scholarly journals Pathological grade-independent prediction of chemosensitivity by CINSARC should rehabilitate adjuvant chemotherapy in soft tissue sarcomas of any grade

2019 ◽  
Vol 30 (2) ◽  
pp. 342-343
Author(s):  
F. Bertucci ◽  
P. Finetti ◽  
A. Monneur ◽  
D. Birnbaum
1986 ◽  
Vol 4 (4) ◽  
pp. 552-558 ◽  
Author(s):  
F Gherlinzoni ◽  
G Bacci ◽  
P Picci ◽  
R Capanna ◽  
P Calderoni ◽  
...  

A new trial for evaluating the effectiveness of adjuvant chemotherapy in high-grade soft-tissue sarcomas of the extremities in adult patients is presented. All patients after local treatment were randomized into two arms, one without further therapy and the other to receive adjuvant chemotherapy (Adriamycin [Farmitalia-Carlo Erba, Milan, Italy], 450 mg/m2). The preliminary results of the study are reported at a median observation period of 27.6 months. Of the 59 patients who entered the study, 79.1% in the chemotherapy group are without sign of disease, whereas the corresponding figure in the nonadjuvant chemotherapy group is 54.3%. The difference between the two groups is statistically significant (P less than .005, log rank test). These preliminary observations encourage continuation of the study.


1981 ◽  
Vol 61 (6) ◽  
pp. 1415-1423 ◽  
Author(s):  
Steven A. Rosenberg ◽  
Joel Tepper ◽  
Eli Glatstein ◽  
Jose Costa ◽  
Robert Young ◽  
...  

2012 ◽  
Vol 21 (2) ◽  
pp. 243-253 ◽  
Author(s):  
Vinod Ravi ◽  
Shreyaskumar Patel

2017 ◽  
Vol 103 (3) ◽  
pp. 213-216 ◽  
Author(s):  
Robert S. Benjamin

Dr. Gianni Bonadonna is internationally recognized as one of the foremost medical oncologists of the 20th century. He is best known for his pioneering work in the development of adjuvant chemotherapy for breast cancer, but he was also the father of sarcoma chemotherapy. The first investigator to study the new chemotherapeutic agent adriamycin in the late 1960s, he noted activity against sarcomas. This article, focusing on adjuvant chemotherapy, adriamycin, and sarcomas, memorializes his achievements and their progeny.


1995 ◽  
Vol 31 ◽  
pp. S179
Author(s):  
S. Frustaci ◽  
H. Zmerly ◽  
A. Buonadonna ◽  
E. Barbieri ◽  
P. Olmi ◽  
...  

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