GENETIC LOADS IN HETEROGENEOUS ENVIRONMENTS

Genetics ◽  
1975 ◽  
Vol 80 (3) ◽  
pp. 621-635
Author(s):  
Charles E Taylor

ABSTRACT A model of population structure in heterogeneous environments is described with attention focused on genetic variation at a single locus. The existence of equilibria at which there is no genetic load is examined.—The absolute fitness of any genotype is regarded as a function of location in the niche space and the population density at that location. It is assumed that each organism chooses to live in that habitat in which it is most fit ("optimal habitat selection").—Equilibria at which there is no segregational load ("loadless equilibria") may exist. Necessary and sufficient conditions for the existence of such equilibria are very weak. If there is a sufficient amount of dominance or area in which the alleles are selectively neutral, then there exist equilibria without segregational loads. In the N, p phase plane defined by population size, N, and gene frequency, p, these equilibria generally consist of a line segment which is parallel to the p axis. These equilibria are frequently stable.

Genetics ◽  
1976 ◽  
Vol 83 (4) ◽  
pp. 887-894
Author(s):  
Charles E Taylor

ABSTRACT A model of population structure in heterogeneous environments is described and conditions sufficient for maintaining a polymorphism are derived. The absolute fitness of any genotype is regarded as a function of location in the niche space and the population density at that location. Two modes of habitat selection are examined: (1) organisms are distributed uniformly over the environment; and (2) each organism selects to occupy that habitat in which it is most fit ("optimal habitant selection").—Sufficient conditions for maintenance of genetic polymorphisms are derived for both models. In populations which do not practice habitat selection heterozygote superiority averaged over the environment is sufficient to guarantee the existence of polymorphisms. Comparable conditions for populations which practice optimal habitat selection are much less restrictive. If the heterozygotes are superior to one homozygote in any one part of the niche and to the other homozygote in any other part of the niche then a polymorphism will be defined.—A positive correlation between genetic and environmental variation follows from the model with habitat selection, but not from the other. The adaptive significance of polymorphisms thus depends on how animals behave.


1986 ◽  
Vol 23 (04) ◽  
pp. 851-858 ◽  
Author(s):  
P. J. Brockwell

The Laplace transform of the extinction time is determined for a general birth and death process with arbitrary catastrophe rate and catastrophe size distribution. It is assumed only that the birth rates satisfyλ0= 0,λj> 0 for eachj> 0, and. Necessary and sufficient conditions for certain extinction of the population are derived. The results are applied to the linear birth and death process (λj=jλ, µj=jμ) with catastrophes of several different types.


2008 ◽  
pp. 134-151
Author(s):  
A. Shastitko ◽  
M. Ovchinnikov

The article proposes an approach to the analysis of social change and contributes to the clarification of concepts of economic policy. It deals in particular with the notion of "change of system". The author considers positive and normative aspects of the analysis of capitalist and socialist systems. The necessary and sufficient conditions for the system to be changed are introduced, their fulfillment is discussed drawing upon the historical and statistical data. The article describes both economic and political peculiarities of the transitional period in different countries, especially in Eastern Europe.


2020 ◽  
Vol 52 (4) ◽  
Author(s):  
Min Lu ◽  
Huaishan Zhang ◽  
Huaming An ◽  
Wen Zhou

2020 ◽  
pp. 77-90
Author(s):  
V.D. Gerami ◽  
I.G. Shidlovskii

The article presents a special modification of the EOQ formula and its application to the accounting of the cargo capacity factor for the relevant procedures for optimizing deliveries when renting storage facilities. The specified development will allow managers to take into account the following process specifics in the format of a simulated supply chain when managing inventory. First of all, it will allow considering the most important factor of cargo capacity when optimizing stocks. Moreover, this formula will make it possible to find the optimal strategy for the supply of goods if, also, it is necessary to take into account the combined effect of several factors necessary for practice, which will undoubtedly affect decision-making procedures. Here we are talking about the need for additional consideration of the following essential attributes of the simulated cash flow of the supply chain: 1) time value of money; 2) deferral of payment of the cost of the order; 3) pre-agreed allowable delays in the receipt of revenue from goods sold. Developed analysis and optimization procedures have been implemented to models of this type that are interesting and important for a business. This — inventory management systems, the format of which is related to the special concept of efficient supply. We are talking about models where the presence of the specified delays for the outgoing cash flows allows you to pay for the order and the corresponding costs of the supply chain from the corresponding revenue on the re-order interval. Accordingly, the necessary and sufficient conditions are established based on which managers will be able to identify models of the specified type. The purpose of the article is to draw the attention of managers to real opportunities to improve the efficiency of inventory management systems by taking into account these factors for a simulated supply chain.


2020 ◽  
Vol 17 (3) ◽  
pp. 313-324
Author(s):  
Sergii Chuiko ◽  
Ol'ga Nesmelova

The study of the differential-algebraic boundary value problems, traditional for the Kiev school of nonlinear oscillations, founded by academicians M.M. Krylov, M.M. Bogolyubov, Yu.A. Mitropolsky and A.M. Samoilenko. It was founded in the 19th century in the works of G. Kirchhoff and K. Weierstrass and developed in the 20th century by M.M. Luzin, F.R. Gantmacher, A.M. Tikhonov, A. Rutkas, Yu.D. Shlapac, S.L. Campbell, L.R. Petzold, Yu.E. Boyarintsev, V.F. Chistyakov, A.M. Samoilenko, O.A. Boichuk, V.P. Yacovets, C.W. Gear and others. In the works of S.L. Campbell, L.R. Petzold, Yu.E. Boyarintsev, V.F. Chistyakov, A.M. Samoilenko and V.P. Yakovets were obtained sufficient conditions for the reducibility of the linear differential-algebraic system to the central canonical form and the structure of the general solution of the degenerate linear system was obtained. Assuming that the conditions for the reducibility of the linear differential-algebraic system to the central canonical form were satisfied, O.A.~Boichuk obtained the necessary and sufficient conditions for the solvability of the linear Noetherian differential-algebraic boundary value problem and constructed a generalized Green operator of this problem. Based on this, later O.A. Boichuk and O.O. Pokutnyi obtained the necessary and sufficient conditions for the solvability of the weakly nonlinear differential algebraic boundary value problem, the linear part of which is a Noetherian differential algebraic boundary value problem. Thus, out of the scope of the research, the cases of dependence of the desired solution on an arbitrary continuous function were left, which are typical for the linear differential-algebraic system. Our article is devoted to the study of just such a case. The article uses the original necessary and sufficient conditions for the solvability of the linear Noetherian differential-algebraic boundary value problem and the construction of the generalized Green operator of this problem, constructed by S.M. Chuiko. Based on this, necessary and sufficient conditions for the solvability of the weakly nonlinear differential-algebraic boundary value problem were obtained. A typical feature of the obtained necessary and sufficient conditions for the solvability of the linear and weakly nonlinear differential-algebraic boundary-value problem is its dependence on the means of fixing of the arbitrary continuous function. An improved classification and a convergent iterative scheme for finding approximations to the solutions of weakly nonlinear differential algebraic boundary value problems was constructed in the article.


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