scholarly journals Comparing disease screening tests when true disease status is ascertained only for screen positives

Biostatistics ◽  
2001 ◽  
Vol 2 (3) ◽  
pp. 249-260 ◽  
Author(s):  
M. S. Pepe
Keyword(s):  
Disease Status ◽  
Disease Screening ◽  
Screening Tests

scholarly journals Study designs for determining and comparing sensitivities of disease screening tests

2015 ◽  
Vol 22 (4) ◽  
pp. 213-220 ◽  
Author(s):  
Philip C. Prorok ◽  
Barnett S. Kramer ◽  
Anthony B. Miller
Keyword(s):  
Disease Screening ◽  
Screening Tests ◽  
Study Designs

[P1-499]: COMPARISON OF ALZHEIMER's DISEASE SCREENING TESTS IN PRIMARY CARE

2017 ◽  
Vol 13 (7S_Part_9) ◽  
pp. P482-P482
Author(s):  
Nicole R. Fowler ◽  
Anthony J. Perkins ◽  
Sujuan Gao ◽  
Soo Borson ◽  
Malaz A. Boustani
Keyword(s):  
Alzheimer’S Disease ◽  
Primary Care ◽  
Alzheimer's Disease ◽  
Disease Screening ◽  
Screening Tests

Early Development of Drug-Induced Hepatic Necrosis

1971 ◽  
Vol 29 ◽  
pp. 576-577
Author(s):  
F. G. Zaki ◽  
E. Detzi ◽  
C. H. Keysser
Keyword(s):  
Early Development ◽  
Hepatic Necrosis ◽  
Screening Tests ◽  
Dense Matrix ◽  
Sprague Dawley ◽  
Electron Microscopic ◽  
Drug Induced ◽  
Hepatocellular Damage ◽  
Sprague Dawley Rats ◽  
Microscopic Studies

This study represents the first in a series of investigations carried out to elucidate the mechanism(s) of early hepatocellular damage induced by drugs and other related compounds. During screening tests of CNS-active compounds in rats, it has been found that daily oral administration of one of these compounds at a dose level of 40 mg. per kg. of body weight induced diffuse massive hepatic necrosis within 7 weeks in Charles River Sprague Dawley rats of both sexes. Partial hepatectomy enhanced the development of this peculiar type of necrosis (3 weeks instead of 7) while treatment with phenobarbital prior to the administration of the drug delayed the appearance of necrosis but did not reduce its severity.Electron microscopic studies revealed that early development of this liver injury (2 days after the administration of the drug) appeared in the form of small dark osmiophilic vesicles located around the bile canaliculi of all hepatocytes (Fig. 1). These structures differed from the regular microbodies or the pericanalicular multivesicular bodies. They first appeared regularly rounded with electron dense matrix bound with a single membrane. After one week on the drug, these vesicles appeared vacuolated and resembled autophagosomes which soon developed whorls of concentric lamellae or cisterns characteristic of lysosomes (Fig. 2). These lysosomes were found, later on, scattered all over the hepatocytes.

A Validation Study of the Elementary and Advanced Screening Tests of the Clinical Evaluation of Language Functions (CELF)

1983 ◽  
Vol 14 (4) ◽  
pp. 215-222 ◽  
Author(s):  
Sol Ribner ◽  
Laurence Becker ◽  
Sid Marks ◽  
Paul Kahn ◽  
Fred Wolfson
Keyword(s):  
Clinical Evaluation ◽  
Validation Study ◽  
Screening Tests ◽  
Language Functions

HHS Calls for Newborn Heart Disease Screening

2011 ◽  
Vol 45 (11) ◽  
pp. 25
Author(s):  
PATRICE WENDLING
Keyword(s):  
Heart Disease ◽  
Disease Screening
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