scholarly journals Oxidative DNA Damage Is Prevented by Extracts of Olive Oil, Hydroxytyrosol, and Other Olive Phenolic Compounds in Human Blood Mononuclear Cells and HL60 Cells

2008 ◽  
Vol 138 (8) ◽  
pp. 1411-1416 ◽  
Author(s):  
Roberto Fabiani ◽  
Patrizia Rosignoli ◽  
Angelo De Bartolomeo ◽  
Raffaela Fuccelli ◽  
Maurizio Servili ◽  
...  
Keyword(s):  
Dna Damage ◽  
Phenolic Compounds ◽  
Olive Oil ◽  
Human Blood ◽  
Oxidative Dna Damage ◽  
Mononuclear Cells ◽  
Hl60 Cells ◽  
Blood Mononuclear Cells

In vitro chemo-preventive activities of hydroxytyrosol: the main phenolic compound present in extra-virgin olive oil

2016 ◽  
Vol 7 (1) ◽  
pp. 301-307 ◽  
Author(s):  
Patrizia Rosignoli ◽  
Raffaela Fuccelli ◽  
Maria Vittoria Sepporta ◽  
Roberto Fabiani
Keyword(s):  
Olive Oil ◽  
Phenolic Compound ◽  
Oxidative Dna Damage ◽  
Culture Medium ◽  
Mononuclear Cells ◽  
Virgin Olive Oil ◽  
Extra Virgin Olive Oil ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells

The co-incubation in the culture medium with hydroxytyrosol [3,4-dihydroxyphenyl ethanol (3,4-DHPEA)], the main phenolic compound present in extra-virgin olive oil, and H2O2reduces the oxidative DNA damage in peripheral blood mononuclear cells (PBMC).

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