Preferential TCR V usage in rat repertoire selection: Vα8 imparts both positive thymic selection by and alloreactivity to RT1f

1994 ◽  
Vol 6 (9) ◽  
pp. 1367-1373 ◽  
Author(s):  
Nora E. Torres-Nagel ◽  
Thomas Herrmann ◽  
Gerhard Glegerich ◽  
Kurt Wonigelt ◽  
Thomas Hünig
Keyword(s):  
Thymic Selection ◽  
Repertoire Selection

scholarly journals Signaling for NKT cell development

2005 ◽  
Vol 201 (6) ◽  
pp. 833-836 ◽  
Author(s):  
Christine Borowski ◽  
Albert Bendelac
Keyword(s):  
T Cell ◽  
Critical Role ◽  
Hematopoietic Cells ◽  
Adaptor Protein ◽  
Cell Development ◽  
Thymic Selection ◽  
Nkt Cell ◽  
Cell Lineages ◽  
Receptor Interactions ◽  
Slam Family

New studies demonstrate a critical role for the adaptor protein SAP (SLAM-associated protein) during NKT cell development. By connecting homotypic SLAM family receptor interactions with the FynT Src kinase, SAP may integrate a set of long-standing yet seemingly disparate observations characterizing NKT cell development. In fact, SAP-dependent signaling may underlie the development of multiple unconventional T cell lineages whose thymic selection relies on homotypic interactions between hematopoietic cells.

scholarly journals Murine thymic selection quantified using a unique method to capture deleted T cells

2013 ◽  
Vol 110 (12) ◽  
pp. 4679-4684 ◽  
Author(s):  
G. L. Stritesky ◽  
Y. Xing ◽  
J. R. Erickson ◽  
L. A. Kalekar ◽  
X. Wang ◽  
...  
Keyword(s):  
T Cells ◽  
Thymic Selection ◽  
Unique Method

IMMUNOLOGY: Proteases, Processing, and Thymic Selection

Science ◽  
1998 ◽  
Vol 280 (5362) ◽  
pp. 394-395 ◽  
Author(s):  
P. Cresswell
Keyword(s):  
Thymic Selection
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