scholarly journals 1544Baseline predictors of attrition in a randomised controlled trial of treatments for people with recurrent binge eating episodes associated to overweight or obesity

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Haider Mannan ◽  
Phillipa Hay
Keyword(s):  
Body Weight ◽  
Eating Disorder ◽  
Bulimia Nervosa ◽  
Binge Eating ◽  
Lower Body ◽  
Treatment Attrition ◽  
Lower Body Weight ◽  
Lower Treatment ◽  
Overweight Or Obesity

Abstract Purpose Understanding the high rate of treatment attrition in trials of people with eating disorders is important as it can compromise the quality of the trials. In clinical practice, it may also contribute to illness chronicity, relapse, and costs. Thus, we investigated factors associated with treatment attrition to a new manualised psychotherapy HAPIFED compared to CBT-E, for individuals with Bulimia Nervosa or Binge Eating Disorder comorbid with overweight or obesity. Methods In total, 98 participants were recruited with 50 randomised to HAPIFED and 48 to the control intervention CBT-E, all administered in groups of up to 10 participants. An investigator external to the site conducted the random allocation, which was concealed from the statistician involved in the analysis, and known only to the therapists until the finalization of the 12-month follow-up after the end of active treatment. Three scenarios in the timeline treatment of a total of 30 sessions were assessed: 33% or 60% or 75% of presence. Logistic regression analysis was performed to find the correlates of attrition. Results None of the six variables - frequency of binge eating episodes, purging, eating disorder symptom severity, weight, illness duration and mental health-related quality of life - significantly predicted attrition at 33%, but longer illness duration predicted lower treatment attrition at both 60% and 75% presence of the interventions. Also for 75% presence, lower body weight predicted lower treatment attrition. Conclusions Lower attrition due to late treatment completion was associated with longer binge eating illness length and a lower body weight. More research is needed to recognize factors that may interfere with engagement in treatments aiming to avoid early dropout. Keywords binge eating disorder, bulimia nervosa, cognitive therapy, obesity, patient dropout Trial registration US National Institutes of Health clinical trial registration number NCT02464345, date of registration 1 June 2015.

scholarly journals Baseline Predictors of Attrition in a Randomised Controlled Trial of a New Group Psychological Intervention for People with Recurrent Binge Eating Episodes Associated to Overweight or Obesity

2021 ◽  
Author(s):  
Haider Mannan ◽  
Marly Amorim Palavras ◽  
Phillipa Hay ◽  
Angelica Claudino
Keyword(s):  
Body Weight ◽  
Eating Disorder ◽  
Binge Eating ◽  
Trial Registration ◽  
Lower Body ◽  
Treatment Attrition ◽  
Lower Body Weight ◽  
Lower Treatment ◽  
Overweight Or Obesity

Abstract Purpose: Understanding the high rate of treatment attrition in trials of people with eating disorders is important as it can compromise the quality of the trials. In clinical practice, it may also contribute to illness chronicity, relapse, and costs. Thus, we investigated factors associated with treatment attrition to a new manualised psychotherapy HAPIFED compared to CBT-E, for individuals with Bulimia Nervosa or Binge Eating Disorder comorbid with overweight or obesity.Methods: In total, 98 participants were recruited with 50 randomised to HAPIFED and 48 to the control intervention CBT-E, all administered in groups of up to 10 participants. An investigator external to the site conducted the random allocation, which was concealed from the statistician involved in the analysis, and known only to the therapists until the finalization of the 12-month follow-up after the end of active treatment. Three scenarios in the timeline treatment of a total of 30 sessions were assessed: 33% or 60% or 75% of presence. Logistic regression analysis was performed to find the correlates of attrition.Results: None of the six variables - frequency of binge eating episodes, purging, eating disorder symptom severity, weight, illness duration and mental health-related quality of life - significantly predicted attrition at 33%, but longer illness duration predicted lower treatment attrition at both 60% and 75% presence of the interventions. Also for 75% presence, lower body weight predicted lower treatment attrition. Conclusions: Lower attrition due to late treatment completion was associated with longer binge eating illness length and a lower body weight. More research is needed to recognize factors that may interfere with engagement in treatments aiming to avoid early dropout.Trial registration: US National Institutes of Health clinical trial registration number NCT02464345, date of registration 1 June 2015.

scholarly journals Baseline predictors of attrition in a randomised controlled trial of treatments for people with recurrent binge eating episodes associated to overweight or obesity

2020 ◽  
Author(s):  
Haider Mannan ◽  
Marly Palavras ◽  
phillipa Hay ◽  
Angelica Claudinho
Keyword(s):  
Eating Disorder ◽  
Binge Eating ◽  
Controlled Trial ◽  
High Rate ◽  
Random Allocation ◽  
Treatment Attrition ◽  
Clinical Trial Registration ◽  
Illness Duration ◽  
Lower Treatment

Abstract PurposeUnderstanding the high rate of treatment attrition in trials of people with eating disorders is important as it can compromise the quality of the trials. In clinical practice, it may also contribute to illness chronicity, relapse, and costs. Thus, we investigated factors associated with treatment attrition to a new manualised psychotherapy HAPIFED compared to CBT-E, for individuals with Bulimia Nervosa or Binge Eating Disorder comorbid with overweight or obesity.MethodsIn total, 98 participants were recruited with half randomised to HAPIFED and half to the control intervention CBT-E, all administered in groups of up to 10 participants. An investigator external to the site conducted the random allocation, which was concealed from the statistician involved in the analysis, and known only to the therapists until the finalization of the 12-month follow-up after the end of active treatment. Three scenarios in the timeline treatment of a total of 30 sessions were assessed: 33% or 60% or 75% of presence. Logistic regression analysis was performed to find the correlates of attrition.ResultsNone of the six variables - frequency of binge eating episodes, purging, eating disorder symptom severity, weight, illness duration and mental health-related quality of life - significantly predicted attrition at 33%, but longer illness duration predicted lower treatment attrition at both 60% and 75% presence of the interventions. Also for 75% presence, lower weight predicted lower treatment attrition.ConclusionsLate treatment dropout was associated with lower illness length and a higher weight. More research is needed to recognize factors that may interfere with engagement in treatments aiming to avoid early dropout.Trial registrationUS National Institutes of Health clinical trial registration number NCT02464345, date of registration 1 June 2015.

scholarly journals Baseline Predictors of Adherence in a Randomised Controlled Trial of a New Group Psychological Intervention for People with Recurrent Binge Eating Episodes Associated to Overweight or Obesity

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4171
Author(s):  
Haider Mannan ◽  
Marly Amorim Palavras ◽  
Angélica Claudino ◽  
Phillipa Hay
Keyword(s):  
Eating Disorders ◽  
Body Weight ◽  
Eating Disorder ◽  
Binge Eating ◽  
Treatment Adherence ◽  
Binge Eating Disorder ◽  
Behavioural Therapy ◽  
Illness Duration ◽  
Cognitive Behavioural

Purpose: Understanding the high rate of treatment adherence in trials of people with eating disorders is important as it can compromise the quality of the trials. In clinical practice, it may also contribute to illness chronicity, relapse, and costs. Thus, we investigated factors associated with adherence to a new treatment HAPIFED, which integrates cognitive behavioural therapy having extended sessions with body weight loss therapy compared to cognitive behavioural therapy with extended sessions alone, for individuals with Bulimia Nervosa or Binge Eating Disorder or other eating disorders comorbid with overweight or obesity. Methods: In total, 98 participants having bulimia nervosa, binge eating disorder and other specified and unspecified eating disorders were recruited with 50 randomised to HAPIFED and 48 to the control intervention CBT-E, all administered in groups of up to 10 participants. An investigator external to the site conducted the random allocation, which was concealed from the statistician involved in the analysis, and known only to the therapists until the finalization of the 12-month follow-up after the end of active treatment. Three scenarios in the timeline treatment of a total of 30 sessions were assessed: 33% or 60% or 75% of presence. Mixed-effects logistic regression analysis was performed to find the correlates of adherence after adjusting for clustering by number of group participants. To account for heterogeneity by types of eating disorders in the sample, the latter variable was considered as a control factor in the models. A subgroup analysis was performed for those with binge eating disorder as this was the largest (N = 66) eating disorder group. Results: None of the six variables—frequency of binge eating episodes, purging, eating disorder symptom severity, weight, illness duration and mental health-related quality of life—significantly predicted adherence at 33%, but longer illness duration predicted higher treatment adherence at both 60% and 75% presence of the interventions. Also for 75% presence, higher body weight predicted lower treatment adherence. For the subgroup analysis, those having higher illness duration had significantly higher odds of treatment adherence for 60% and 75% of the sessions. Conclusions: Higher adherence due to late treatment completion was associated with longer binge eating illness length and a lower body weight. More research is needed to recognize factors that may interfere with engagement in treatments aiming to avoid early dropout.

Influence of temperature, photoperiod, and food on the speed of development, longevity, fecundity, and other qualities of the Diamond-Back moth Plutella Maculipennis (Curtis) (Lepidoptera: Tineidae).

1955 ◽  
Vol 3 (2) ◽  
pp. 185 ◽  
Author(s):  
AS Atwal
Keyword(s):  
Body Weight ◽  
Dry Matter ◽  
Egg Laying ◽  
Lower Body ◽  
Green Leaves ◽  
Lower Body Weight ◽  
Different Temperatures ◽  
Quality Of Food ◽  
The Difference

Larvae of Plutella maculipennis (Curtis) were reared on food of different qualities at different temperatures and were exposed during their development to different photoperiods. The plants on which the larvae were reared were also exposed to different photoperiods during their development to see whether this influenced the quality of food for the insect. It was found that although caterpillars developed more quickly at 25�C than at l8�C, they weighed less at pupation at 25�C than at l8�C, but the ratio of dry matter to water was the same at both temperatures. Exposure of caterpillars to different photoperiods influenced their speed of development. There was an indication that the influence of light was different at different temperatures. The influence of quality of food was more evident. Larvae reared on white or young green leaves of cabbage developed more quickly than those reared on green but mature or senescing leaves; the slower speed of development was associated with a higher death-rate and a lower body weight combined with a higher water content of the pupae. Irrespective of temperature and the quality of the food, females developed more slowly than males and also had more dry matter and a higher liveweight in the pupal stage. Insects bred at a lower temperature produced more eggs than those at a higher temperature; the difference was thought to be due to a lower body weight in the latter. Photoperiod also influenced fecundity but the effect was not so clear. Caterpillars reared on plants grown in a long photoperiod were more fecund in the adult stage than those reared on plants grown in a short photoperiod, but the difference was not quite significant. Insects reared on white or young green leaves of cabbage laid significantly more eggs than those reared on green but mature leaves. Simarly when larvae were reared on the better quality food they produced more silk, the resulting moths lived longer, and a higher proportion of the males were fertile. The general conclusion is drawn that for normal activities of Plutella a balance of nutrients is required. For the normal activities of the insect body, like healthy development and reproduction, nutrients may be required in certain proportions. If owing to some cause (as probably, with change in season) that proportion is upset, certain abnormalities may appear in the metabolism or form of the insect, such as deformities in wings and shape of body, slower development, reduction or impediment in egg-laying capacity or diapause, etc. In the author's opinion this general conclusion may be a useful hypothesis on which to base further work. In the light of the above observations and observations on other insects, the seasonal activity of Plutella is discussed. It is stated that although apparently its behaviour and activity seem to be nicely adjusted to seasons, showing a beautiful picture of adaptation, yet the recurrent heavy reductions in numbers which this insect and many other species suffer in the field suggest that the adaptations are not as efficient as may at first sight appear.

3111t/c polymorphism of the clock gene confers a predisposition to a lifetime lower body weight in anorexia and bulimia nervosa

2007 ◽  
Vol 22 ◽  
pp. S180
Author(s):  
A. Tortorella ◽  
P. Monteleone ◽  
C. Di Filippo ◽  
A. Di Cerbo ◽  
S. Mansueto ◽  
...  
Keyword(s):  
Body Weight ◽  
Bulimia Nervosa ◽  
Clock Gene ◽  
Lower Body ◽  
Lower Body Weight

Kinect-based real-time audiovisual feedback device improves CPR quality of lower-body-weight rescuers

2018 ◽  
Vol 36 (4) ◽  
pp. 577-582 ◽  
Author(s):  
Jen-Chun Wang ◽  
Shih-Hung Tsai ◽  
Ying-Hsin Chen ◽  
Yu-Long Chen ◽  
Shi-Jye Chu ◽  
...  
Keyword(s):  
Body Weight ◽  
Real Time ◽  
Lower Body ◽  
Lower Body Weight ◽  
Cpr Quality

Pharmacotherapy for Eating Disorders

2017 ◽  
Author(s):  
Susan McElroy ◽  
Anna I. Guerdjikova ◽  
Nicole Mori ◽  
Paul E. Keck
Keyword(s):  
Eating Disorders ◽  
Anorexia Nervosa ◽  
Eating Disorder ◽  
Mental Disorders ◽  
Bulimia Nervosa ◽  
Binge Eating ◽  
Binge Eating Disorder ◽  
Night Eating Syndrome ◽  
Night Eating

This chapter addresses the pharmacotherapy of the eating disorders (EDs). Many persons with EDs receive pharmacotherapy, but pharmacotherapy research for EDs has lagged behind that for other major mental disorders. This chapter first provides a brief rationale for using medications in the treatment of EDs. It then reviews the data supporting the effectiveness of specific medications or medication classes in treating patients with anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and other potentially important EDs, such as night eating syndrome (NES). It concludes by summarizing these data and suggesting future areas for research in the pharmacotherapy of EDs.

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