[P1-499]: COMPARISON OF ALZHEIMER's DISEASE SCREENING TESTS IN PRIMARY CARE

2017 ◽  
Vol 13 (7S_Part_9) ◽  
pp. P482-P482
Author(s):  
Nicole R. Fowler ◽  
Anthony J. Perkins ◽  
Sujuan Gao ◽  
Soo Borson ◽  
Malaz A. Boustani
Keyword(s):  
Alzheimer’S Disease ◽  
Primary Care ◽  
Alzheimer's Disease ◽  
Disease Screening ◽  
Screening Tests

scholarly journals Promoting Conversations About Cognitive Decline Between Older Adults and Primary Care Providers

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 157-158
Author(s):  
Benjamin Olivari ◽  
Christopher Taylor ◽  
Nia Reed ◽  
Lisa McGuire
Keyword(s):  
Alzheimer’S Disease ◽  
Primary Care ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Cognitive Decline ◽  
Chronic Conditions ◽  
Memory Loss ◽  
Primary Care Providers ◽  
Subjective Cognitive Decline ◽  
Care Providers

Abstract Alzheimer’s disease and related dementias often begin with symptoms of mild memory loss, eventually leading to more severe cognitive impairment, functional impairment, and ultimately, death. Data from the Behavioral Risk Factor Surveillance System core questions related to chronic diseases and from the cognitive decline optional module on subjective cognitive decline (SCD) from the years 2015-2018 were aggregated across the participating 50 states, D.C., and Puerto Rico for this analysis. Among U.S. adults aged 65 years and older, only 39.8% (95%CI=37.6-42.1) of those experiencing SCD reported discussing their SCD symptoms with a healthcare provider. The prevalence of discussing SCD symptoms with a provider was higher among those with at least one chronic condition than among those with no chronic conditions. 30.7% (28.6-32.8) of those aged 65 years and older reported that their SCD led to functional limitations and 28.8% (26.5-31.2) needed assistance with day-to-day activities. For patients aged 65 years and older, Welcome to Medicare visits and Medicare Annual Wellness Visits are critically underutilized primary care access points. Primary care providers can manage chronic conditions, cognitive health, and initiate referrals for testing. Efforts to promote the use of toolkits and diagnostic codes that are available to primary care providers to initiate conversations about memory loss with patients may be utilized to improve detection, diagnosis, and planning for memory problems. Discussions may lead to earlier detection and diagnosis of cognitive impairment, such as Alzheimer’s disease, or other treatable conditions such as delirium or pressure in the brain and avoid costly hospitalizations.

Mild cognitive impairment in primary care: a clinical review

2018 ◽  
Vol 94 (1117) ◽  
pp. 647-652 ◽  
Author(s):  
Georges Assaf ◽  
Maria Tanielian
Keyword(s):  
Alzheimer’S Disease ◽  
Primary Care ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Clinical Review ◽  
Primary Care Physicians ◽  
Early Recognition ◽  
Neuropsychiatric Symptoms ◽  
Evidenced Based

Dementia is projected to become a global health priority but often not diagnosed in its earlier preclinical stage which is mild cognitive impairment (MCI). MCI is generally referred as a transition state between normal cognition and Alzheimer’s disease. Primary care physicians play an important role in its early diagnosis and identification of patients most likely to progress to Alzheimer’s disease while offering evidenced-based interventions that may reverse or halt the progression to further cognitive impairment. The aim of this review is to introduce the concept of MCI in primary care through a case-based clinical review. We discuss the case of a patient with MCI and provide an evidence-based framework for assessment, early recognition and management of MCI while addressing associated risk factors, neuropsychiatric symptoms and prognosis.

Fasu-Net: Fast Alzheimer’s Disease Screening with Undersampled MRI Using Convolutional Neural Networks

2021 ◽  
Vol 11 (8) ◽  
pp. 2211-2221
Author(s):  
Yuanbo Xie ◽  
Haitao Jiang ◽  
Hongwei Du ◽  
Jinzhang Xu ◽  
Bensheng Qiu
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Structural Mri ◽  
Potential Method ◽  
Disease Screening ◽  
Acquisition Time ◽  
Mr Images ◽  
Brain Mr Images ◽  
Magnetic Resonance Imaging Mri ◽  
Questionnaire Method

Alzheimer’s Disease (AD) is a progressive and irreversible neurodegenerative condition, which results in dementia. Mild Cognitive Impairment (MCI) is an intermediate state between normal aging and AD. Instead of traditional questionnaire method, magnetic resonance imaging (MRI) can be used by radiologists to diagnose and screening AD recently, but long acquisition time is not conducive to screening AD and MCI. To solve this problem, we develop a Fasu-Net (Fast Alzheimer’s disease Screening neural network with Undersampled MRI) for AD and MCI clinical classification. The network uses undersampled structural MRI with a shorter acquisition time to improve the screening and diagnosis efficiency of AD. For achieving the best classification result, three axial planes of brain MR images were feed into the Fasu-Net with transfer learning method. The experiment results on undersampled 3D T1-weighted images database (ADNI) show that in the AD versus MCI versus HC (Healthy Controls) classification, the Fasu-Net achieved the accuracy of 91.41%, thus can be a potential method for fast clinical screening of AD.

scholarly journals Screening for Alzheimer's disease in low-educated or illiterate older adults in Brazil: a systematic review

2019 ◽  
Vol 77 (4) ◽  
pp. 279-288 ◽  
Author(s):  
Luciane de Fátima Viola Ortega ◽  
Ivan Aprahamian ◽  
Marcus Kiiti Borges ◽  
João de Castilho Cação ◽  
Mônica Sanches Yassuda
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Diagnostic Accuracy ◽  
Screening Tools ◽  
Screening Tests ◽  
Screening Instruments ◽  
Cognitive Screening ◽  
Inclusion Criteria ◽  
Low Education ◽  
Low Educated

ABSTRACT Cognitive screening instruments are influenced by education and/or culture. In Brazil, as illiteracy and low education rates are high, it is necessary to identify the screening tools with the highest diagnostic accuracy for Alzheimer's disease (AD). Objective: To identify the cognitive screening instruments applied in the Brazilian population with greater accuracy, to detect AD in individuals with a low educational level or who are illiterate. Methods: Systematic search in SciELO, PubMed and LILACS databases of studies that used cognitive screening tests to detect AD in older Brazilian adults with low or no education. Results: We found 328 articles and nine met the inclusion criteria. The identified instruments showed adequate or high diagnostic accuracy. Conclusion: For valid cognitive screening it is important to consider sociocultural and educational factors in the interpretation of results. The construction of specific instruments for the low educated or illiterate elderly should better reflect the difficulties of the Brazilian elderly in different regions of the country.

P2-529: THE ALZHEIMER'S DISEASE AND RELATED DISORDERS (ADRD) PRIMARY CARE ENGAGEMENT CAMPAIGN: PHASE II

2006 ◽  
Vol 14 (7S_Part_17) ◽  
pp. P938-P938
Author(s):  
Lisa O'Neill ◽  
Hartford Morgan ◽  
Raed Sukerji ◽  
Carlos Tafich-Rios ◽  
Steven Rapcsak ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Primary Care ◽  
Alzheimer's Disease ◽  
Phase Ii

scholarly journals Clinical and demographic characteristics of elderly patients with dementia assisted at an outpatient clinic in Southern Brazil

2010 ◽  
Vol 4 (1) ◽  
pp. 42-46 ◽  
Author(s):  
Cláudia Godinho ◽  
Iulek Gorczevski ◽  
Andréa Heisler ◽  
Maria Otília Cerveira ◽  
Márcia Lorena Chaves
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Functional Status ◽  
Outpatient Clinic ◽  
Daily Living ◽  
Cognitive Testing ◽  
Screening Tests ◽  
Behavioral Symptoms ◽  
Significant Difference ◽  
Severity Of Dementia

Abstract The aging of the population is a worldwide phenomenon, where 60% of elders live in developing areas of the world such as Brazil, regions in which few studies have been carried out. Objectives: The goal of this study was to evaluate the clinical and demographic profile of patients with dementing disorders seen at a specialized outpatient clinic in South Brazil. Methods: A sample of 105 demented patients seen at the Dementia Outpatient Clinic from Hospital de Clínicas de Porto Alegre (HCPA), Brazil between June 2004 and June 2008. Evaluation of patients consisted of medical history, cognitive testing, assessment of functional status (Activities of Daily Living Scale - ADL; Instrumental Activities Daily Living - IADL) and application of the Neuropsychiatry Inventory (NPI) for behavioral symptoms. Severity of dementia was evaluated based on the CDR scale. All patients underwent laboratory screening tests and brain imaging exams to define etiology of dementia. Results: Of the whole sample, 71% were female. Age was 79±8 years (mean±SD). Educational level was 4±3 years (mean±SD). Sixty-four patients (60%) presented the diagnosis of Alzheimer's disease. Of the whole sample, 26.7% were classified as CDR=1, 44% as CDR=2 and 29. 3% as CDR=3. A significant difference on the Mini Mental State Examination (MMSE) and functional status scores was observed among the CDR categories (severity). No significant association was found between severity and impairment on memory tests and behavioral symptoms. Conclusions: Alzheimer's disease was the most common etiology, followed by vascular dementia. At diagnosis, most patients presented mild to moderate severity of dementia, independent of cause.

scholarly journals Redefining the Care Continuum to Create a Pipeline to Dementia Care for Minority Populations

2020 ◽  
Vol 11 ◽  
pp. 215013272092168
Author(s):  
Tina R. Sadarangani ◽  
Vanessa Salcedo ◽  
Joshua Chodosh ◽  
Simona Kwon ◽  
Chau Trinh-Shevrin ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Primary Care ◽  
Alzheimer's Disease ◽  
Asian American ◽  
Minority Groups ◽  
Primary Care Providers ◽  
Dementia Care ◽  
Care Providers ◽  
Community Based ◽  
Community Based Organizations

Multiple studies show that racial and ethnic minorities with low socioeconomic status are diagnosed with Alzheimer’s disease and Alzheimer’s disease–related dementias (AD/ADRD) in more advanced disease stages, receive fewer formal services, and have worse health outcomes. For primary care providers confronting this challenge, community-based organizations can be key partners in supporting earlier identification of AD/ADRD and earlier entry into treatment, especially for minority groups. The New York University Center for the Study of Asian American Health, set out to culturally adapt and translate The Kickstart-Assess-Evaluate-Refer (KAER) framework created by the Gerontological Society of America to support earlier detection of dementia in Asian American communities and assist in this community-clinical coordinated care. We found that CBOs play a vital role in dementia care, and are often the first point of contact for concerns around cognitive impairment in ethnically diverse communities. A major strength of these centers is that they provide culturally appropriate group education that focuses on whole group quality of life, rather than singling out any individual. They also offer holistic family-centered care and staff have a deep understanding of cultural and social issues that affect care, including family dynamics. For primary care providers confronting the challenge of delivering evidence-based dementia care in the context of the busy primary care settings, community-based organizations can be key partners in supporting earlier identification of AD/ADRD and earlier entry into treatment, especially for minority groups.

Concluding Comments

1997 ◽  
Vol 9 (S1) ◽  
pp. 328-328
Author(s):  
Alistair Burns
Keyword(s):  
Alzheimer’S Disease ◽  
Primary Care ◽  
Alzheimer's Disease ◽  
Current Knowledge ◽  
Regional Level

Burns: This meeting had a number of aims, one being to review and assimilate current knowledge about Alzheimer's disease (AD), with particular reference to primary care. The introduction of guidelines for GPs would perhaps be much better implemented at a national or even regional level.

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