scholarly journals ESC working group position paper on myocardial infarction with non-obstructive coronary arteries

2016 ◽  
pp. ehw149 ◽  
Author(s):  
Stefan Agewall ◽  
John F. Beltrame ◽  
Harmony R. Reynolds ◽  
Alexander Niessner ◽  
Giuseppe Rosano ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Arteries ◽  
Working Group ◽  
Position Paper ◽  
Group Position

scholarly journals Correction to: Guidelines for the management of myocardial infarction/injury with non-obstructive coronary arteries (MINOCA): a position paper from the Dutch ACS working group

2019 ◽  
Vol 28 (1) ◽  
pp. 59-59
Author(s):  
T. F. S. Pustjens ◽  
Y. Appelman ◽  
P. Damman ◽  
J. M. ten Berg ◽  
J. W. Jukema ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Coronary Arteries ◽  
Working Group ◽  
Position Paper ◽  
Coronary Syndrome ◽  
Link Type

Correction to:Neth Heart J 201910.1007/s12471-019-01344-6The reference to the term acute coronary syndrome with normal or near-normal (non-obstructive) coronary arteries (ACSNNOCA) from Manolis et al. (2018) was inadvertently omitted to the original published article. Therefore, …

scholarly journals Guidelines for the management of myocardial infarction/injury with non-obstructive coronary arteries (MINOCA): a position paper from the Dutch ACS working group

2019 ◽  
Vol 28 (3) ◽  
pp. 116-130 ◽  
Author(s):  
T. F. S. Pustjens ◽  
Y. Appelman ◽  
P. Damman ◽  
J. M. ten Berg ◽  
J. W. Jukema ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Arteries ◽  
Working Group ◽  
Diagnostic Algorithm ◽  
Position Paper ◽  
Netherlands Society ◽  
Psychosocial Status ◽  
Coronary Syndrome ◽  
Cardiac Disorders ◽  
The Many

AbstractPatients with myocardial infarction and non-obstructive coronary arteries (MINOCA), defined as angiographic stenosis <50%, represent a conundrum given the many potential underlying aetiologies. Possible causes of MINOCA can be subdivided into coronary, myocardial and non-cardiac disorders. MINOCA is found in up to 14% of patients presenting with an acute coronary syndrome. Clinical outcomes including mortality, and functional and psychosocial status, are comparable to those of patients with myocardial infarction and obstructive coronary arteries. However, many uncertainties remain regarding the definition, clinical features and management of these patients. This position paper of the Dutch ACS working group of the Netherlands Society of Cardiology aims to stress the importance of considering MINOCA as a dynamic working diagnosis and to guide the clinician in the management of patients with MINOCA by proposing a clinical diagnostic algorithm.

scholarly journals Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology

2017 ◽  
Vol 114 (1) ◽  
pp. 19-34 ◽  
Author(s):  
Joost Petrus Gerardus Sluijter ◽  
Sean Michael Davidson ◽  
Chantal M Boulanger ◽  
Edit Iren Buzás ◽  
Dominique Paschalis Victor de Kleijn ◽  
...  
Keyword(s):  
Extracellular Vesicles ◽  
Working Group ◽  
Position Paper ◽  
Paracrine Effects ◽  
Group Position ◽  
Wide Range ◽  
Potential Alternative ◽  
Number Of Publications ◽  
European Society Of Cardiology ◽  
Regenerative Therapies

AbstractExtracellular vesicles (EVs)—particularly exosomes and microvesicles (MVs)—are attracting considerable interest in the cardiovascular field as the wide range of their functions is recognized. These capabilities include transporting regulatory molecules including different RNA species, lipids, and proteins through the extracellular space including blood and delivering these cargos to recipient cells to modify cellular activity. EVs powerfully stimulate angiogenesis, and can protect the heart against myocardial infarction. They also appear to mediate some of the paracrine effects of cells, and have therefore been proposed as a potential alternative to cell-based regenerative therapies. Moreover, EVs of different sources may be useful biomarkers of cardiovascular disease identities. However, the methods used for the detection and isolation of EVs have several limitations and vary widely between studies, leading to uncertainties regarding the exact population of EVs studied and how to interpret the data. The number of publications in the exosome and MV field has been increasing exponentially in recent years and, therefore, in this ESC Working Group Position Paper, the overall objective is to provide a set of recommendations for the analysis and translational application of EVs focussing on the diagnosis and therapy of the ischaemic heart. This should help to ensure that the data from emerging studies are robust and repeatable, and optimize the pathway towards the diagnostic and therapeutic use of EVs in clinical studies for patient benefit.

IEEE ITRW Working Group Position Paper-Materials and Devices: WBG and UWBG Materials and Devices Are Examined in a New Working Group

2018 ◽  
Vol 5 (2) ◽  
pp. 45-48 ◽  
Author(s):  
Victor Veliadis ◽  
Robert Kaplar ◽  
Jon Zhang ◽  
Mietek Bakowski ◽  
Sameh Khalil ◽  
...  
Keyword(s):  
Working Group ◽  
Position Paper ◽  
Group Position

MYOCARDIAL INFARCTION WITH NON-OBSTRUCTIVE CORONARY ARTERIES (MINOCA) ACCORDING TO DEFINITIONS OF 2016 ESC POSITION PAPER: CLINICAL PROFILE AND PROGNOSIS

2018 ◽  
Vol 71 (11) ◽  
pp. A19 ◽  
Author(s):  
Barbara Izquierdo Coronel ◽  
Javier Lopez Pais ◽  
David Galan Gil ◽  
Maria Jesus Espinosa Pascual ◽  
Paula Awamleh ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Arteries ◽  
Position Paper ◽  
Clinical Profile

scholarly journals IEEE ITRW Working Group Position Paper-Packaging and Integration: Unlocking the Full Potential of Wide-Bandgap Devices

2018 ◽  
Vol 5 (2) ◽  
pp. 26-33 ◽  
Author(s):  
Mark Johnson ◽  
Peter R. Wilson ◽  
Lee Empringham ◽  
Liliana De Lillo
Keyword(s):  
Working Group ◽  
Wide Bandgap ◽  
Position Paper ◽  
Full Potential ◽  
Group Position

scholarly journals Left atrial reservoir strain is reduced in patients with myocardial infarction with non-obstructive coronary arteries

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
M Malaty ◽  
H H L Chen ◽  
G Gan
Keyword(s):  
Myocardial Infarction ◽  
Coronary Arteries ◽  
Left Atrial ◽  
Speckle Tracking ◽  
Global Longitudinal Strain ◽  
Strain Analysis ◽  
Left Ventricular ◽  
Funding Sources ◽  
Group Position ◽  
Lv Dysfunction

Abstract Background Myocardial infarction with non-obstructive coronary arteries (MINOCA) represents a management conundrum given the poorly understood pathogenic mechanisms. In recent years, novel echocardiographic measures such as deformation/strain analysis have enabled early identification of left atrial (LA) remodelling and dysfunction which take place prior to structural alterations. LA dysfunction is an important biomarker of cardiovascular disease and an independent predictor of atrial arrhythmias which may play a fundamental role in the pathogenesis of MINOCA. Purpose The goal of our study was to evaluate and characterise LA function by speckle tracking strain echocardiography in patients with MINOCA. Methods Patients admitted to our institution with acute myocardial infarction were assessed and those diagnosed with MINOCA who underwent transthoracic echocardiogram (TTE) within 48-hours of their coronary angiogram were included. Diagnosis of MINOCA was based on the 2017 ESC working group position paper on myocardial infarction with non-obstructive coronary arteries. Two-dimensional speckle tracking strain analysis of the LA and left ventricle (LV) was performed offline using vendor independent software (TomTec Arena). Clinical and echocardiographic measures were compared to healthy controls identified from our echocardiography database. We excluded patients with history of atrial fibrillation, heart failure and LV dysfunction (LVEF &lt;50%). Results The cohort consisted of 82 patients; 41 patients with MINOCA were compared to 41 age and sex matched controls (61% male, mean age 51±12.8 years). At baseline, patients with MINOCA had a higher prevalence of modifiable vascular risk factors including smoking, hypertension and diabetes (p&lt;0.001 for all). Of the echocardiographic parameters, no differences in left ventricular (LV) parameters including LV global longitudinal strain (p=0.463), indexed LV mass (p=0.084) and the E/e' (p=0.391) was appreciated. Though there was no difference in LA volumes or volumetric parameters of LA function (LAEF; p=0.328), patients with MINOCA had a lower LA reservoir strain (29.7±8.5% vs 33.2±6.5%; p=0.04; 95% CI 0.32–5.33). Conclusion Patients with MINOCA demonstrated lower LASr despite normal LV and LA volumes. This suggests that LA dysfunction may play a role in the pathogenesis of MINOCA. Further studies are required to evaluate the significance of our findings. FUNDunding Acknowledgement Type of funding sources: None.

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