scholarly journals The effect of autologous adipose derived mesenchymal stem cell therapy on juvenile osteochondritis dissecans of the patella: a case study

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Alessandro Russo ◽  
Vito Coco ◽  
Stefano Zaffagnini
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Osteochondritis Dissecans ◽  
Prospective Analysis ◽  
Resonance Imaging ◽  
Mesenchymal Stem Cell Therapy ◽  
Conventional Management ◽  
Juvenile Osteochondritis Dissecans ◽  
Pain Improvement

Abstract A prospective analysis of the effect of autologous adipose derived mesenchymal stem cell (AD-MSCs) therapy in the treatment of a juvenile osteochondritis dissecans (JOCD) of the patella. After failed conventional management of JOCD, a 13-year-old patient undergoes intra-articular MSC therapy. Repeated magnetic resonance imaging analyses showed regeneration of cartilage. In this report, the use of AD-MSCs, after unsuccessful conventional JOCD management, resulted in structural, functional and pain improvement. These results highlight the possibility to avoid surgery treatment in JOCD patella treatment.

Mesenchymal Stem Cell Therapy for Oral Inflammatory Diseases: Research Progress and Future Perspectives

2020 ◽  
Vol 15 ◽  
Author(s):  
Wang Gong ◽  
Fei Wang ◽  
Yuqing He ◽  
Blake Heath ◽  
Xin Zeng ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Immune Regulation ◽  
Tissue Damage ◽  
Inflammatory Diseases ◽  
Allergic Diseases ◽  
Research Progress ◽  
Epithelial Tissue ◽  
Oral Diseases ◽  
Mesenchymal Stem Cell Therapy

: Mesenchymal stem cell (MSC) therapy for clinical diseases associated with inflammation and tissue damage has become a progressive treatment strategy. MSCs have unique biological functions, such as homing, immune regulation, and differentiation capabilities, which provide the prerequisites for treatment of clinical diseases. Oral diseases are often associated with abnormal immune regulation and epithelial tissue damage. In this review, we summarize previous studies that use MSC therapy to treat various oral inflammatory diseases, including oral ulceration, allergic diseases, chemo/radiotherapy-induced oral mucositis, periodontitis, osteonecrosis of the jaw, Sjögren's syndrome (SS), among other similar diseases. We highlight MSC treatment as a promising approach in the management of oral inflammatory diseases, and discuss the obstacles that remain and must be overcome for MSC treatment to thrive in the future.

Steroids reduce the efficacy of mesenchymal stem cell therapy for liver cirrhosis

Cytotherapy ◽  
2015 ◽  
Vol 17 (6) ◽  
pp. S48-S50 ◽  
Author(s):  
Xiaodong Chen ◽  
Yurun Gan ◽  
Ying Wang ◽  
Yufang Shi
Keyword(s):  
Liver Cirrhosis ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Mesenchymal Stem Cell Therapy
Sign in / Sign up

Export Citation Format

Share Document