽  
pp. 1650-1653 ◽  
Author(s):  
David Keammerer ◽  
C. Glen Mayhall ◽  
Gaye O. Hall ◽  
Lawrence J. Pesko ◽  
Robert B. Thomas
2013 ◽  
Vol 18 (4) ◽  
pp. 298-302 ◽  
Author(s):  
Bethany M. DeDonato ◽  
Lisa I. Bickford ◽  
Ryan J. Gates

OBJECTIVES To determine whether an extended infusion time (24 hours) of intravenous fat emulsion is associated with an increase in microbial growth, versus a shorter infusion time (12 hours). METHODS Samples were collected from intravenous fat emulsions (n=132), from intravenous fat emulsions prepared in the current 24-hour infusion method (n=55), and from intravenous fat emulsions prepared in the twice-daily (12-hour infusion) method (n=55). In addition, samples were collected from pharmacy (n=22) to test for possible contamination. RESULTS No growth was observed in either arm of the study. CONCLUSIONS Current Kern Medical Center policy of preparation and administration of neonatal intensive care unit intravenous fat emulsion is safe and effective in regard to microbial growth.


2010 ◽  
Vol 44 (4) ◽  
pp. 688-700 ◽  
Author(s):  
Jay M Mirtallo ◽  
Joseph F Dasta ◽  
Kurt C Kleinschmidt ◽  
Joseph Varon

1959 ◽  
Vol 39 (1) ◽  
pp. 145-159 ◽  
Author(s):  
Frederick W. Preston ◽  
George C. Henegar

1984 ◽  
Vol 105 (6) ◽  
pp. 987-990 ◽  
Author(s):  
Dwight A. Powell ◽  
Jeffrey Aungst ◽  
Stephen Snedden ◽  
Nancy Hansen ◽  
Michael Brady

1965 ◽  
Vol 16 (1) ◽  
pp. 129-134 ◽  
Author(s):  
HARRY H. LEVEEN ◽  
PRUDENCE GIORDANO ◽  
ARGIE JOHNSON

1989 ◽  
Vol 72 (3) ◽  
pp. 436-441
Author(s):  
Terry D Cyr ◽  
Robert C Lawrence ◽  
Edward G Lovering

Abstract A photon correlation spectroscopy method has been developed to characterize the size distribution of fat globules in intravenous fat emulsions (IFE) in terms of mean diameter, standard deviation of the distribution, and percentage of large particles outside the distribution. Mean fat globule diameters of samples of all IFE products available in Canada were about 0.3 μm, similar to values reported in the literature. The methodology is sufficiently sensitive to detect the presence of 5% by weight of 2 μm polystyrene microspheres in an intravenous fat emulsion. The effect of changes in instrument settings and variables on the results has been evaluated.


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