The CardioMEMS Heart Failure Monitoring System

Author(s):  
Brent C. Lampert ◽  
William T. Abraham

The initial cause of worsening heart failure is increased intracardiac and pulmonary pressures. Traditional non-invasive heart failure monitoring strategies that follow surrogates of increased pressures have not reduced heart failure hospitalizations. Pulmonary artery pressure measurements using the implantable CardioMEMS system allow daily remote monitoring and earlier identification of heart failure decompensations. In the CHAMPION trial, remote monitoring with the CardioMEMS Heart Failure system significantly reduced hospitalizations for heart failure, even in patients with numerous comorbidities. For patients with refractory advanced heart failure, mechanical circulatory support can markedly improve the length and quality of life but can also have multiple complications. Implantable hemodynamic monitoring with CardioMEMS may provide clinicians with better information to guide the timing of left ventricular assist device implantation and to improve post-implant care.

2015 ◽  
Vol 1 (1) ◽  
pp. 25 ◽  
Author(s):  
Edo Y Birati ◽  
Mariell Jessup ◽  
◽  

Mechanical circulatory support has emerged as an important therapy for advanced heart failure, with more than 18,000 continuous flow devices implanted worldwide to date. These devices significantly improve survival and quality of life and should be considered in every patient with end-stage heart failure with reduced ejection fraction who has no other life-limiting diseases. All candidates for device implantation should undergo a thorough evaluation in order to identify those who could benefit from device implantation. Long-term management of ventricular assist device patients is challenging and requires knowledge of the characteristic complications with their unique clinical presentations.


2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Selim Bozkurt ◽  
Koray K. Safak

Dilated cardiomyopathy is the most common type of the heart failure which can be characterized by impaired ventricular contractility. Mechanical circulatory support devices were introduced into practice for the heart failure patients to bridge the time between the decision to transplant and the actual transplantation which is not sufficient due to the state of donor organ supply. In this study, the hemodynamic response of a cardiovascular system that includes a dilated cardiomyopathic heart under support of a newly developed continuous flow left ventricular assist device—Heart Turcica Axial—was evaluated employing computer simulations. For the evaluation, a numerical model which describes the pressure-flow rate relations of Heart Turcica Axial, a cardiovascular system model describing the healthy and pathological hemodynamics, and a baroreflex model regulating the heart rate were used. Heart Turcica Axial was operated between 8000 rpm and 11000 rpm speeds with 1000 rpm increments for assessing the pump performance and response of the cardiovascular system. The results also give an insight about the range of the possible operating speeds of Heart Turcica Axial in a clinical application. Based on the findings, operating speed of Heart Turcica Axial should be between 10000 rpm and 11000 rpm.


Author(s):  
Alain Combes

Despite major advances in pharmacological therapies for heart failure with left ventricular pump dysfunction, the number of hospitalizations for decompensated heart failure is increasing, with most patients ultimately dying of disease complications. Heart transplantation remains the only treatment providing substantial individual benefit for patients with advanced disease. However, fewer than 3000 organ donors are available worldwide per year, limiting its overall impact. Therefore, alternative approaches, such as mechanical circulatory support have been the subject of intense research over recent decades. The development of mechanical circulatory devices parallels that of cardiac surgery and cardiac transplantation. Current practice and the development of economically affordable short-term devices have resulted in updated indications for mechanical circulatory assistance for both short- and long-term support.


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