scholarly journals Multiple spontaneous coronary artery dissections associated with intravenous daunorubicin treatment for acute myelocytic leukaemia: a case report

2020 ◽  
Author(s):  
Do Van Chien ◽  
Pham Dang Hai ◽  
Le Thi Nhung ◽  
Pham Truong Son
Keyword(s):  
Coronary Artery ◽  
Rare Condition ◽  
Artery Dissection ◽  
Second Phase ◽  
Coronary Artery Dissection ◽  
Coronary Catheterization ◽  
Myelocytic Leukaemia ◽  
Obtuse Marginal ◽  
Induction Cycle ◽  
Acute Myelocytic Leukaemia

Abstract Background Multiple spontaneous coronary artery dissection (SCAD) is a rare condition which may lead to serious consequences such as sudden cardiac death, acute myocardial infarction (AMI), and acute heart failure. Case summary In this paper, we report the case of a 57-year-old woman with acute myelocytic leukaemia who was undergoing her second phase of chemotherapy. After the first induction cycle of intravenous infusion of daunorubicin, the patient experienced chest pain, shortness of breath, and low blood pressure. The electrocardiograms revealed significant ST-elevation in the D1, aVL, and V2–V6 leads, which indicated AMI. Coronary catheterization showed spontaneous coronary dissection in the mid-left descending coronary artery and first obtuse marginal artery of the circumflex. The patient died immediately. Discussion This is the first reported case of multiple SCAD associated with intravenous (IV) daunorubicin infusion. We also reviewed the literature and proposed the mechanism of this complication.

scholarly journals Recurrent Spontaneous Coronary Artery Dissection in 4 Vascular Territories

2018 ◽  
Vol 45 (2) ◽  
pp. 106-109
Author(s):  
Nader Makki ◽  
Poorvi Dalal ◽  
Quinn Capers ◽  
Ernest Mazzaferri ◽  
Talal Attar
Keyword(s):  
Coronary Artery ◽  
Artery Bypass ◽  
Premenopausal Women ◽  
Rare Condition ◽  
Artery Dissection ◽  
Spontaneous Coronary Artery Dissection ◽  
Coronary Artery Dissection ◽  
Coronary Syndrome ◽  
Coronary Events ◽  
Multiple Episodes

Spontaneous coronary artery dissection, a rare cause of acute coronary syndrome, is due to nonatherosclerotic coronary events and is probably underrecognized as a cause of myocardial infarction. The condition typically affects premenopausal women who are otherwise healthy. Among more than 1,200 reported cases, recurrent dissection has been described 63 times, and only 3 reports have documented multiple episodes of dissection involving different vascular territories. We present the case of a woman in her 30s who, over a 9-year period, presented 4 times with coronary dissection in different vascular territories. She was first treated conservatively, then with stents, and ultimately by means of coronary artery bypass grafting. In addition to this case, we discuss this rare condition and its management.

scholarly journals Not Your Common Athletic Heart Problem: Using Coronary CTA to Visualize Spontaneous Coronary Artery Dissection

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Padma Shenoy ◽  
Taher Tayeb ◽  
Pedro Covas ◽  
Nardos Temesgen ◽  
Cynthia Tracy
Keyword(s):  
Coronary Artery ◽  
Young Patients ◽  
Reference Value ◽  
Left Ventricular ◽  
Artery Dissection ◽  
Heart Catheterization ◽  
Spontaneous Coronary Artery Dissection ◽  
Coronary Artery Dissection ◽  
Coronary Catheterization ◽  
Left Anterior Descending Artery

A 19-year-old healthy male collegiate athlete presented with typical anginal symptoms after running a 5K race. He had complained of similar symptoms off and on for the past month. On presentation, troponin was 0.12 ng/ml (reference value < 0.01 ng/ml), which peaked at 17.7 ng/ml and CK-MB was 28.71 IU/L (reference value < 25 IU/L). ECG showed diffuse biphasic T-waves. Coronary computed tomography angiogram (cCTA) demonstrated a 1.5 cm dissection in the left anterior descending artery and a 1.9 × 1.8  cm attenuation defect in the left ventricular apex consistent with thrombus. Subsequent coronary catheterization confirmed dissection of the left anterior descending artery. Spontaneous coronary artery dissection (SCAD) is a rare phenomenon. Diagnosis can be made through noninvasive measures but is usually done through left heart catheterization. In young patients who present with an NSTEMI, clinical suspicion for SCAD among other conditions should be raised. Additionally, recognizing that complications such as intracardiac thrombi can occur in SCAD is critical in ensuring appropriate therapy.

scholarly journals A tale of two SCADs: Spontaneous coronary artery dissection series

2021 ◽  
Vol 9 (37) ◽  
pp. 70-73
Author(s):  
Sanjana Rao ◽  
Nitish Mittal ◽  
Mohammad M Ansari
Keyword(s):  
Chest Pain ◽  
Coronary Artery ◽  
Intramural Hematoma ◽  
Rare Condition ◽  
Artery Dissection ◽  
Spontaneous Coronary Artery Dissection ◽  
Shortness Of Breath ◽  
Coronary Artery Dissection ◽  
Coronary Artery Angiography ◽  
Associated Symptoms

Spontaneous coronary artery dissection (SCAD), a relatively rare condition, occurs when a tear is present in the coronary artery walls, slowing the flow of blood due to potential clotting. Most patients show symptoms of chest pain or shortness of breath; however, SCAD is seen mostly in relatively young and healthy women with minimal past medical history. Within this report, we present two female SCAD patients and the etiology of a SCAD case, including a complicated diagnosis and treatment. We describe a 33-year-old woman and a 40-year-old woman both presenting to the emergency department with chest pain and shortness of breath. Electrocardiogram was done and coronary artery angiography was performed on both patients, demonstrating a SCAD. Both patients were treated with aspirin, bet-blockers, and statin to relieve associated symptoms and accordingly discharged.   Key words: Spontaneous coronary artery dissection (SCAD), Female, intramural hematoma

Pregnancy-associated spontaneous coronary artery dissection: multidisciplinary management, challenges and literature review

2021 ◽  
Vol 14 (12) ◽  
pp. e244851
Author(s):  
Nnadozie Igbokwe ◽  
Jess Gomersall ◽  
Sunday Paul Ugwoke ◽  
Sean Esmonde
Keyword(s):  
Coronary Artery ◽  
Troponin T ◽  
Artery Bypass ◽  
Coronary Intervention ◽  
Left Ventricular ◽  
Artery Dissection ◽  
Coronary Artery Dissection ◽  
Vein Grafts ◽  
Severe Impairment ◽  
Obtuse Marginal

A 30-year-old woman in her second pregnancy, which was complicated by gestational diabetes mellitus. She had an uneventful spontaneous vaginal delivery at 38 weeks+3 days of gestation. Day 1 postpartum, she developed sudden chest pain radiating to her jaw and neck. Her observations were normal, and ECG showed lateral ST elevation in keeping with acute myocardial infarction. The troponin-T level was elevated at 21 ng/L at 0 hour, and >10 000 ng/L at 12 hours, respectively. Coronary angiography confirmed spontaneous dissection of the proximal left anterior descending (LAD) and proximal circumflex coronary arteries. She became unstable during percutaneous coronary intervention and consequently had a successful coronary artery bypass surgery with left saphenous vein grafts to the first obtuse marginal artery and LAD. Echocardiogram revealed moderate to severe impairment of the left ventricular function postoperatively.

scholarly journals Spontaneous Coronary Artery Dissection in the Third Trimester -- implications for investigation and delivery.

2021 ◽  
Author(s):  
Tom Paxton-Hall ◽  
Pranali Desai ◽  
Nicholas Seton ◽  
Chris Arthur
Keyword(s):  
Coronary Artery ◽  
Significant Risk ◽  
Rare Condition ◽  
Artery Dissection ◽  
Unborn Child ◽  
Spontaneous Coronary Artery Dissection ◽  
Third Trimester ◽  
Coronary Artery Dissection ◽  
Minimal Data ◽  
Clinical Considerations

Spontaneous coronary artery dissection (SCAD) is a rare condition which occurs predominantly in the postpartum period in young women. A SCAD whilst pregnant is very rare and poses significant risk to the mother and unborn child, and with minimal data on SCAD antenatally, this case highlights antepartum clinical considerations.

scholarly journals Spontaneous Coronary Artery Dissection of LM and LM- LAD artery in Peripartum or Postpartum Women with Acute Myocardial Infarction

2015 ◽  
Vol 7 (2) ◽  
pp. 153-158
Author(s):  
AHM Waliul Islam ◽  
Shams Munwar ◽  
Azfar H Bhuiyan ◽  
Shahab Uddin Talukder ◽  
AQM Reza ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Coronary Artery ◽  
Coronary Occlusion ◽  
Rare Condition ◽  
Artery Dissection ◽  
Single Coronary Artery ◽  
Spontaneous Coronary Artery Dissection ◽  
Coronary Artery Dissection ◽  
Exact Etiology

Spontaneous coronary artery dissection (SCAD) is a very rare condition which may result in sudden coronary occlusion, acute myocardial infarction and sudden cardiac death. It usually occurs in young women during pregnancy or postpartum period and in most cases it involves a single coronary artery. The exact etiology is unknown. The prognosis of SCAD is uncertain and optimal treatment is unknown. Early diagnosis and treatment are key for survival, and when identified early, mortality rate is reduced. DOI: http://dx.doi.org/10.3329/cardio.v7i2.22265 Cardiovasc. j. 2015; 7(2): 153-158

scholarly journals Heavy Lifting Causing Spontaneous Coronary Artery Dissection with Anterior Myocardial Infarction in a 54-Year-Old Woman

2016 ◽  
Vol 43 (2) ◽  
pp. 189-191 ◽  
Author(s):  
Kyriakos Yiangou ◽  
Kyriacos Papadopoulos ◽  
Chara Azina
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery ◽  
Medical Literature ◽  
Rare Condition ◽  
Strenuous Exercise ◽  
Artery Dissection ◽  
Spontaneous Coronary Artery Dissection ◽  
Coronary Artery Dissection ◽  
Anterior Myocardial Infarction ◽  
Drug Eluting

Spontaneous coronary artery dissection in association with strenuous exercise and weightlifting is rather sparsely described in the medical literature. Diagnosis and treatment of this rare condition is a challenge, but prompt recognition and appropriate early choice of angioplasty or surgery can lead to a good outcome. We report the case of a postmenopausal 54-year-old woman who presented with anterior myocardial infarction caused by spontaneous dissection of the left anterior descending coronary artery after she had lifted a heavy weight while gardening. The patient was treated successfully by means of angioplasty and the implantation of 3 drug-eluting stents. In addition to presenting the patient's case, we review the topical medical literature.

scholarly journals Bioresorbable Scaffolds in Spontaneous Coronary Artery Dissection: Long-Term Follow-Up in 4 Patients

2017 ◽  
Vol 44 (6) ◽  
pp. 405-410 ◽  
Author(s):  
Santiago Jesús Camacho Freire ◽  
Antonio Enrique Gómez Menchero ◽  
Jessica Roa Garrido ◽  
Javier León Jiménez ◽  
Rosa Cardenal Piris ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Rare Condition ◽  
Long Term Results ◽  
Artery Dissection ◽  
Spontaneous Coronary Artery Dissection ◽  
Coronary Artery Dissection ◽  
Young Females ◽  
Coronary Syndrome ◽  
Long Term Follow Up

Spontaneous coronary artery dissection is a rare condition, and diagnosis and treatment are challenging among patients who present with acute coronary syndrome. Typically, the condition affects young females who have no underlying atherosclerotic disease. To date, few cases of bioresorbable scaffold implantation for the treatment of spontaneous coronary artery dissection have been reported. Therefore, we describe the cases of 4 patients whom we treated with scaffolds. We evaluated the long-term results by using intravascular ultrasound and optical coherence tomographic scanning.

Sign in / Sign up

Export Citation Format

Share Document