scholarly journals Chronic Cough and Severe Weight Loss in a 55-Year-Old Previously Healthy Man

2017 ◽  
Vol 65 (2) ◽  
pp. 348-348
2017 ◽  
Vol 65 (2) ◽  
pp. 349-351 ◽  
Author(s):  
Helmut J F Salzer ◽  
Jan Heyckendorf ◽  
Barbara Kalsdorf ◽  
Christian Herzmann ◽  
Christian Hoffmann ◽  
...  

2018 ◽  
Vol 9 (6) ◽  
pp. 1079-1092 ◽  
Author(s):  
Lena Pinzur ◽  
Levent Akyuez ◽  
Lilia Levdansky ◽  
Michal Blumenfeld ◽  
Evgenia Volinsky ◽  
...  

2020 ◽  
Vol 11 (2) ◽  
pp. 38
Author(s):  
M. Chandradasa ◽  
C. S. Kuruppuarachchi ◽  
L. C. Rathnayake ◽  
K. A. L. A. Kuruppuarachchi

2020 ◽  
pp. 1-8
Author(s):  
Júlia Lima ◽  
Paula Portal Teixeira ◽  
Igor da Conceição Eckert ◽  
Camila Ferri Burgel ◽  
Flávia Moraes Silva

Abstract Nutritional status (NS) monitoring is an essential step of the nutrition care process. To assess changes in NS throughout hospitalisation and its ability to predict clinical outcomes, a prospective cohort study with patients over 18 years of age was conducted. The Subjective Global Assessment (SGA) was performed within 48 h of admission and 7 d later. For each patient, decline in NS was assessed by two different methods: changes in SGA category and severe weight loss alone (≥2 % during the first week of hospitalisation). Patients were followed up until discharge to assess length of hospital stay (LOS) and in-hospital mortality and contacted 6 months post-discharge to assess hospital readmission and death. Out of the 601 patients assessed at admission, 299 remained hospitalised for at least 7 d; of those, 16·1 % had a decline in SGA category and 22·8 % had severe weight loss alone. In multivariable analysis, decline in SGA category was associated with 2-fold (95 % CI 1·06, 4·21) increased odds of prolonged LOS and 3·6 (95 % CI 1·05, 12·26) increased odds of hospital readmission at 6 months. Severe weight loss alone was associated with 2·5-increased odds (95 % CI 1·40, 4·64) of prolonged LOS. In conclusion, deterioration of NS was more often identified by severe weight loss than by decline in SGA category. While both methods were associated with prolonged LOS, only changes in the SGA predicted hospital readmission. These findings reinforce the importance of nutritional monitoring and provide guidance for further research to prevent short-term NS deterioration from being left undetected.


2019 ◽  
Vol 90 (6) ◽  
pp. 666-673 ◽  
Author(s):  
Cristina Moglia ◽  
Andrea Calvo ◽  
Maurizio Grassano ◽  
Antonio Canosa ◽  
Umberto Manera ◽  
...  

ObjectivesTo assess the role of body mass index (BMI) and of the rate of weight loss as prognostic factors in amyotrophic lateral sclerosis (ALS) and to explore the clinical correlates of weight loss in the early phases of the disease.MethodsThe study cohort included all ALS patients in Piemonte/Valle d’Aosta in the 2007–2011 period. Overall survival and the probability of death/tracheostomy at 18 months (logistic regression model) were calculated.ResultsOf the 712 patients, 620 (87.1%) were included in the study. Patients ’ survival was related to the mean monthly percentage of weight loss at diagnosis (p<0.0001), but not to pre-morbid BMI or BMI at diagnosis. Spinal onset patients with dysphagia at diagnosis had a median survival similar to bulbar onset patients. About 20% of spinal onset patients without dysphagia at diagnosis had severe weight loss and initial respiratory impairment, and had a median survival time similar to bulbar onset patients.ConclusionsThe rate of weight loss from onset to diagnosis was found to be a strong and independent prognostic factor in ALS. Weight loss was mainly due to the reduction of nutritional intake related to dysphagia, but a subgroup of spinal onset patients without dysphagia at diagnosis had a severe weight loss and an outcome similar to bulbar patients. According to our findings, we recommend that in clinical trials patients should be stratified according to the presence of dysphagia at the time of enrolment and not by site of onset of symptoms.


1999 ◽  
Vol 121 (2_suppl) ◽  
pp. P155-P155
Author(s):  
Mary Essemena A Beaver ◽  
Jeffrey N Myers ◽  
Adam S Garden ◽  
Keith Matheny

2018 ◽  
Vol 6 (3) ◽  
pp. e000644
Author(s):  
Vlad Focsaneanu ◽  
Pieter Nelissen ◽  
Simon Tappin

A two-year-old working Belgian shepherd dog was referred for diagnosis and management of a chronic cough, exercise intolerance and inspiratory stridor. A diagnosis of severe dorsal tracheal membrane redundancy was made based on radiography and tracheoscopy. Vomiting, weight loss and lethargy were also reported at initial presentation presumed secondary to dietary indiscretion, which was supported by the identification of undigested bones in the stomach on radiographs and ultrasound; these signs resolved with symptomatic treatment. The patient had previously been diagnosed with primary immune-mediated polyarthritis and had responded well to immunomodulatory medication. To correct the narrowing of the tracheal lumen, the dorsal tracheal membrane was plicated surgically, improving the tracheal diameter postoperatively. Twelve weeks later the dog had returned to full exercise, and the handler reported excellent exercise tolerance and no cough. Plication of excessive dorsal tracheal membrane is one possible treatment option for dogs with severe dorsal tracheal membrane redundancy.


2018 ◽  
Vol 41 (4) ◽  
pp. 349-355 ◽  
Author(s):  
Kenki Segami ◽  
Toru Aoyama ◽  
Kazuki Kano ◽  
Yukio Maezawa ◽  
Tetsushi Nakajima ◽  
...  

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