scholarly journals Alzheimer-Associated Neuronal Thread Protein-Induced Apoptosis and Impaired Mitochondrial Function in Human Central Nervous System-Derived Neuronal Cells

2001 ◽  
Vol 60 (2) ◽  
pp. 195-207 ◽  
Author(s):  
Suzanne M. de la Monte ◽  
Jack R. Wands
2009 ◽  
Vol 35 (6) ◽  
pp. 881-887 ◽  
Author(s):  
A. Izmiryan ◽  
E. Peltekian ◽  
D. Paulin ◽  
ZL Li ◽  
ZG Xue

2011 ◽  
Vol 36 (6) ◽  
pp. 1145-1145
Author(s):  
A. Izmiryan ◽  
E. Peltekian ◽  
T. Federici ◽  
D. Paulin ◽  
Z. L. Li ◽  
...  

Author(s):  
Elizabeth Hampson

Organizational and activational effects of sex steroids were first discovered in laboratory animals, but these concepts extend to hormonal actions in the human central nervous system. This chapter begins with a brief overview of how sex steroids act in the brain and how the organizational-activational hypothesis originated in the field of endocrinology. It then reviews common methods used to study these effects in humans. Interestingly, certain cognitive functions appear to be subject to modification by sex steroids, and these endocrine influences may help explain the sex differences often seen in these functions. The chapter considers spatial cognition as a representative example because the spatial family of functions has received the most study by researchers interested in the biological roots of sex differences in cognition. The chapter reviews evidence that supports an influence of both androgens and estrogens on spatial functions, and concludes with a glimpse of where the field is headed.


1986 ◽  
Vol 11 (3) ◽  
pp. 205-214 ◽  
Author(s):  
Magnhild Sandberg-Wollheim ◽  
Burton Zweiman ◽  
Arnold I. Levinson ◽  
Robert P. Lisak

Author(s):  
Mehrak Mahmoudi ◽  
Piroz Zamankhan ◽  
William Polashenski

The nervous system remains one of the least understood biological structures due in large part to the enormous complexity of this organ. A theoretical model for the transfer of nerve impulses would be valuable for the analysis of various phenomena in the nervous system, which are difficult to study by experiments. The central nervous system is composed of more than 100 billion neurons, through which information is transmitted via nerve impulses. Nerve impulses are not immediately apparent since each impulse may be blocked during transmission, changed from a single impulse into repetitive impulse, or integrated with impulses from other neurons to form highly intricate patterns. In the human central nervous system, a neuron secretes a chemical substance called a neurotransmitter at the synapse, and this transmitter in turn acts on another neuron to cause excitation, inhibition, or some other modification of its sensitivity.


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