Evaluation of Capillary Gas Chromatography for Multicomponent Drug Analysis
Keyword(s):
Abstract Capillary gas chromatography is evaluated for multicomponent drug analysis. A 0.32 mm id × 30 m fused silica column and a 0.75 mm id × 30 m borosilicate glass column (both with OV-1 bonded phase) are investigated. Retention times (relative to caffeine) are presented for 39 drug components representing a variety of chemical classes and pharmacological activities. Reproducibility data are presented for both isothermal and programmed temperature runs on selected drug mixtures. Recovery data are provided for 2 multicomponent drug mixtures prepared to approximate over-the-counter antihistaminic and antitussive preparations.
1984 ◽
Vol 315
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pp. 373-377
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1993 ◽
Vol 637
(1)
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pp. 100-103
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1984 ◽
Vol 22
(5)
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pp. 192-197
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1984 ◽
Vol 30
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pp. 1672-1674
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1983 ◽
Vol 6
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pp. 561-563
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1987 ◽
Vol 417
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pp. 295-308
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1979 ◽
Vol 3
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pp. 174-176
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2000 ◽
Vol 873
(1)
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pp. 3-11
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1995 ◽
Vol 710
(1)
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pp. 237-241
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