Determination of Chloramphenicol in Bovine Milk by Liquid Chromatography/Tandem Mass Spectrometry
2003 ◽
Vol 86
(4)
◽
pp. 703-706
◽
Keyword(s):
Abstract A rapid confirmatory liquid chromatographic/tandem mass spectrometic method was developed for determination of chloramphenicol in bovine milk. Chloramphenicol was extracted directly from milk by solid-phase extraction on a C18 cartridge. The extract was further cleaned up on neutral aluminium oxide. Three transition products were monitored in negative ion mode after atmospheric pressure chemical ionization. The detection capability related to the transition product of lowest abundance was 0.03 μg/kg. The mean recovery was 90% at levels of 0.1–0.2 μg/kg. The relative repeatability standard deviations were 4.3, 3.8, and 2.8% at levels of 0.1, 0.2, and 1.0 μg/kg, respectively.
1996 ◽
Vol 682
(2)
◽
pp. 249-257
◽
2012 ◽
Vol 26
(5)
◽
pp. 349-357
◽
2005 ◽
Vol 19
(16)
◽
pp. 2284-2294
◽
2011 ◽
Vol 44
(16)
◽
pp. 1329-1337
◽
1998 ◽
Vol 33
(2)
◽
pp. 138-143
◽
2004 ◽
Vol 805
(1)
◽
pp. 57-65
◽
2005 ◽
Vol 820
(1)
◽
pp. 103-110
◽
2004 ◽
Vol 378
(4)
◽
pp. 987-994
◽
2000 ◽
Vol 888
(1-2)
◽
pp. 103-111
◽