Voltametric Behavior of Zopiclone: Polarographic Determination in Tablets
1994 ◽
Vol 77
(3)
◽
pp. 768-773
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Keyword(s):
Abstract Electrochemical reduction of zopiclone at different pHs and concentrations was studied by polarography and cyclic voltametry. Both techniques revealed a reduction process with weak adsorption of both zopiclone and its reduction derivative. Zopiclone exhibited 2 differential pulse polarographic peaks at the dropping mercury electrode. The first peak was used to develop a differential pulse polarographic analytical procedure for determining the drug in pharmaceutical dosage forms. Reproducibility and recovery coefficients of variation were 1.6 and 2.2%, respectively. Analysis of commercial zopiclone tablets showed uniformity in zopiclone content. The method is simple and rapid because separation of excipients is unnecessary.
2018 ◽
Vol 11
(7)
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pp. 2888
2019 ◽
Vol 6
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pp. 10-19
2018 ◽
Vol 11
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pp. 3313
2016 ◽
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pp. 284
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Vol 25
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pp. 3467-3472
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1983 ◽
Vol 48
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pp. 2903-2908
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1991 ◽
Vol 56
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pp. 1434-1445
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pp. 333-341
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Vol 71
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pp. 1571-1587
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1982 ◽
Vol 134
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pp. 219-226
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