scholarly journals Commentary on: The Risk of Skin Necrosis Following Hyaluronic Acid Filler Injection in Patients With a History of Cosmetic Rhinoplasty

2018 ◽  
Vol 38 (8) ◽  
pp. 889-891 ◽  
Author(s):  
Claudio DeLorenzi
Keyword(s):  
Hyaluronic Acid ◽  
Skin Necrosis ◽  
Filler Injection ◽  
History Of ◽  
Cosmetic Rhinoplasty

scholarly journals Fillers and Vessels: The Story of Arterial Obstruction after Cosmetic Treatment

2021 ◽  
Vol 6 (2) ◽  
pp. 1-4
Author(s):  
Velthuis PJ
Keyword(s):  
Hyaluronic Acid ◽  
Skin Necrosis ◽  
Ultrasound Guidance ◽  
Arterial Occlusion ◽  
Calcium Hydroxyapatite ◽  
Duplex Sonography ◽  
Low Grade ◽  
Filler Injection ◽  
Retinal Artery ◽  
Cosmetic Medicine

Most popular fillers in cosmetic medicine are hyaluronic acid based. These comprise over 90% of the market and come with the advantage to be soluble in case of complications. Other fillers are contained in the group of bio-stimulatory fillers. They exert a secondary volumizing effect by provoking a low-grade inflammatory response that produces extra collagen. Examples are calcium-hydroxyapatite and L-poly-lactid acid. Finally autologous fat is being used as a filling substance (lipofilling). The gravest complications with fillers are intravascular injections. In particular when injected in arteries fillers can block blood flow and lead to skin necrosis or vison loss in case the material occludes the Central Retinal Artery (CRAO). Two opposing theories about the nature of arterial occlusion exist. One based on Ian Taylor idea of choke anastomoses assume vasoconstriction induced by the filler, both of the primary offended artery and its anastomosing vasosomes. In this case resolving the hyaluronic acid filler with the enzyme hyaluronidase at the primary occluding location would suffice. This is done under ultrasound guidance. The other theory assumes displacement of parts of the filler to end arterioles. Then, the whole affected area has to be flooded with large dosages of hyaluronidase. Obstructions with fillers based on other materials cannot be resolved. It seems logical to prevent intra-arterial filler injection by duplex sonography detection of the course of arteries prior to injection. Ultrasound has additional advantages for cosmetic doctors such as recognizing remains of previously injected filler. It also can give feedback on a physician’s ability to inject filler in the correct subdermal location.

Delayed skin necrosis following hyaluronic acid filler injection: A case report

2020 ◽  
Vol 19 (3) ◽  
pp. 582-584
Author(s):  
Daniel Cassiano ◽  
Tatiana Miyuki Iida ◽  
Ana Lúcia Recio ◽  
Samira Yarak
Keyword(s):  
Hyaluronic Acid ◽  
Case Report ◽  
Skin Necrosis ◽  
Filler Injection

scholarly journals HYALURONIC ACID FILLER INJECTION FOR COSMETIC PURPOSE: SKIN NECROSIS COMPLICATION AND TREATMENT - CASES REPORTS

2021 ◽  
Vol 506 (1-2) ◽  
Author(s):  
Vu Ngoc Lam ◽  
Nguyen Quang Duc ◽  
Le Diep Linh ◽  
Le Thi Thu Hai
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Skin Necrosis ◽  
Early Recognition ◽  
Complete Healing ◽  
Soft Tissue Augmentation ◽  
Filler Materials ◽  
Dermal Fillers ◽  
Filler Injection ◽  
Specific Protocol

Background: Hyaluronic acid (HA) fillers for aesthetic are generally considered safe and the use of dermal fillers for soft tissue augmentation has become a very popular technique in aesthetic practices. Dermal fillers temporarily remove the appearance of rhytids and reduce the depth of skin folds. This is one of the most effective method for facial improvement used in Viet Nam nowadays.  However, complications such as skin necrosis, blind... may happen and hence any filler injection practitioner need to be aware of such side effects, contraindications and precaution to be adopted while using fillers. Even with the most experienced of injectors, adverse effects can and do occur ranging from mild bruising to severe injection necrosis. Aims: HA filler injectors should be able to prevent and treat the severe complication of skin necrosis and detect impending necrosis after injection of a augmentation filler. Materials and Methods: Cases report of 3 patients who were HA filler injection for nose augmentation and had suffered from skin necrosis. These patients were followed for 3-6 months from time of injection of hyaluronic acid filler to complete healing of wound. Results: Complete wound healing were achieved with early recognition and institution of treatment, surgical procedures applied in some severe cases. The functional of the noses are remained but  most of the patients have bad scar on the nose. Discussion: We review cases report of injection necrosis and methods used to prevent and treat this complication. Conclusion: Early recognition of vascular necrosis with specific protocol for treatment after injection necrosis with hyaluronic acid fillers improves the outcome of wound healing.

scholarly journals Hyaluronic Acid Fillers: Where We Have Been and Where We Are Going

2021 ◽  
Author(s):  
Alexander Daoud ◽  
Robert Weiss
Keyword(s):  
Hyaluronic Acid ◽  
Soft Tissue ◽  
The United States ◽  
Soft Tissue Augmentation ◽  
Invasive Treatment ◽  
Filler Injection ◽  
Tissue Augmentation ◽  
History Of ◽  
Vital Component ◽  
Favorable Safety

Since the approval of the United States’ first hyaluronic acid (HA) filler in December 2003, HA fillers have become mainstays of soft tissue augmentation due to their favorable safety profile and minimally invasive treatment nature. The past two decades have not only brought an expansion in the popularity of HA fillers, but also in the number of available HA filler products and indications for cosmetic enhancement. Accordingly, HA filler injection has become one of the most commonly performed cosmetic procedures worldwide. The progression of HA filler products is a study in both biomedical engineering advancements, as well as evolving concepts of beauty and cosmesis. In this chapter, we review the history of these products, including their composition and indications for use. We then explore the prospect of HA fillers for the future of esthetic medicine, as they remain a vital component of nonsurgical soft tissue augmentation.

Ischemic Oculomotor Nerve Palsy and Skin Necrosis Caused by Vascular Embolization After Hyaluronic Acid Filler Injection

2013 ◽  
Vol 71 (4) ◽  
pp. 333-334 ◽  
Author(s):  
Seung Gee Kwon ◽  
Jong Won Hong ◽  
Tai Suk Roh ◽  
Young Seok Kim ◽  
Dong Kyun Rah ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Skin Necrosis ◽  
Nerve Palsy ◽  
Oculomotor Nerve ◽  
Oculomotor Nerve Palsy ◽  
Filler Injection

Efficacy of Percutaneous Intraarterial Facial/Supratrochlear Arterial Hyaluronidase Injection for Treatment of Vascular Embolism Resulting From Hyaluronic Acid Filler Cosmetic Injection

2021 ◽  
Author(s):  
Can Zheng ◽  
Qiang Fu ◽  
Gui-wen Zhou ◽  
Lin-ying Lai ◽  
Li-xia Zhang ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Visual Impairment ◽  
Skin Necrosis ◽  
Clinical Evidence ◽  
Symptomatic Treatment ◽  
Nutritional Therapy ◽  
Facial Artery ◽  
Facial Skin ◽  
Filler Injection ◽  
Rescue Treatment

Abstract Background Vascular embolism is a serious complication of hyaluronic acid (HA) filler cosmetic injection and hyaluronidase injection has been proposed as the treatment. Until now there is a lack of adequate clinical evidence regarding the benefits of treatment for HA filler-induced vascular embolism by percutaneous facial or supratrochlear arterial hyaluronidase injection. Objectives To evaluate the efficacy of percutaneous facial or supratrochlear arterial hyaluronidase injection as a rescue treatment for HA filler-induced vascular embolism. Methods We included 17 patients with vascular embolism after facial HA filler injection. Intraarterial injection of 1500 units hyaluronidase was performed via facial artery for thirteen cases with skin necrosis and via supratrochlear arterial for four cases with severe ptosis and skin necrosis but no visual impairment. Simultaneously, the general symptomatic treatment and nutritional therapy were performed. Results After hyaluronidase injection, the facial skin necrosis in all cases was restored and the ptosis in the four cases was also significantly relieved. Patients were subsequently followed for 1 month to 1 year. The skin necrosis in 16 patients were completely healed and only 1 patient had small, superficial scars. Conclusions It is effective to alleviate the skin necrosis and ptosis resulting from HA filler embolism via percutaneous facial or supratrochlear arterial hyaluronidase injection.

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