scholarly journals Combined Selenium and Vitamin E Deficiency Causes Fatal Myopathy in Guinea Pigs

2001 ◽  
Vol 131 (6) ◽  
pp. 1798-1802 ◽  
Author(s):  
Kristina E. Hill ◽  
Amy K. Motley ◽  
Xia Li ◽  
James M. May ◽  
Raymond F. Burk
1959 ◽  
Vol 197 (2) ◽  
pp. 491-493 ◽  
Author(s):  
A. D. Bender ◽  
D. D. Schottelius ◽  
B. A. Schottelius

Myoglobin concentration was determined in gastrocnemius and masseter muscles of guinea pigs maintained up to 15 days on vitamin E-deficient and vitamin E-supplemented diets. A statistically significant increase in myoglobin was noted in muscles of animals on the deficient diet for 15 days. That the increase was real and not apparent was attested by studies of total nitrogen, noncollagen nitrogen, percentage of solids and muscle wet weight, all of which were the same in control and experimental muscles. Histological sections and creatine excretion studies confirmed the impression of mild, incipient nutritional dystrophy.


1950 ◽  
Vol 48 (3) ◽  
pp. 338-345 ◽  
Author(s):  
H. M. Bruce

1. Five generations of guinea-pigs bred successfully on diet 18 supplemented with crystalline ascorbic acid but without fresh green food.2. No difference in reproductive performance was found between these animals and those of the normal breeding colony receiving unlimited supplies of fresh abbage.3. Symptoms of vitamin E deficiency appeared among some young of the fourth and fifth generations, showing that diet 18 alone contained barely enough of this factor for continuous reproduction througy many generations.4. Diet 18, supplemented by hay and fresh green food to supply vitamin C and additional vitamin E, provides all the essential factors required by the guinea-pig.


1949 ◽  
Vol 2 (4) ◽  
pp. 335-346 ◽  
Author(s):  
AXEL INGELMAN-SUNDBERG

Circulation ◽  
1996 ◽  
Vol 94 (1) ◽  
pp. 14-18 ◽  
Author(s):  
Kunihisa Miwa ◽  
Yuko Miyagi ◽  
Akihiko Igawa ◽  
Keiko Nakagawa ◽  
Hiroshi Inoue

Heliyon ◽  
2021 ◽  
pp. e07339
Author(s):  
Daniel Edem Kpewou ◽  
Faustina O. Mensah ◽  
Collins A. Appiah ◽  
Huseini Wiisibie Alidu ◽  
Vitus Sambo Badii

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