scholarly journals Case study: a patient with dilated cardiomyopathy, left bundle branch block, recurrent syncope and heart failure

2002 ◽  
Vol 4 (suppl_D) ◽  
pp. D132-D133
Author(s):  
D Böcker ◽  
G Breithardt
Keyword(s):  
Heart Failure ◽  
Dilated Cardiomyopathy ◽  
Left Bundle Branch Block ◽  
Bundle Branch Block

scholarly journals Acute Heart Failure Due to Transient Left Ventricular Dyssynchrony: Case Study

2010 ◽  
Vol 19 (3) ◽  
pp. e12-e14 ◽  
Author(s):  
Matthieu Jourdain ◽  
Jean Jacques Bauchart ◽  
Jean Luc Auffray ◽  
Thierry H. LeJemtel ◽  
Philippe Asseman ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Left Bundle Branch Block ◽  
Systolic Dysfunction ◽  
Left Ventricular ◽  
Left Ventricular Dyssynchrony ◽  
Beta Blockade ◽  
Bundle Branch Block ◽  
Ventricular Dyssynchrony

This case study describes an unusual cause of acute heart failure that resolved with early beta-blockade therapy. A 52-year-old woman who had acute heart failure with severe left ventricular systolic dysfunction and left bundle branch block was admitted to a university medical center. Contrast-enhanced magnetic resonance images of the heart did not show any evidence of myocardial infarction or myocarditis. Rate-related left bundle branch block and subsequent left ventricular dyssynchrony resulted in acute systolic dysfunction that resolved with beta-blockade therapy that allowed heart rate control and narrowing of the QRS complex. Of note, the use of inotropic agents would have dramatically worsened the cardiac condition.

scholarly journals Associations between left bundle branch block with different PR intervals, QRS durations, heart rates and the risk of heart failure: a register-based cohort study using ECG data from the primary care setting

Open Heart ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. e001425
Author(s):  
Marc Meller Søndergaard ◽  
Johannes Riis ◽  
Karoline Willum Bodker ◽  
Steen Møller Hansen ◽  
Jesper Nielsen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Primary Care ◽  
Heart Rate ◽  
Left Bundle Branch Block ◽  
Bundle Branch Block ◽  
Increased Risk ◽  
Pr Interval ◽  
Qrs Duration ◽  
The Impact

AimLeft bundle branch block (LBBB) is associated with an increased risk of heart failure (HF). We assessed the impact of common ECG parameters on this association using large-scale data.Methods and resultsUsing ECGs recorded in a large primary care population from 2001 to 2011, we identified HF-naive patients with a first-time LBBB ECG. We obtained information on sex, age, emigration, medication, diseases and death from Danish registries. We investigated the association between the PR interval, QRS duration, and heart rate and the risk of HF over a 2-year follow-up period using Cox regression analysis.Of 2471 included patients with LBBB, 464 (18.8%) developed HF during follow-up. A significant interaction was found between QRS duration and heart rate (p<0.01), and the analyses were stratified on these parameters. Using a QRS duration <150 ms and a heart rate <70 beats per minute (bpm) as the reference, all groups were statistically significantly associated with the development of HF. Patients with a QRS duration ≥150 ms and heart rate ≥70 bpm had the highest risk of developing HF (HR 3.17 (95% CI 2.41 to 4.18, p<0.001). There was no association between the PR interval and HF after adjustment.ConclusionProlonged QRS duration and higher heart rate were associated with increased risk of HF among primary care patients with LBBB, while no association was observed with PR interval. Patients with LBBB with both a prolonged QRS duration (≥150 ms) and higher heart rate (≥70 bpm) have the highest risk of developing HF.

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