scholarly journals EBV-associated mucocutaneous ulcer, a rare cause of a frequent problem

2020 ◽  
Vol 2020 (4) ◽  
Author(s):  
Gabriel Fridolin Hess ◽  
Thomas Menter ◽  
Daniel Boll ◽  
Jürg Steiger ◽  
Marco von Strauss und Torney
Keyword(s):  
Renal Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Rubber Band ◽  
Lymphoproliferative Disease ◽  
Rectal Ulcer ◽  
Barr Virus ◽  
Immunosuppressed Patients ◽  
Hemorrhoidal Prolapse ◽  
Frequent Problem

Abstract This report presents a 74-year-old renal transplant patient suffering of polymorphic-post-transplant-associated lymphoproliferative disease (P-PTLD) within an Eppstein-Barr Virus (EBV) associated mucocutaneous rectal ulcer (MCU). He was initially treated by stapled hemorrhoidopexy for a symptomatic grade III hemorrhoidal prolapse refractory to conservative treatment and rubber band ligations. This leads to severe urge, frequency and stool fragmentation. The symptoms were investigated with a number of interventions until a proctoscopy with biopsies finally revealed the diagnosis. The patient had triple therapy of tacrolimus, mycophenolate mofetil and prednisone initially after transplant several years ago with recent reduction to mycophenolate. The MCU was successfully treated with Retuximab and there was no sign of relaps after 6 months. As EBV-associated PTLD is a well known complication after renal transplant, rectum-MCU seems a rare and only recently described subform of this disease that should be excluded in case of ulcerating lesions in immunosuppressed patients.

scholarly journals Life-threatening Epstein–Barr virus (EBV)-related hepatitis in a renal transplant patient

2020 ◽  
Vol 20 (Suppl 2) ◽  
pp. s38-s38
Author(s):  
Faisal Rehman ◽  
Yahya Makkeyah ◽  
Abdul-Aema Buraq ◽  
Georgina Aldous ◽  
Sohail Ahmad
Keyword(s):  
Renal Transplant ◽  
Epstein Barr Virus ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Barr Virus ◽  
Life Threatening ◽  
Epstein Barr

Rigorous Vibrio vulnificus Soft Tissue Infection of the Lower Leg in a Renal Transplant Patient Managed by Vacuum Therapy and Autologous Growth Factors

2009 ◽  
Vol 13 (4) ◽  
pp. 209-214 ◽  
Author(s):  
Elias Thodis ◽  
Pelagia Kriki ◽  
Despoina Kakagia ◽  
Ploumis Passadakis ◽  
Marios Theodoridis ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Renal Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Vibrio Vulnificus ◽  
Healing Process ◽  
Opportunistic Pathogen ◽  
Vacuum Therapy ◽  
Autologous Platelet Concentrate ◽  
Immunosuppressed Patients

Background: Vibrio vulnificus is a gram-negative marine bacterium that grows well in coastal waters. It is an opportunistic pathogen that can cause serious life-threatening infections in patients with certain health conditions. Vibrio-induced wound infections in immunosuppressed patients are difficult to treat because the healing process may be significantly delayed. Reconstructive surgery may not be successful in early treatment as skin grafts are likely to fail, and there may be increased morbidity of donor sites of grafts or flaps. Objective: Herein a case of septicemia and wound necrosis owing to V. vulnificus wound infection in a renal transplant patient is reported. Method: To conservatively yet adequately débride the wound bed, stimulate angiogenesis, and accelerate granulation, vacuum-assisted closure was employed. Granulation was further enhanced by autologous platelet concentrate spray, which has also been reported to increase the epithelialization rate. Result: Complete epithelialization of the wound was achieved 4 weeks after completion of treatment. Conclusion: Noninvasive advanced modalities may be employed to successfully treat infectious soft tissue deficits in immunocompromised patients.

Epstein-Barr Virus-Associated High-Grade Anaplastic Plasmacytoma in a Renal Transplant Patient

2000 ◽  
Vol 36 (3-4) ◽  
pp. 411-415 ◽  
Author(s):  
H. A. Papadaki ◽  
K. Stefanaki ◽  
P. Kanavaros ◽  
P. Katonis ◽  
H. Papastathi ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Epstein Barr Virus ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
High Grade ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Treatment of cardiac nocardiosis in a post-renal transplant patient of systemic nocardiosis

2019 ◽  
Vol 11 (2) ◽  
pp. 161-163 ◽  
Author(s):  
Muddassar Mahboob ◽  
Sana Hassan ◽  
Ashraf Ali Attia ◽  
Ebadur Rahman ◽  
Muhammad Shoaib Khan ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Antimicrobial Therapy ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Interesting Case ◽  
Organ System ◽  
The Body ◽  
Pulmonary System ◽  
Immunosuppressed Patients

In general, nocardia infects immunosuppressed patients, however, sometimes it can also infect immunocompetent individuals. Nocardia infection can disseminate to any organ system of the body but the pulmonary system is the most commonly involved system. In some rare cases, the heart can also be involved and the resulting cardiac mycetoma can be treated successfully with antimicrobials without the need of surgery, unlike fungal cardiac mycetomas wherein surgery may be required in addition to antimicrobial therapy. We present an interesting case of post-renal transplant cardiac nocardiosis, which was treated successfully with a course of antibiotics.

scholarly journals AspergillusPericarditis with Tamponade in a Renal Transplant Patient

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Sylvia Biso ◽  
Rapeepat Lekkham ◽  
Antoinette Climaco
Keyword(s):  
Renal Transplant ◽  
Cardiac Tamponade ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Clinical Manifestations ◽  
Pericardial Fluid ◽  
Immunosuppressed Patients ◽  
Life Threatening ◽  
Disease Entities ◽  
High Degree

Aspergilluspericarditis is a rare and life-threatening infection in immunosuppressed patients. It has nonspecific clinical manifestations that often mimic other disease entities especially in patients who have extensive comorbidities. Diagnosis is oftentimes delayed and rarely done antemortem. A high degree of suspicion in immunocompromised patients is necessary for evaluation and timely diagnosis. This is a case ofAspergilluspericarditis with cardiac tamponade in a renal transplant patient with liver cirrhosis. Two months after transplant, he developed decompensation of his cirrhosis from hepatitis C, acute cellular rejection, andKluyverabacteremia, followed by vancomycin-resistantEnterococcus faecium(VRE) bacteremia. Four months after transplant, the patient presented with lethargy and fluid overload. He subsequently developed shock and ventilator-dependent respiratory failure. An echocardiogram showed pericardial effusion with cardiac tamponade. He had emergent pericardiocentesis that showed purulent drainage. He was started on broad-spectrum antibiotics. Amphotericin B was initiated when the pericardial fluid grew mold that was later identified asAspergillus fumigatus. The patient quickly decompensated and expired.

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