scholarly journals Current state of scientific evidence on Internet-based interventions for the treatment of depression, anxiety, eating disorders and substance abuse: an overview of systematic reviews and meta-analyses

Author(s):  
C Taylor ◽  
Andrea K Graham ◽  
Rachael E Flatt ◽  
Karin Waldherr ◽  
Ellen E Fitzsimmons-Craft

Abstract Background ICare represents a consortium of European Investigators examining the effects of online mental health care for a variety of common mental health disorders provided in a variety of settings. This article provides an overview of the evidence of effectiveness for Internet-based treatment for four common mental health disorders that are the focus of much of this work: depression, anxiety, substance abuse and eating disorders. Methods The overview focused primarily on systematic reviews and meta-analyses identified through PubMed (Ovid) and other databases and published in English. Given the large number of reviews specific to depression, anxiety, substance abuse and/or eating disorders, we did not focus on reviews that examined the effects of Internet-based interventions on mental health disorders in general. Each article was reviewed and summarized by one of the senior authors, and this review was then reviewed by the other senior authors. We did not address issues of prevention, cost-effectiveness, implementation or dissemination, as these are addressed in other reviews in this supplement. Results Across Internet-based intervention studies addressing depression, anxiety, substance abuse and eating disorders primarily among adults, almost all reviews and meta-analyses found that these interventions successfully reduce symptoms and are efficacious treatments. Generally, effect sizes for Internet-based interventions treating eating disorders and substance abuse are lower compared with interventions for depression and anxiety. Conclusions Given the effectiveness of Internet-based interventions to reduce symptoms of these common mental health disorders, efforts are needed to examine issues of how they can be best disseminated and implemented in a variety of health care and other settings.

BJPsych Open ◽  
2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Zach Walsh ◽  
Ozden Merve Mollaahmetoglu ◽  
Joseph Rootman ◽  
Shannon Golsof ◽  
Johanna Keeler ◽  
...  

Background In the past two decades, subanaesthetic doses of ketamine have been demonstrated to have rapid and sustained antidepressant effects, and accumulating research has demonstrated ketamine's therapeutic effects for a range of psychiatric conditions. Aims In light of these findings surrounding ketamine's psychotherapeutic potential, we systematically review the extant evidence on ketamine's effects in treating mental health disorders. Method The systematic review protocol was registered in PROSPERO (identifier CRD42019130636). Human studies investigating the therapeutic effects of ketamine in the treatment of mental health disorders were included. Because of the extensive research in depression, bipolar disorder and suicidal ideation, only systematic reviews and meta-analyses were included. We searched Medline and PsycINFO on 21 October 2020. Risk-of-bias analysis was assessed with the Cochrane Risk of Bias tools and A Measurement Tool to Assess Systematic Reviews (AMSTAR) Checklist. Results We included 83 published reports in the final review: 33 systematic reviews, 29 randomised controlled trials, two randomised trials without placebo, three non-randomised trials with controls, six open-label trials and ten retrospective reviews. The results were presented via narrative synthesis. Conclusions Systematic reviews and meta-analyses provide support for robust, rapid and transient antidepressant and anti-suicidal effects of ketamine. Evidence for other indications is less robust, but suggests similarly positive and short-lived effects. The conclusions should be interpreted with caution because of the high risk of bias of included studies. Optimal dosing, modes of administration and the most effective forms of adjunctive psychotherapeutic support should be examined further.


2019 ◽  
Vol 1 (1) ◽  
pp. 67
Author(s):  
Ioanna V. Papathanasiou ◽  
Evangelos C. Fradelos ◽  
Sofia Kastanidou ◽  
Konstantinos Tsaras ◽  
Francesca Pozzi ◽  
...  

Concerning community mental health care, current studies’ results have shown many benefits for individuals that are suffering from mental disorders and their families also, of the nursing care that is provided from Family and Community Nurses. According to these results the patient – centered, adequate and continuing nursing care is an essential condition for better health outcomes of chronic mental health disorders, can reduce relapses and hospitalizations, saving significant fund


2020 ◽  
Vol 3 (3) ◽  
pp. e201210
Author(s):  
Jose F. Figueroa ◽  
Jessica Phelan ◽  
E. John Orav ◽  
Vikram Patel ◽  
Ashish K. Jha

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