Different Extracting Methods of Medicinal Herbs

Salvia officinalis L. is well known as an aromatic and medicinal plant in Albania. Several studies suggest that Salvia officinalis L., in addition to treating minor common illnesses, might potentially provide novel natural treatments for the relief or cure of many serious and life-threatening diseases such as depression, dementia, obesity, diabetes, lupus, heart disease, cancer or antibacterial treatments. The most common methods used for obtaining extracts of essential oils are water distillation, distillation with organic solvents such as hexane, ethanol, methanol and extraction with liquid CO2 under pressure as well. The extracts fractions obtained by these methods are of interest especially in the fields of pharmacology, cosmetic, medicine, food chemistry etc. In this study the extraction of essential oil from Salvia officinalis L is carried out by using an organic solvent (hexane) and liquid CO2 solvent under pressure at 40 0 C. The essential oil extracts are analyzed by thin layer chromatography. The amount of essential oil and the overall yield obtained by hexane distillation method is lower than that obtained by CO2 extraction method. These findings demonstrated that the amount of S. Officinalis oils obtained by CO2 extraction method is optimal, making that suitable for a possible use in pharmaceutical purposes.

Fillers and Vessels: The Story of Arterial Obstruction after Cosmetic Treatment

Most popular fillers in cosmetic medicine are hyaluronic acid based. These comprise over 90% of the market and come with the advantage to be soluble in case of complications. Other fillers are contained in the group of bio-stimulatory fillers. They exert a secondary volumizing effect by provoking a low-grade inflammatory response that produces extra collagen. Examples are calcium-hydroxyapatite and L-poly-lactid acid. Finally autologous fat is being used as a filling substance (lipofilling). The gravest complications with fillers are intravascular injections. In particular when injected in arteries fillers can block blood flow and lead to skin necrosis or vison loss in case the material occludes the Central Retinal Artery (CRAO). Two opposing theories about the nature of arterial occlusion exist. One based on Ian Taylor idea of choke anastomoses assume vasoconstriction induced by the filler, both of the primary offended artery and its anastomosing vasosomes. In this case resolving the hyaluronic acid filler with the enzyme hyaluronidase at the primary occluding location would suffice. This is done under ultrasound guidance. The other theory assumes displacement of parts of the filler to end arterioles. Then, the whole affected area has to be flooded with large dosages of hyaluronidase. Obstructions with fillers based on other materials cannot be resolved. It seems logical to prevent intra-arterial filler injection by duplex sonography detection of the course of arteries prior to injection. Ultrasound has additional advantages for cosmetic doctors such as recognizing remains of previously injected filler. It also can give feedback on a physician’s ability to inject filler in the correct subdermal location.

Regenerative and stem cell-based techniques for facial rejuvenation

This review discusses the most novel ideas and modalities being incorporated into facial rejuvenation. Recent innovative techniques include the use of regenerative stem cell techniques and regeneration supportive modalities such as nano-technology or gene therapies. This review aims to investigate approaches that are less well known and lacking established evidence in order to proactively study these techniques prior to them becoming popularized. These applications and relevant research were reviewed in the context of both surgical and non-surgical modalities in clinical practice. Future directions include the concept of “precision cosmetic medicine” utilizing gene editing and cellular therapies to tailor rejuvenation techniques based on each individual’s genetic make-up and therefore needs.

Post-inflammatory hyperpigmentation of the skin

Post-inflammatory hyperpigmentation is the most benign cause of brownish discolorations of the skin. For this reason it has been little researched. In times of increasing treatments in the field of cosmetic medicine and simultaneous increased attention to the issue of skin cancer, a lack of knowledge may lead to over-treatment of post-inflammatory skin lesions.

Optimum condition investigation on precipitating of calcium carbonate from natural limestone from Bayan soum

Calcium carbonate (CaCO3) is the most widely used filler material in paper, paint, plastic, food, ceramic, cosmetic, medicine and other industries. In the present paper, precipitated calcium carbonate (PCC) has been produced from natural limestone powder (NLP) by the Calcination-Dissolution-Precipitation (CDP) method. Calcination, dissolution and precipitation experiments were carried out under various conditions including: calcination temperature (800, 850, 900, 950, 1000 and 1050 °C), dissolution time (5, 10, 15, 20 and 25 min) and precipitation time (10, 20, 30, 40, 50 and 60 sec). The analyses by XRF showed that the natural limestone contains 80.97% CaCO3 (47.39% CaO), produced PCC sample contains 94.47% CaCO3 (55.81% CaO). It can be seen that the produced PCC sample more purified than natural limestone. Баянгийн ордны шохойн чулуунаас кальцийн карбонат тунадасжуулах тохиромжтой нөхцөлийн судалгаа Кальцийн карбонатыг цаас, будаг, хуванцар, хүнс, керамик, косметик, эмийн болон бусад үйлдвэрлэлд маш өргөн ашигладаг. Бид энэхүү судалгаагаар байгалийн шохойн чулуунаас тунадасжуулсан кальцийн карбонатийг гарган авахдаа Calcination-Dissolution-Precipitation (CDP) буюу шатаан-уусгаж-тунадасжуулах аргыг ашигласан. Байгалийн шохойн чулууг шатаах туршилтыг 800, 850, 900, 950, 1000 болон 1050°C хэмд, уусгалтын хугацаа 5, 10, 15, 20 болон 25 минут, тунадасжуулах хугацааг 10, 20, 30, 40, 50 болон 60 секунд гэсэн хувилбаруудтай явуулсан. Рентген флюресценцийн шинжилгээгээр байгалийн шохойн чулууны дээжинд 80.97% CaCO3, тунадасжуулсан шохойн чулууны дээжинд 94.47% CaCO3 агуулагдаж байгаа нь тогтоогдсоноос үзвэл шатаан-уусгаж-тунадасжуулах аргаар илүү цэвэршилттэй кальцийн карбонат гарган авах боломжтойг харуулж байна. Түлхүүр үг: Шатаах, уусгах, тунадасжуулах, CaCO3, Ca(OH)2

Efficacy of Botulinum Toxin Stereotype A and Its Relevant Mechanisms of Action in Both Cosmetic and Therapeutic Uses

Onabotulinumtoxin A (Botox®) is a parasympathetic autonomic blocking agent which acts as an inhibitor of the neuromuscular transmitter acetylcholine release and as a neuromuscular blocking agent, thereby inducing relaxation of selected muscle fibers for a duration of up to approximately 3 months duration. First approved by the FDA in 1989 and approved for further applications since 1991, the drug has now gained wide acceptance in cosmetic and other therapeutic applications, where the autonomic neurotransmitter acetylcholine blockade can bring about favorable cosmetic responses, particularly in the field of dermatology and cosmetic medicine. Since the original application of Onabotulinumtoxin A was approved for clinical use as a cosmetic agent, numerous additional applications have been approved by the FDA, all of which involve acetylcholine-mediated neuromuscular actions.

Antibacterial and antioxidant activities of ethanol extract of sukun (Artocarpus altilis.) leaves against Pseudomonas aeruginosa

Antioxidants are thought to help the body fight Reactive Oxygen Species (ROS). Antioxidants are defined as “any substance that significantly slows or inhibits oxidation when present in trace amounts relative to an oxidizable substrate.” Antimicrobials generated from plants have been used to treat infectious diseases for millennia. Many investigations have been done on the antibacterial effects of herbal plant extracts., including roots, stems, leaves, and flowers. Artocarpus altilis is a versatile tree plant that is a rich source of calcium, phosphorus, carbohydrates, minerals, and vitamins. Various parts of breadfruit are used as food, cosmetic medicine, clothing, treating diarrhea, high blood pressure, and asthma. This study obtained about determine biological activities of Artocarpus altilis Leaves. The extract was prepared using water with the soxhletation method. The antibacterial activity was determined with minimun inhibitor concentration method with concentration 300-25 mg/mL can inhibit the growth of Pseudomonas aeruginosa, The MIC is the lowest concentration that may stop bacterial growth, and the number of bacteria is 10 colonies. 60.13 0.54 ppm antioxidant activity, fenol (224.67 mg GAE/g) and flavonoids (27.63 mg QE/g). The results show that Artocarpus altilis leaf ethanol extract is antibacterial and antioxidant.

Linear Model Predictive Control for Physical Attractiveness and Risk: Application of Cosmetic Medicine Service

In the online world, the “eyeball economy” has become mainstream. Whether regarding Internet cosmetic medicine endorsers or physical service providers, the topic of physical attractiveness has long been discussed in the field of medical beauty e-commerce. When receiving cosmetic medical services, consumers have frequent contact with employees. Physical attractiveness is the most apparent and easily observed employee characteristic, and consumers base their judgement and behavior on it. In this study, the relationship between the physical attractiveness of cosmetic service employees and consumers’ perceived risk is discussed and clarified. After 366 questionnaires were collected and analyzed, the results indicated that the physical attractiveness of cosmetic service employees was negatively associated with perceived financial, performance, physical, psychological, and social risk. The study offers suggestions for employers. They should recruit more attractive employees. This will increase consumer intention to purchase a service because the consumers’ perceived risks are reduced. It may also enhance repurchase intention and consumption frequency.