scholarly journals Acute Respiratory Infections Prevent Improvement of Vitamin A Status in Young Infants Supplemented with Vitamin A

1996 ◽  
Vol 126 (3) ◽  
pp. 628-633 ◽  
Author(s):  
M. Mujibur Rahman ◽  
D. Mahalanabis ◽  
J. O. Alvarez ◽  
M. A. Wahed ◽  
M. A. Islam ◽  
...  
2021 ◽  
Vol 8 ◽  
pp. 2333794X2110217
Author(s):  
Indah K. Murni ◽  
Endy P. Prawirohartono ◽  
Rina Triasih

Background. Vitamin C, E, D, A, zinc are considered to be essential in preventing and treating of acute respiratory infections (ARI) including COVID-19. Methods. We reviewed published studies evaluating the potential roles of these vitamin and zinc for ARIs and COVID-19 using Medline database, medRxiv, and bibliographic references. Results. Vitamins C, D, and E did not reduce incidence of common cold in general, but vitamin C reduced by half in population with physical and environment stresses. Vitamins C and E shortened duration and reduced severity of common cold. A large-dose vitamin A had no effect on recovery from pneumonia. Zinc improved clinical deterioration and pneumonia duration in under five. The effect on preventing COVID-19 morbidity and related-death was lacking. Conclusions. Although the effects of vitamins and zinc on ARIs including COVID-19 were inconclusive, taking these for a short period during pandemic may be beneficial when there is risks of deficiency.


1994 ◽  
Vol 15 (4) ◽  
pp. 1-9 ◽  
Author(s):  
George H. Beaton ◽  
Reynaldo Martorell ◽  
Kristan A. Aronson ◽  
Barry Edmonston ◽  
George McCabe. A. Catharine Ross ◽  
...  

A meta-analysis of eight mortality trials indicates that improving the vitamin A status of children aged six months to five years reduced mortality rates by about 23% in populations with at least low prevalence of clinical signs of vitamin A deficiency. The observed effect of supplementation, described in terms of relative risk (RR), was RR =0.77 (95% confidence interval 0.68–0.88; p < .001) and did not differ by sex or age. However, the number of lives saved was greater at younger ages because of higher mortality. A significant RR was shown for deaths attributed to diarrhoea and measles, but not for respiratory infection. Variability among the trials in effects was apparent, but attempts to explain it by descriptors of the population (baseline anthropometric status, prevalence of xerophthalmia, age profile, baseline mortality) were unsuccessful. Owing to the lack of data, firm conclusions could not be reached about effectiveness in children of less than six months and in settings where biochemical but not clinical evidence of vitamin A deficiency exists. Information about morbidity outcomes from about two dozen studies was reviewed. No consistent effects on frequency or prevalence of diarrhoeal and respiratory infections were found. Improvement in vitamin A status did appear to reduce severe morbidity, particularly in children with measles.


2008 ◽  
Vol 1 (1) ◽  
pp. 72-81 ◽  
Author(s):  
Kazi Md. Abul Kalam Azad

Acute respiratory infection (ARI) is a major cause of childhood mortality and morbidity in Bangladesh. The aim of this study is to identify the significant risk factors for ARI in children less than five years of age. The data in this study comes from Bangladesh Demographic and Health Survey (BDHS) 2004. In this study, a child was considered as having experienced ARI if she or he had cough in the last two weeks preceding the survey with any one of the three symptoms of short but rapid breathing, difficulty of breathing or labored inspiration. Logistic regression was used on various independent variables to find the risk factors. Results showed that child's age, sex, body weight and Vitamin A deficiency were correlated with prevalence of ARI. Additionally mother's characteristics like age, malnutrition, education level, and family's socio-economic status were found to be associated. Recommendations include more specific knowledge of ARI to adolescent mothers from the lowest wealth quintile. A community service which could include home visiting for health education, supplementation of vitamin A, and advice would be an advantage if provided for poor or teenaged pregnant women. This in turn would reduce low birth weight incidence, and subsequently reduce incidence of ARI among these children.Keywords: Acute respiratory infections (ARI); Risk factors; Infant; Child under 5 years; Bangladesh.© 2009 JSR Publications. ISSN: 2070-0237(Print); 2037-0245 (Online). All rights reserved.DOI: 10.3329/jsr.v1i1.1055


2006 ◽  
Vol 6 (5) ◽  
pp. 881-886
Author(s):  
R. Hemalatha . ◽  
Y. Kodandhapani . ◽  
N. Balakrishna .

2008 ◽  
Vol 99 (2) ◽  
pp. 102-106 ◽  
Author(s):  
Cynthia Cameron ◽  
Frédéric Dallaire ◽  
Carole Vézina ◽  
Gina Muckle ◽  
Suzanne Bruneau ◽  
...  

2014 ◽  
Vol 84 (Supplement 1) ◽  
pp. 52-59 ◽  
Author(s):  
Sherry A. Tanumihardjo ◽  
Anura V. Kurpad ◽  
Janet R. Hunt

The current use of serum retinol concentrations as a measurement of subclinical vitamin A deficiency is unsatisfactory for many reasons. The best technique available for vitamin A status assessment in humans is the measurement of total body pool size. Pool size is measured by the administration of retinol labelled with stable isotopes of carbon or hydrogen that are safe for human subjects, with subsequent measurement of the dilution of the labelled retinol within the body pool. However, the isotope techniques are time-consuming, technically challenging, and relatively expensive. There is also a need to assess different types of tracers and doses, and to establish clear guidelines for the use and interpretation of this method in different populations. Field-friendly improvements are desirable to encourage the application of this technique in developing countries where the need is greatest for monitoring the risk of vitamin A deficiency, the effectiveness of public health interventions, and the potential of hypervitaminosis due to combined supplement and fortification programs. These techniques should be applied to validate other less technical methods of assessing vitamin A deficiency. Another area of public health relevance for this technique is to understand the bioconversion of β-carotene to vitamin A, and its relation to existing vitamin A status, for future dietary diversification programs.


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